Glassfish 4.1において、JerseyリソースにCDIでインジェクトできない。というハマリの記録 ref: http://qiita.com/sengoku/items/237e7587be3674f82334

ApplicationConfig.java

@javax.ws.rs.ApplicationPath("/")
public class ApplicationConfig extends Application {

    @Override
    public Set<Class<?>> getClasses() {
        Set<Class<?>> resources = new java.util.HashSet<>();
        addRestResourceClasses(resources);
        return resources;
    }

    /**
     * Do not modify addRestResourceClasses() method.
     * It is automatically populated with
     * all resources defined in the project.
     * If required, comment out calling this method in getClasses().
     */
    private void addRestResourceClasses(Set<Class<?>> resources) {
        resources.add(com.example.GenericResource.class);
    }

}

file3.txt

Warning:   The following warnings have been detected: WARNING: Unknown HK2 failure detected:
MultiException stack 1 of 1
org.glassfish.hk2.api.UnsatisfiedDependencyException: There was no object available for injection at SystemInjecteeImpl(requiredType=UserSession,parent=GenericResource,qualifiers={},position=-1,optional=false,self=false,unqualified=null,1850411141)
    at org.jvnet.hk2.internal.ThreeThirtyResolver.resolve(ThreeThirtyResolver.java:74)
    at org.jvnet.hk2.internal.Utilities.justInject(Utilities.java:947)
    at org.jvnet.hk2.internal.ServiceLocatorImpl.inject(ServiceLocatorImpl.java:902)
    at org.glassfish.jersey.gf.cdi.internal.CdiComponentProvider$CdiFactory$2.getInstance(CdiComponentProvider.java:245)
    at org.glassfish.jersey.gf.cdi.internal.CdiComponentProvider$CdiFactory.provide(CdiComponentProvider.java:189)
    at org.jvnet.hk2.internal.FactoryCreator.create(FactoryCreator.java:124)
    at org.jvnet.hk2.internal.SystemDescriptor.create(SystemDescriptor.java:461)
    at org.jvnet.hk2.internal.PerLookupContext.findOrCreate(PerLookupContext.java:69)
    at org.jvnet.hk2.internal.Utilities.createService(Utilities.java:2258)
    at org.jvnet.hk2.internal.ServiceLocatorImpl.internalGetService(ServiceLocatorImpl.java:690)
    at org.jvnet.hk2.internal.ServiceLocatorImpl.getService(ServiceLocatorImpl.java:655)
    at org.glassfish.jersey.internal.inject.Injections.getOrCreate(Injections.java:172)
    at org.glassfish.jersey.server.model.MethodHandler$ClassBasedMethodHandler.getInstance(MethodHandler.java:185)
    at org.glassfish.jersey.server.internal.routing.PushMethodHandlerRouter.apply(PushMethodHandlerRouter.java:74)
    at org.glassfish.jersey.server.internal.routing.RoutingStage._apply(RoutingStage.java:112)
    at org.glassfish.jersey.server.internal.routing.RoutingStage._apply(RoutingStage.java:115)
    at org.glassfish.jersey.server.internal.routing.RoutingStage._apply(RoutingStage.java:115)
    at org.glassfish.jersey.server.internal.routing.RoutingStage._apply(RoutingStage.java:115)
    at org.glassfish.jersey.server.internal.routing.RoutingStage.apply(RoutingStage.java:94)
    at org.glassfish.jersey.server.internal.routing.RoutingStage.apply(RoutingStage.java:63)
    at org.glassfish.jersey.process.internal.Stages.process(Stages.java:197)
    at org.glassfish.jersey.server.ServerRuntime$1.run(ServerRuntime.java:263)
    at org.glassfish.jersey.internal.Errors$1.call(Errors.java:271)
    at org.glassfish.jersey.internal.Errors$1.call(Errors.java:267)
    at org.glassfish.jersey.internal.Errors.process(Errors.java:315)
    at org.glassfish.jersey.internal.Errors.process(Errors.java:297)
    at org.glassfish.jersey.internal.Errors.process(Errors.java:267)
    at org.glassfish.jersey.process.internal.RequestScope.runInScope(RequestScope.java:297)
    at org.glassfish.jersey.server.ServerRuntime.process(ServerRuntime.java:254)
    at org.glassfish.jersey.server.ApplicationHandler.handle(ApplicationHandler.java:1028)
    at org.glassfish.jersey.servlet.WebComponent.service(WebComponent.java:372)
    at org.glassfish.jersey.servlet.ServletContainer.service(ServletContainer.java:381)
    at org.glassfish.jersey.servlet.ServletContainer.service(ServletContainer.java:344)
    at org.glassfish.jersey.servlet.ServletContainer.service(ServletContainer.java:221)
    at org.apache.catalina.core.StandardWrapper.service(StandardWrapper.java:1682)
    at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:318)
    at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:160)
    at org.apache.catalina.core.StandardPipeline.doInvoke(StandardPipeline.java:734)
    at org.apache.catalina.core.StandardPipeline.invoke(StandardPipeline.java:673)
    at com.sun.enterprise.web.WebPipeline.invoke(WebPipeline.java:99)
    at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:174)
    at org.apache.catalina.connector.CoyoteAdapter.doService(CoyoteAdapter.java:415)
    at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:282)
    at com.sun.enterprise.v3.services.impl.ContainerMapper$HttpHandlerCallable.call(ContainerMapper.java:459)
    at com.sun.enterprise.v3.services.impl.ContainerMapper.service(ContainerMapper.java:167)
    at org.glassfish.grizzly.http.server.HttpHandler.runService(HttpHandler.java:201)
    at org.glassfish.grizzly.http.server.HttpHandler.doHandle(HttpHandler.java:175)
    at org.glassfish.grizzly.http.server.HttpServerFilter.handleRead(HttpServerFilter.java:235)
    at org.glassfish.grizzly.filterchain.ExecutorResolver$9.execute(ExecutorResolver.java:119)
    at org.glassfish.grizzly.filterchain.DefaultFilterChain.executeFilter(DefaultFilterChain.java:284)
    at org.glassfish.grizzly.filterchain.DefaultFilterChain.executeChainPart(DefaultFilterChain.java:201)
    at org.glassfish.grizzly.filterchain.DefaultFilterChain.execute(DefaultFilterChain.java:133)
    at org.glassfish.grizzly.filterchain.DefaultFilterChain.process(DefaultFilterChain.java:112)
    at org.glassfish.grizzly.ProcessorExecutor.execute(ProcessorExecutor.java:77)
    at org.glassfish.grizzly.nio.transport.TCPNIOTransport.fireIOEvent(TCPNIOTransport.java:561)
    at org.glassfish.grizzly.strategies.AbstractIOStrategy.fireIOEvent(AbstractIOStrategy.java:112)
    at org.glassfish.grizzly.strategies.WorkerThreadIOStrategy.run0(WorkerThreadIOStrategy.java:117)
    at org.glassfish.grizzly.strategies.WorkerThreadIOStrategy.access$100(WorkerThreadIOStrategy.java:56)
    at org.glassfish.grizzly.strategies.WorkerThreadIOStrategy$WorkerThreadRunnable.run(WorkerThreadIOStrategy.java:137)
    at org.glassfish.grizzly.threadpool.AbstractThreadPool$Worker.doWork(AbstractThreadPool.java:565)
    at org.glassfish.grizzly.threadpool.AbstractThreadPool$Worker.run(AbstractThreadPool.java:545)
    at java.lang.Thread.run(Thread.java:745)

GenericResource.java

import javax.inject.Inject;
import javax.ws.rs.Produces;
import javax.ws.rs.GET;
import javax.ws.rs.Path;

@Path("/")
public class GenericResource {

    @Inject
    private UserSession userSession;

    @GET
    @Produces("text/plain")
    public String getText() {
        return "Hello " + userSession.getUserName();
    }
}

UserSession.java

import java.io.Serializable;
import javax.annotation.PostConstruct;
import javax.enterprise.context.SessionScoped;

@SessionScoped
public class UserSession implements Serializable {
    private static final long serialVersionUID = 1L;
    private String userName;

    @PostConstruct
    public void init() {
        this.setUserName(String.valueOf(Math.random()));
    }

    public String getUserName() {
        return userName;
    }

    public void setUserName(String userName) {
        this.userName = userName;
    }
}

This could be fixed by turning the GenericResource into a contextual bean with a clearly defined scope.
I presume @javax.enterprise.context.RequestScoped was intended here.