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import arcpy, os

outDir= r'C:\MyImageFolder'
mxdPath = r'C:\MyMap.mxd'

mxd = arcpy.mapping.MapDocument(mxdPath)
df = mxd.activeDataFrame

counter = 0
myTime = df.time.startTime

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#Import python libraries
import arcpy, os
from PyPDF2 import PdfFileWriter, PdfFileReader

#Creates two empty pdf documents
print("Creating pdf document")
myPDFPath = r'C:\MyNewFile.pdf'
myPDFPathArcGIS = os.path.join(os.path.dirname(myPDFPath),'My_Temporary_File.pdf')
myPDFArcGIS = arcpy.mapping.PDFDocumentCreate(myPDFPathArcGIS)

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def sequentialByX(lyr, orderFld):
  #'lyr' is the name of your layer in ArcMap
  #'orderFld' is the name of the field that you want to populate with sequential numbers
  
  #First let's get a list of x coordinates and the corresponding objectid
  coordLst = []
  idFld = arcpy.Describe(lyr).OIDFieldName
  rows = arcpy.da.SearchCursor(lyr,["SHAPE@X", idFld])
  for row in rows:
    coordLst.append([row[0], row[1]])

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def assignSequentialNumbers(lyr, fldID, fldSort):
    #lyr = a point layer in your mxd, such as Cities from the example above
    #fldID = the field in lyr to which you would like to assign numbers, such as "Rank" in example above
    #fldSort = the field in lyr by which you would like to sort, such as "Name" in the example above
    with arcpy.da.SearchCursor(lyr, fldSort) as rows:
        myLst = []
        for row in rows:
            myLst.append(row[0])
    myLst.sort()
    myDict = {}