The skeleton of the game is there. X and O take turns and the gameboard updates with each round.

A (very) Simple Game of Tic Tac Toe

theBoard = {'top-L': ' ', 'top-M': ' ', 'top-R': ' ',
            'mid-L': ' ', 'mid-M': ' ', 'mid-R': ' ',
            'low-L': ' ', 'low-M': ' ', 'low-R': ' '}

def printBoard(board):
    print(board['top-L'] + '|' + board['top-M'] + '|'+ board['top-R'])
    print('-+-+-')
    print(board['mid-L'] + '|' + board['mid-M'] + '|'+ board['mid-R'])
    print('-+-+-')
    print(board['low-L'] + '|' + board['low-M'] + '|'+ board['low-R'])
turn = 'X'
for i in range(9):
    printBoard(theBoard)
    print ('Turn for ' + turn + '.  Move on which space?')
    move = input()
    theBoard[move] = turn
    if turn == 'X':
        turn = 'O'
    else:
        turn = 'X'
printBoard(theBoard)