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#Predictive model from GENDEP data | |
#Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables. | |
#Raquel Iniesta raquel.iniesta@kcl.ac.uk | |
#Use the model to estimate the probability of remission (yes or not) for a patient of depression after 12 weeks of treatment with Escitalopram. | |
#List of baseline predictors that are necessary for the prediction: | |
#CLINICAL variables: | |
#appetite defined as in R. Uher et al. Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms Psychol. Med., 42 (2012), pp. 967–980 | |
#BDI_changes_sleep is the score for BDI item number |
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#Predictive model from GENDEP data published in J Psychiatr Res. 2016 Jul;78:94-102. doi: #10.1016/j.jpsychires.2016.03.016. | |
#Combining clinical variables to optimize prediction of antidepressant treatment outcomes. | |
#Raquel Iniesta raquel.iniesta@kcl.ac.uk | |
#Use the model to estimate the percentage of depressive symptoms improvement for a patient of depression. | |
#Outcome predicted is the percentage of improvement measured with MADRS scale after 12 weeks of treatment with Escitalopram. | |
#list of 14 baseline predictors that are necessary to predict the outcome. | |
# MADRS_10 is the score for MADRS item number 10 |