gistfile1.txt

import sys
from django.conf import settings

settings.configure(
    DEBUG=True,
    SECRET_KEY='thisisthesecretkey',
    ROOT_URLCONF=__name__,
    MIDDLEWARE_CLASSES=(
        'django.middleware.common.CommonMiddleware',
        'django.middleware.csrf.CsrfViewMiddleware',
        'django.middleware.clickjacking.XFrameOptionsMiddleware',
    ),
)

from django.conf.urls import url
from django.http import HttpResponse

def index(request):
    return HttpResponse('Aloha!')

urlpatterns = (url(r'^$', index),)
if __name__ == "__main__":
    from django.core.management import execute_from_command_line
    execute_from_command_line(sys.argv)

Nice one, back to basics.
You could also leave out all the MIDDLEWARE_CLASSES and SECRET_KEY to go barebones.