- set up the 6 keys above the arrow keys as global hotkeys for 6 equal segments of the screen (and then the same with the 9 numpad keys)
- An alternative to divvy is moom which can memorize layouts
- play around a bunch with the color settings
- Turn off any Picture Mode effects (ie - 'sharpening' or 'motion' TV processing in the TV setup)
- Enable game-mode if possible. You may have to plug in a console (e.g. PS3, etc.) to do it, but do it on that HDMI port and then plug your computer in.