gistfile1.html

<a class="btn">My Button</a>

test.js

$('.btn').popover({
  container: 'body',
  content: 'my content',
  trigger: 'manual'
});

// Since we're controlling the popover lifecycle, we need to show it.
$('.btn').popover('show');

// Now its time to kill it, later in our code
$('.btn').popover('destroy');

// If we call show again, the popover content is broken:
$('.btn').popover('show');

// So we have to call removeData to clean up after bootstrap
$('.btn').removeData('bs.popover');