Remove plugin completely from admin (hide it), to prevent deactivation.

hide plugin

// hide plugins in admin
add_filter( 'all_plugins', 'hide_plugins');
function hide_plugins($plugins)
{
  // Hide hello dolly plugin
	if(is_plugin_active('hello.php')) {
		unset( $plugins['hello.php'] );
	}

	// Hide disqus plugin
	if(is_plugin_active('disqus-comment-system/disqus.php')) {
		unset( $plugins['disqus-comment-system/disqus.php'] );
	}

	return $plugins;
}