create database and tables

import sqlite3
from flask import Flask, render_template
app = Flask(__name__)

conn = sqlite3.connect('example.db')
c = conn.cursor()
c.execute('''CREATE TABLE emails
             (name text, email text)''')

c.execute("INSERT INTO emails VALUES ('melinda gates', 'bill@microsoft.com')")
conn.commit()

@app.route("/")
def hello(name="HAPPPPPPY"):
    return render_template('hello.html',name=name)

@app.route("/MO")
def MO():
    return "string"

if __name__ == "__main__":
    app.run()

https://docs.python.org/2/library/sqlite3.html

virtualenv venv
source venv/bin/activate
pip install flask
python app.py