Example SPA

Project Structure
- index.js //Your NodeJs code
- /public // What in here is your tradition Angular App (like the one on Angular Tutorial)
    - /css
    - /js
      - app.js // Your Angular code
    - index.html

================= Server Side =============================
//Node index.js
var express = require('express');
var app     = express();

app.use(express.static(__dirname + '/public');
app.listen(1337);

================= Client Side ==============================
//index.html
....
<script src="/js/app.js"></script>

//Angular app.js
var app = angular.module('app', []);
var services = angular.module('services', []);

================= Bonuses ===================================
Yeah, having all javascript on one file (app.js) sucks
Just write multiple module on different files, and use some build tool (GulpJs, GruntJs, etc) to concat them
Your project structure then
/public
  - /build //Expose this directory over express.static
    - /js
      - app.js //Yep only one file after build, this is important because in your html you only have a single script tag for app.js
  - /src
    - /js
      - /controllers
      - /services
      - app.module.js
      - services.module.js