-
-
Save smsaladi/6adb30efbe70f9fed0306b226e8ad0d8 to your computer and use it in GitHub Desktop.
Sample html document with nested tables
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| <!DOCTYPE html SYSTEM "about:legacy-compat"> | |
| <!-- saved from url=(0086)https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score --> | |
| <html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en"><script type="text/javascript">window["_gaUserPrefs"] = { ioo : function() { return true; } }</script><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><style type="text/css">.tippy-iOS{cursor:pointer!important}.tippy-notransition{transition:none!important}.tippy-popper{-webkit-perspective:700px;perspective:700px;z-index:9999;outline:0;transition-timing-function:cubic-bezier(.165,.84,.44,1);pointer-events:none;line-height:1.4}.tippy-popper[x-placement^=top] .tippy-backdrop{border-radius:40% 40% 0 0}.tippy-popper[x-placement^=top] .tippy-roundarrow{bottom:-8px;-webkit-transform-origin:50% 0;transform-origin:50% 0}.tippy-popper[x-placement^=top] .tippy-roundarrow svg{position:absolute;left:0;-webkit-transform:rotate(180deg);transform:rotate(180deg)}.tippy-popper[x-placement^=top] .tippy-arrow{border-top:8px solid #333;border-right:8px solid transparent;border-left:8px solid transparent;bottom:-7px;margin:0 6px;-webkit-transform-origin:50% 0;transform-origin:50% 0}.tippy-popper[x-placement^=top] .tippy-backdrop{-webkit-transform-origin:0 25%;transform-origin:0 25%}.tippy-popper[x-placement^=top] .tippy-backdrop[data-state=visible]{-webkit-transform:scale(1) translate(-50%,-55%);transform:scale(1) translate(-50%,-55%)}.tippy-popper[x-placement^=top] .tippy-backdrop[data-state=hidden]{-webkit-transform:scale(.2) translate(-50%,-45%);transform:scale(.2) translate(-50%,-45%);opacity:0}.tippy-popper[x-placement^=top] [data-animation=shift-toward][data-state=visible]{-webkit-transform:translateY(-10px);transform:translateY(-10px)}.tippy-popper[x-placement^=top] [data-animation=shift-toward][data-state=hidden]{opacity:0;-webkit-transform:translateY(-20px);transform:translateY(-20px)}.tippy-popper[x-placement^=top] [data-animation=perspective]{-webkit-transform-origin:bottom;transform-origin:bottom}.tippy-popper[x-placement^=top] [data-animation=perspective][data-state=visible]{-webkit-transform:translateY(-10px) rotateX(0);transform:translateY(-10px) rotateX(0)}.tippy-popper[x-placement^=top] [data-animation=perspective][data-state=hidden]{opacity:0;-webkit-transform:translateY(0) rotateX(60deg);transform:translateY(0) rotateX(60deg)}.tippy-popper[x-placement^=top] [data-animation=fade][data-state=visible]{-webkit-transform:translateY(-10px);transform:translateY(-10px)}.tippy-popper[x-placement^=top] [data-animation=fade][data-state=hidden]{opacity:0;-webkit-transform:translateY(-10px);transform:translateY(-10px)}.tippy-popper[x-placement^=top] [data-animation=shift-away][data-state=visible]{-webkit-transform:translateY(-10px);transform:translateY(-10px)}.tippy-popper[x-placement^=top] [data-animation=shift-away][data-state=hidden]{opacity:0;-webkit-transform:translateY(0);transform:translateY(0)}.tippy-popper[x-placement^=top] [data-animation=scale][data-state=visible]{-webkit-transform:translateY(-10px) scale(1);transform:translateY(-10px) scale(1)}.tippy-popper[x-placement^=top] [data-animation=scale][data-state=hidden]{opacity:0;-webkit-transform:translateY(0) scale(.5);transform:translateY(0) scale(.5)}.tippy-popper[x-placement^=bottom] .tippy-backdrop{border-radius:0 0 30% 30%}.tippy-popper[x-placement^=bottom] .tippy-roundarrow{top:-8px;-webkit-transform-origin:50% 100%;transform-origin:50% 100%}.tippy-popper[x-placement^=bottom] .tippy-roundarrow svg{position:absolute;left:0;-webkit-transform:rotate(0);transform:rotate(0)}.tippy-popper[x-placement^=bottom] .tippy-arrow{border-bottom:8px solid #333;border-right:8px solid transparent;border-left:8px solid transparent;top:-7px;margin:0 6px;-webkit-transform-origin:50% 100%;transform-origin:50% 100%}.tippy-popper[x-placement^=bottom] .tippy-backdrop{-webkit-transform-origin:0 -50%;transform-origin:0 -50%}.tippy-popper[x-placement^=bottom] .tippy-backdrop[data-state=visible]{-webkit-transform:scale(1) translate(-50%,-45%);transform:scale(1) translate(-50%,-45%)}.tippy-popper[x-placement^=bottom] .tippy-backdrop[data-state=hidden]{-webkit-transform:scale(.2) translate(-50%);transform:scale(.2) translate(-50%);opacity:0}.tippy-popper[x-placement^=bottom] [data-animation=shift-toward][data-state=visible]{-webkit-transform:translateY(10px);transform:translateY(10px)}.tippy-popper[x-placement^=bottom] [data-animation=shift-toward][data-state=hidden]{opacity:0;-webkit-transform:translateY(20px);transform:translateY(20px)}.tippy-popper[x-placement^=bottom] [data-animation=perspective]{-webkit-transform-origin:top;transform-origin:top}.tippy-popper[x-placement^=bottom] [data-animation=perspective][data-state=visible]{-webkit-transform:translateY(10px) rotateX(0);transform:translateY(10px) rotateX(0)}.tippy-popper[x-placement^=bottom] [data-animation=perspective][data-state=hidden]{opacity:0;-webkit-transform:translateY(0) rotateX(-60deg);transform:translateY(0) rotateX(-60deg)}.tippy-popper[x-placement^=bottom] [data-animation=fade][data-state=visible]{-webkit-transform:translateY(10px);transform:translateY(10px)}.tippy-popper[x-placement^=bottom] [data-animation=fade][data-state=hidden]{opacity:0;-webkit-transform:translateY(10px);transform:translateY(10px)}.tippy-popper[x-placement^=bottom] [data-animation=shift-away][data-state=visible]{-webkit-transform:translateY(10px);transform:translateY(10px)}.tippy-popper[x-placement^=bottom] [data-animation=shift-away][data-state=hidden]{opacity:0;-webkit-transform:translateY(0);transform:translateY(0)}.tippy-popper[x-placement^=bottom] [data-animation=scale][data-state=visible]{-webkit-transform:translateY(10px) scale(1);transform:translateY(10px) scale(1)}.tippy-popper[x-placement^=bottom] [data-animation=scale][data-state=hidden]{opacity:0;-webkit-transform:translateY(0) scale(.5);transform:translateY(0) scale(.5)}.tippy-popper[x-placement^=left] .tippy-backdrop{border-radius:50% 0 0 50%}.tippy-popper[x-placement^=left] .tippy-roundarrow{right:-16px;-webkit-transform-origin:33.33333333% 50%;transform-origin:33.33333333% 50%}.tippy-popper[x-placement^=left] .tippy-roundarrow svg{position:absolute;left:0;-webkit-transform:rotate(90deg);transform:rotate(90deg)}.tippy-popper[x-placement^=left] .tippy-arrow{border-left:8px solid #333;border-top:8px solid transparent;border-bottom:8px solid transparent;right:-7px;margin:3px 0;-webkit-transform-origin:0 50%;transform-origin:0 50%}.tippy-popper[x-placement^=left] .tippy-backdrop{-webkit-transform-origin:50% 0;transform-origin:50% 0}.tippy-popper[x-placement^=left] .tippy-backdrop[data-state=visible]{-webkit-transform:scale(1) translate(-50%,-50%);transform:scale(1) translate(-50%,-50%)}.tippy-popper[x-placement^=left] .tippy-backdrop[data-state=hidden]{-webkit-transform:scale(.2) translate(-75%,-50%);transform:scale(.2) translate(-75%,-50%);opacity:0}.tippy-popper[x-placement^=left] [data-animation=shift-toward][data-state=visible]{-webkit-transform:translateX(-10px);transform:translateX(-10px)}.tippy-popper[x-placement^=left] [data-animation=shift-toward][data-state=hidden]{opacity:0;-webkit-transform:translateX(-20px);transform:translateX(-20px)}.tippy-popper[x-placement^=left] [data-animation=perspective]{-webkit-transform-origin:right;transform-origin:right}.tippy-popper[x-placement^=left] [data-animation=perspective][data-state=visible]{-webkit-transform:translateX(-10px) rotateY(0);transform:translateX(-10px) rotateY(0)}.tippy-popper[x-placement^=left] [data-animation=perspective][data-state=hidden]{opacity:0;-webkit-transform:translateX(0) rotateY(-60deg);transform:translateX(0) rotateY(-60deg)}.tippy-popper[x-placement^=left] [data-animation=fade][data-state=visible]{-webkit-transform:translateX(-10px);transform:translateX(-10px)}.tippy-popper[x-placement^=left] [data-animation=fade][data-state=hidden]{opacity:0;-webkit-transform:translateX(-10px);transform:translateX(-10px)}.tippy-popper[x-placement^=left] [data-animation=shift-away][data-state=visible]{-webkit-transform:translateX(-10px);transform:translateX(-10px)}.tippy-popper[x-placement^=left] [data-animation=shift-away][data-state=hidden]{opacity:0;-webkit-transform:translateX(0);transform:translateX(0)}.tippy-popper[x-placement^=left] [data-animation=scale][data-state=visible]{-webkit-transform:translateX(-10px) scale(1);transform:translateX(-10px) scale(1)}.tippy-popper[x-placement^=left] [data-animation=scale][data-state=hidden]{opacity:0;-webkit-transform:translateX(0) scale(.5);transform:translateX(0) scale(.5)}.tippy-popper[x-placement^=right] .tippy-backdrop{border-radius:0 50% 50% 0}.tippy-popper[x-placement^=right] .tippy-roundarrow{left:-16px;-webkit-transform-origin:66.66666666% 50%;transform-origin:66.66666666% 50%}.tippy-popper[x-placement^=right] .tippy-roundarrow svg{position:absolute;left:0;-webkit-transform:rotate(-90deg);transform:rotate(-90deg)}.tippy-popper[x-placement^=right] .tippy-arrow{border-right:8px solid #333;border-top:8px solid transparent;border-bottom:8px solid transparent;left:-7px;margin:3px 0;-webkit-transform-origin:100% 50%;transform-origin:100% 50%}.tippy-popper[x-placement^=right] .tippy-backdrop{-webkit-transform-origin:-50% 0;transform-origin:-50% 0}.tippy-popper[x-placement^=right] .tippy-backdrop[data-state=visible]{-webkit-transform:scale(1) translate(-50%,-50%);transform:scale(1) translate(-50%,-50%)}.tippy-popper[x-placement^=right] .tippy-backdrop[data-state=hidden]{-webkit-transform:scale(.2) translate(-25%,-50%);transform:scale(.2) translate(-25%,-50%);opacity:0}.tippy-popper[x-placement^=right] [data-animation=shift-toward][data-state=visible]{-webkit-transform:translateX(10px);transform:translateX(10px)}.tippy-popper[x-placement^=right] [data-animation=shift-toward][data-state=hidden]{opacity:0;-webkit-transform:translateX(20px);transform:translateX(20px)}.tippy-popper[x-placement^=right] [data-animation=perspective]{-webkit-transform-origin:left;transform-origin:left}.tippy-popper[x-placement^=right] [data-animation=perspective][data-state=visible]{-webkit-transform:translateX(10px) rotateY(0);transform:translateX(10px) rotateY(0)}.tippy-popper[x-placement^=right] [data-animation=perspective][data-state=hidden]{opacity:0;-webkit-transform:translateX(0) rotateY(60deg);transform:translateX(0) rotateY(60deg)}.tippy-popper[x-placement^=right] [data-animation=fade][data-state=visible]{-webkit-transform:translateX(10px);transform:translateX(10px)}.tippy-popper[x-placement^=right] [data-animation=fade][data-state=hidden]{opacity:0;-webkit-transform:translateX(10px);transform:translateX(10px)}.tippy-popper[x-placement^=right] [data-animation=shift-away][data-state=visible]{-webkit-transform:translateX(10px);transform:translateX(10px)}.tippy-popper[x-placement^=right] [data-animation=shift-away][data-state=hidden]{opacity:0;-webkit-transform:translateX(0);transform:translateX(0)}.tippy-popper[x-placement^=right] [data-animation=scale][data-state=visible]{-webkit-transform:translateX(10px) scale(1);transform:translateX(10px) scale(1)}.tippy-popper[x-placement^=right] [data-animation=scale][data-state=hidden]{opacity:0;-webkit-transform:translateX(0) scale(.5);transform:translateX(0) scale(.5)}.tippy-tooltip{position:relative;color:#fff;border-radius:4px;font-size:.9rem;padding:.3rem .6rem;max-width:350px;text-align:center;will-change:transform;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;background-color:#333}.tippy-tooltip[data-size=small]{padding:.2rem .4rem;font-size:.75rem}.tippy-tooltip[data-size=large]{padding:.4rem .8rem;font-size:1rem}.tippy-tooltip[data-animatefill]{overflow:hidden;background-color:transparent}.tippy-tooltip[data-interactive],.tippy-tooltip[data-interactive] path{pointer-events:auto}.tippy-tooltip[data-inertia][data-state=visible]{transition-timing-function:cubic-bezier(.53,2,.36,.85)}.tippy-tooltip[data-inertia][data-state=hidden]{transition-timing-function:ease}.tippy-arrow,.tippy-roundarrow{position:absolute;width:0;height:0}.tippy-roundarrow{width:24px;height:8px;fill:#333;pointer-events:none}.tippy-backdrop{position:absolute;will-change:transform;background-color:#333;border-radius:50%;width:calc(110% + 2rem);left:50%;top:50%;z-index:-1;transition:all cubic-bezier(.46,.1,.52,.98);-webkit-backface-visibility:hidden;backface-visibility:hidden}.tippy-backdrop:after{content:"";float:left;padding-top:100%}.tippy-backdrop+.tippy-content{transition-property:opacity}.tippy-backdrop+.tippy-content[data-state=visible]{opacity:1}.tippy-backdrop+.tippy-content[data-state=hidden]{opacity:0}@media (max-width:360px){.tippy-popper{max-width:96%;max-width:calc(100% - 20px)}}</style><title>database:(type:pfam pf00344) in UniProtKB</title><meta content="IE=edge" http-equiv="X-UA-Compatible"><meta content="width=device-width, initial-scale=1" name="viewport"><link href="https://www.uniprot.org/" rel="home"><link href="https://creativecommons.org/licenses/by/4.0/" rel="license"><link type="image/vnd.microsoft.icon" href="https://www.uniprot.org/favicon.ico" rel="shortcut icon"><link href="./database_(type_pfam pf00344) in UniProtKB_files/uniprot.min.css2019_08" type="text/css" rel="stylesheet"><script type="text/javascript"> | |
| var BASE = '/'; | |
| var ua = window.navigator.userAgent; | |
| var directory = (~ua.indexOf('MSIE ') || ~ua.indexOf('Trident/')) === 0 ? "non-ie" : "ie"; | |
| </script><style></style><script src="./database_(type_pfam pf00344) in UniProtKB_files/d3.v3.min.js" type="text/javascript"></script><script src="./database_(type_pfam pf00344) in UniProtKB_files/js-compr.js2019_08" type="text/javascript"></script><script type="text/javascript"> | |
| uniprot.namespace = 'uniprot'; | |
| uniprot.releasedate = '2019_08'; | |
| </script><script type="text/javascript"> | |
| ; | |
| </script><link href="https://www.uniprot.org/uniprot/opensearch.xml" title="UniProtKB" type="application/opensearchdescription+xml" rel="search"><script type="text/javascript"> | |
| var resultsize = 40814; | |
| var resultsPage = true; | |
| </script><link href="https://www.uniprot.org/uniprot/?query=database%3a(type%3apfam+pf00344)&sort=score&offset=0&limit=10&format=rss" type="application/rss+xml" title="RSS" rel="alternate"><meta content="noindex,follow" name="robots"><link href="https://www.uniprot.org/uniprot/?query=database%3a(type%3apfam+pf00344)&offset=10&sort=score" rel="next"><meta content="nositelinkssearchbox" name="google"><script type="text/javascript" src="./database_(type_pfam pf00344) in UniProtKB_files/common-bundle.js"></script><script type="text/javascript" src="./database_(type_pfam pf00344) in UniProtKB_files/uniprot_results-bundle.js"></script></head><body class="namespace-uniprot hasGoogleVoiceExt" typeof="WebPage" prefix="up: http://purl.uniprot.org/core/" vocab="http://schema.org/"><span id="evidenceToolTip" style="display:none"> | |
| <p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.</p> | |
| <p><a href="/manual/evidences">More...</a></p> | |
| </span> | |
| <!--[if lte IE 8]> | |
| <style type="text/css"> | |
| #browserwarning { | |
| display:block; | |
| }; | |
| </style> | |
| <![endif]--> | |
| <p style="display:none"><a accesskey="2" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#content">Skip Header</a></p><div id="masthead-container"><div class="masthead" id="local-masthead"><div id="local-title"><a id="logo" accesskey="1" href="https://www.uniprot.org/"><img alt="" src="./database_(type_pfam pf00344) in UniProtKB_files/Logo_medium.png" title="UniProt home"></a></div><div class="namespace-uniprot" id="local-search"><form method="get" action="https://www.uniprot.org/uniprot" id="search-form"><div id="namespace-background"><div class="searchBoxIndicator" style="display:none" id="searchBoxIndicator1"> </div><div onclick="location.href='/help/text-search';" class="searchBoxIndicator" style="display:none" id="searchBoxIndicator2"> </div><div onclick="location.href='/help/advanced_search ';" class="searchBoxIndicator" style="display:none" id="searchBoxIndicator3"> </div><a class="namespace-select" id="select-namespace" onclick="return false;" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score"><span class="caret_white" id="selected-namespace">UniProtKB</span></a><ul style="display:none" class="select-namespace-options"><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" class="closeBox" id="closeNamespaceOptions">x</a><li><ul><li class="fixedHeight_namespaces"><h3 class="namespace_uniprot"><a class="namespace-option uniprot" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="uniprot">UniProtKB</a></h3><p>Protein knowledgebase</p></li><li class="fixedHeight_namespaces"><h3 class="namespace_uniparc"><a class="namespace-option uniparc" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="uniparc">UniParc</a></h3><p>Sequence archive</p></li><li class="fixedHeight_namespaces"><h3 class="namespace_help"><a class="namespace-option help" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="help">Help</a></h3><p>Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.</p></li></ul></li><li><ul><li class="fixedHeight_namespaces"><h3 class="namespace_uniref"><a class="namespace-option uniref" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="uniref">UniRef</a></h3><p>Sequence clusters</p></li><li class="fixedHeight_namespaces"><h3 class="namespace_proteomes"><a class="namespace-option proteomes" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="proteomes">Proteomes</a></h3><p>Protein sets from fully sequenced genomes</p></li><li class="fixedHeight_namespaces"><h3 class="namespace_unirule">Annotation systems</h3><p class="supportingLeadingText">Systems used to automatically annotate proteins with high accuracy:</p><ul class="supportingDataOptions"><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="unirule">UniRule (Expertly curated rules)</a></li><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="saas">SAAS (System generated rules)</a></li></ul></li></ul></li><li><ul><li class="fixedHeight_namespaces"><h3 class="supporting"><span>Supporting data</span></h3><p class="supportingLeadingText">Select one of the options below to target your search:</p><ul class="supportingDataOptions"><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="citations">Literature citations</a></li><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="taxonomy">Taxonomy</a></li><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="keywords">Keywords</a></li><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="locations">Subcellular locations</a></li><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="database">Cross-referenced databases</a></li><li><a class="namespace-option supporting" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="diseases">Human diseases</a></li></ul></li></ul></li></ul><input value="database:(type:pfam pf00344)" id="topQuery" type="hidden"><div id="queryContainer"><input autocomplete="off" autofocus="autofocus" id="query" value="database:(type:pfam pf00344)" accesskey="4" name="query" type="search"> | |
| <div class="tree-select-menu" id="q0"> | |
| <div class="tree-select"> | |
| <ul></ul> | |
| </div> | |
| </div> | |
| </div><a class="caret_grey" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" id="advanced-search-toggle">Advanced</a><input value="score" name="sort" type="hidden"><a id="search-button" title="Search" data-icon="1" class="icon icon-functional button">Search</a><div style="display:none" class="advSearch" id="query-builder-container"><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" class="closeBox" id="closeAdvanceSearch">x</a><div id="advanced-search"></div></div></div></form></div><div id="nav"><ul id="local-nav"><li class="mobileHomeLink"><a href="https://www.uniprot.org/">Home</a></li><li class="first"><a class="tooltipped" title="Find regions of local similarity between sequences" href="https://www.uniprot.org/blast" id="top-blast-link">BLAST</a></li><li><a class="tooltipped" title="Align two or more protein sequences with the Clustal Omega program" href="https://www.uniprot.org/align" accesskey="9" id="top-align-link">Align</a></li><li class="last"><a class="tooltipped" title="Submit a list of identifiers to retrieve the corresponding UniProt entries, or to map them from or to an external database" rel="help" href="https://www.uniprot.org/uploadlists" id="upload-lists-nav">Retrieve/ID mapping</a></li><li class="last"><a class="tooltipped" title="Submit a list of peptides to find UniProt sequences containing them" rel="help" href="https://www.uniprot.org/peptidesearch" id="peptidesearch-lists-nav">Peptide search</a></li><li class="functional last"><a accesskey="9" href="https://www.uniprot.org/contact" id="contact">Contact</a></li><li class="functional"><a rel="help" href="https://www.uniprot.org/help/" id="help">Help</a></li></ul></div></div></div><div class="warn" id="browserwarning">You are using a version of browser that may not display all the features of this website. Please consider upgrading <a href="https://www.uniprot.org/help/browser_support">your browser</a>.</div><main class="uniprot" property="schema:mainEntity" resource="#{typeof}" typeof="Dataset" id="content"><section id="page-header"><div><div style="display:none" id="customizeColumns" class="newCustomize"><h2 class="page-title">Customize results table</h2><div style="display:none" id="forcedColumnsArea"><div class="customise-header-container"><h4><a target="_blank" href="https://www.uniprot.org/help/customize">Unsaved columns<sup>i</sup></a></h4></div><p>Click on the <span class="add"> </span>to add to <span>'Columns to be displayed'</span> and to the <span>'Miscellaneous'</span> section below for future use.</p><ul class="ui-sortable" id="forcedColumns"></ul></div><div class="customise-header-container" id="selectedColumnsArea"><h4><a target="_blank" href="https://www.uniprot.org/help/customize">Columns to be displayed<sup>i</sup></a></h4><ul id="topCustomizeActionButtons" class="customizeSettings"><li><button class="columnsResetToDefaults" id="top-columnsResetToDefaults">Reset to <i>default</i></button></li><li><button class="customize-columns-save button" id="top-customize-columns-save">Save</button></li><li><button class="customize-columns-cancel button" id="top-customize-columns-cancel">Cancel</button></li></ul></div><p>Drag and drop to re-order.</p><ul class="ui-sortable" id="selectedColumns"><li class="selectedColumn ui-content ui-state-default static" id="id-column-input-selected"><span>Entry</span></li></ul><div class="clearfix"></div><div><div class="customise-header-container"><h4><a target="_blank" href="https://www.uniprot.org/help/customize">Add more columns<sup>i</sup></a></h4><ul class="customizeSettings"><li id="expand_all"><a data-icon="9" class="icon icon-functional" id="expandAllHeaders" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#">Expand all</a></li><li data-icon="8" class="icon icon-functional" style="display:none" id="collapse_all"><a id="collapseAllHeaders" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#">Collapse all</a></li></ul></div><div id="customise-search-wrap"><div id="customise-search">Search: <input title="e.g. gene, ontology,..." name="customizeSearch" id="customizeSearch" type="text" autocomplete="off"> | |
| <div class="tree-select-menu" id="q1"> | |
| <div class="tree-select"> | |
| <ul></ul> | |
| </div> | |
| </div> | |
| </div></div><div class="clearfix"></div><div id="customize-columns-choices"><div class="customizeRow"><div class="customizeField names_and_taxonomy"><a class="icon icon-functional expandableLink expandableHeader" data-icon="8">Names & Taxonomy</a><div class="foldable"><ul><li><input id="entry_name-column-input" type="checkbox" class="defaultColumn"><span>Entry name</span></li><li><input id="genes-column-input" type="checkbox" checked="checked" class="defaultColumn"><span>Gene names</span></li><li><input id="genes_8_OLN_9_-column-input" type="checkbox" checked="checked"><span>Gene names (ordered locus)</span></li><li><input id="genes_8_ORF_9_-column-input" type="checkbox" checked="checked"><span>Gene names (ORF)</span></li><li><input id="genes_8_PREFERRED_9_-column-input" type="checkbox" checked="checked"><span>Gene names (primary)</span></li><li><input id="genes_8_ALTERNATIVE_9_-column-input" type="checkbox" checked="checked"><span>Gene names (synonym)</span></li><li><input id="organism-column-input" type="checkbox" checked="checked" class="defaultColumn"><span>Organism</span></li><li><input id="organism-id-column-input" type="checkbox"><span>Organism ID</span></li><li><input id="protein_names-column-input" type="checkbox" checked="checked" class="defaultColumn"><span>Protein names</span></li><li><input id="proteome-column-input" type="checkbox"><span>Proteomes</span></li><li><input id="lineage_8_ALL_9_-column-input" type="checkbox"><span>Taxonomic lineage</span></li><li><input id="virus_hosts-column-input" type="checkbox"><span>Virus hosts</span></li></ul></div></div><div class="customizeField sequences"><a class="icon icon-functional expandableLink expandableHeader" data-icon="8">Sequences</a><div class="foldable"><ul><li><input id="comment_8_ALTERNATIVE_PRODUCTS_9_-column-input" type="checkbox"><span>Alternative products (isoforms) </span></li><li><input id="feature_8_ALTERNATIVE_SEQUENCE_9_-column-input" type="checkbox"><span>Alternative sequence </span></li><li><input id="comment_8_ERRONEOUS_GENE_MODEL_PREDICTION_9_-column-input" type="checkbox"><span>Erroneous gene model prediction </span></li><li><input id="fragment-column-input" type="checkbox"><span>Fragment</span></li><li><input id="encodedon-column-input" type="checkbox"><span>Gene encoded by</span></li><li><input id="length-column-input" type="checkbox" checked="checked" class="defaultColumn"><span>Length</span></li><li><input id="mass-column-input" type="checkbox"><span>Mass</span></li><li><input id="comment_8_MASS_SPECTROMETRY_9_-column-input" type="checkbox"><span>Mass spectrometry </span></li><li><input id="feature_8_NATURAL_VARIANT_9_-column-input" type="checkbox"><span>Natural variant </span></li><li><input id="feature_8_NON_ADJACENT_RESIDUES_9_-column-input" type="checkbox"><span>Non-adjacent residues </span></li><li><input id="feature_8_NON_STANDARD_RESIDUE_9_-column-input" type="checkbox"><span>Non-standard residue </span></li><li><input id="feature_8_NON_TERMINAL_RESIDUE_9_-column-input" type="checkbox"><span>Non-terminal residue </span></li><li><input id="comment_8_POLYMORPHISM_9_-column-input" type="checkbox"><span>Polymorphism </span></li><li><input id="comment_8_RNA_EDITING_9_-column-input" type="checkbox"><span>RNA editing </span></li><li><input id="sequence-column-input" type="checkbox"><span>Sequence</span></li><li><input id="comment_8_SEQUENCE_CAUTION_9_-column-input" type="checkbox"><span>Sequence caution </span></li><li><input id="feature_8_SEQUENCE_CONFLICT_9_-column-input" type="checkbox"><span>Sequence conflict </span></li><li><input id="feature_8_SEQUENCE_UNCERTAINTY_9_-column-input" type="checkbox"><span>Sequence uncertainty </span></li><li><input id="version_8_sequence_9_-column-input" type="checkbox" checked="checked"><span>Sequence version</span></li></ul></div></div><div class="customizeField function"><a class="icon icon-functional expandableLink expandableHeader" data-icon="8">Function</a><div class="foldable"><ul><li><input id="comment_8_ABSORPTION_9_-column-input" type="checkbox"><span>Absorption </span></li><li><input id="feature_8_ACTIVE_SITE_9_-column-input" type="checkbox"><span>Active site </span></li><li><input id="comment_8_ACTIVITY_REGULATION_9_-column-input" type="checkbox"><span>Activity regulation </span></li><li><input id="feature_8_BINDING_SITE_9_-column-input" type="checkbox"><span>Binding site </span></li><li><input id="feature_8_CALCIUM_BIND_9_-column-input" type="checkbox"><span>Calcium binding </span></li><li><input id="comment_8_CATALYTIC_ACTIVITY_9_-column-input" type="checkbox"><span>Catalytic activity </span></li><li><input id="comment_8_COFACTOR_9_-column-input" type="checkbox"><span>Cofactor </span></li><li><input id="feature_8_DNA_BINDING_9_-column-input" type="checkbox"><span>DNA binding </span></li><li><input id="ec-column-input" type="checkbox"><span>EC number</span></li><li><input id="comment_8_FUNCTION_9_-column-input" type="checkbox"><span>Function </span><span class="context-help tooltipped-click html tipId-0" tabindex="0"><span style="display:none"><span class="toolTipContent"> | |
| <p>Position-independent general annotations used to be found in the 'General annotation (Comments)' section in the previous version of the UniProtKB entry view. They provide any useful information about the protein, mostly biological knowledge. General annotations are frequently written in free text, although we increasingly try to standardize them and use controlled vocabulary wherever possible. The flat file and XML formats still group all general annotation together in a "Comments section" (CC, <comment>). <p><a href='/help/general_annotation' target='_top'>More...</a></p></span></span>[CC]<sup>i</sup></span></li><li><input id="comment_8_KINETICS_9_-column-input" type="checkbox"><span>Kinetics </span></li><li><input id="feature_8_METAL_BINDING_9_-column-input" type="checkbox"><span>Metal binding </span></li><li><input id="feature_8_NP_BIND_9_-column-input" type="checkbox"><span>Nucleotide binding </span></li><li><input id="comment_8_PATHWAY_9_-column-input" type="checkbox"><span>Pathway </span></li><li><input id="comment_8_PH_DEPENDENCE_9_-column-input" type="checkbox"><span>pH dependence </span></li><li><input id="comment_8_REDOX_POTENTIAL_9_-column-input" type="checkbox"><span>Redox potential </span></li><li><input id="rhea-id-column-input" type="checkbox"><span>Rhea Ids</span></li><li><input id="feature_8_SITE_9_-column-input" type="checkbox"><span>Site </span></li><li><input id="comment_8_TEMPERATURE_DEPENDENCE_9_-column-input" type="checkbox"><span>Temperature dependence </span></li></ul></div></div><div class="customizeField miscellaneous"><a class="icon icon-functional expandableLink expandableHeader" data-icon="8">Miscellaneous</a><div class="foldable"><ul><li><input id="annotation_score-column-input" type="checkbox"><span>Annotation</span></li><li><input id="comment_8_CAUTION_9_-column-input" type="checkbox"><span>Caution </span></li><li><input id="features-column-input" type="checkbox"><span>Features</span></li><li><input id="isomap_8_M201910026746803381A1F0E0DB47453E0216320DC4813AT_9_-column-input" type="checkbox"><span>Isoform map:M20191002..4813AT</span></li><li><input id="keyword-id-column-input" type="checkbox"><span>Keyword ID</span></li><li><input id="keywords-column-input" type="checkbox"><span>Keywords</span></li><li><input id="context-column-input" type="checkbox"><span>Matched text</span></li><li><input id="comment_8_MISCELLANEOUS_9_-column-input" type="checkbox"><span>Miscellaneous </span><span class="context-help tooltipped-click html tipId-0" tabindex="0">[CC]<sup>i</sup></span></li><li><input id="existence-column-input" type="checkbox"><span>Protein existence</span></li><li><input id="reviewed-column-input" class="defaultColumn" type="checkbox" checked="checked"><span class="icon-uniprot reviewed-icon tooltipped" data-icon="s" title="Reviewed (Swiss-Prot)"></span><span class="icon-uniprot unreviewed-icon tooltipped" data-icon="t" title="Unreviewed (TrEMBL)"></span></li><li><input id="tools-column-input" type="checkbox"><span>Tools</span></li><li><input id="uniparcid-column-input" type="checkbox"><span>UniParc</span></li><li><input id="yourlist_8_M201910026746803381A1F0E0DB47453E0216320DC4813AT_9_-column-input" type="checkbox"><span>Your list:M20191002..4813AT</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField interaction"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Interaction</a><div class="foldable" style="display:none"><ul><li><input id="interactor-column-input" type="checkbox"><span>Interacts with</span></li><li><input id="comment_8_SUBUNIT_STRUCTURE_9_-column-input" type="checkbox"><span>Subunit structure </span><span class="context-help tooltipped-click html tipId-0" tabindex="0">[CC]<sup>i</sup></span></li></ul></div></div><div class="customizeField expression"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Expression</a><div class="foldable" style="display:none"><ul><li><input id="comment_8_DEVELOPMENTAL_STAGE_9_-column-input" type="checkbox"><span>Developmental stage </span></li><li><input id="comment_8_INDUCTION_9_-column-input" type="checkbox"><span>Induction </span></li><li><input id="comment_8_TISSUE_SPECIFICITY_9_-column-input" type="checkbox"><span>Tissue specificity </span></li></ul></div></div><div class="customizeField gene_ontology"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Gene Ontology (GO)</a><div class="foldable" style="display:none"><ul><li><input id="go_8_biological_process_9_-column-input" type="checkbox"><span>Gene ontology (biological process)</span></li><li><input id="go_8_cellular_component_9_-column-input" type="checkbox"><span>Gene ontology (cellular component)</span></li><li><input id="go-column-input" type="checkbox"><span>Gene ontology (GO)</span></li><li><input id="go_8_molecular_function_9_-column-input" type="checkbox"><span>Gene ontology (molecular function)</span></li><li><input id="go-id-column-input" type="checkbox"><span>Gene ontology IDs</span></li></ul></div></div><div class="customizeField chemical_entities"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Chemical entities (ChEBI)</a><div class="foldable" style="display:none"><ul><li><input id="chebi-column-input" type="checkbox"><span>ChEBI</span></li><li><input id="chebi_8_Catalytic_activity_9_-column-input" type="checkbox"><span>ChEBI (Catalytic activity)</span></li><li><input id="chebi_8_Cofactor_9_-column-input" type="checkbox"><span>ChEBI (Cofactor)</span></li><li><input id="chebi-id-column-input" type="checkbox"><span>ChEBI IDs</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField pathology_and_biotech"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Pathology & Biotech</a><div class="foldable" style="display:none"><ul><li><input id="comment_8_ALLERGENIC_PROPERTIES_9_-column-input" type="checkbox"><span>Allergenic properties </span></li><li><input id="comment_8_BIOTECHNOLOGICAL_USE_9_-column-input" type="checkbox"><span>Biotechnological use </span></li><li><input id="comment_8_DISRUPTION_PHENOTYPE_9_-column-input" type="checkbox"><span>Disruption phenotype </span></li><li><input id="comment_8_INVOLVEMENT_IN_DISEASE_9_-column-input" type="checkbox"><span>Involvement in disease </span></li><li><input id="feature_8_MUTAGENESIS_9_-column-input" type="checkbox"><span>Mutagenesis </span></li><li><input id="comment_8_PHARMACEUTICAL_USE_9_-column-input" type="checkbox"><span>Pharmaceutical use </span></li><li><input id="comment_8_TOXIC_DOSE_9_-column-input" type="checkbox"><span>Toxic dose </span></li></ul></div></div><div class="customizeField subcellular_location"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Subcellular location</a><div class="foldable" style="display:none"><ul><li><input id="feature_8_INTRAMEMBRANE_9_-column-input" type="checkbox"><span>Intramembrane </span></li><li><input id="comment_8_SUBCELLULAR_LOCATION_9_-column-input" type="checkbox"><span>Subcellular location </span><span class="context-help tooltipped-click html tipId-0" tabindex="0">[CC]<sup>i</sup></span></li><li><input id="feature_8_TOPOLOGICAL_DOMAIN_9_-column-input" type="checkbox"><span>Topological domain </span></li><li><input id="feature_8_TRANSMEMBRANE_9_-column-input" type="checkbox"><span>Transmembrane </span></li></ul></div></div><div class="customizeField ptm_or_processing"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">PTM / Processsing</a><div class="foldable" style="display:none"><ul><li><input id="feature_8_CHAIN_9_-column-input" type="checkbox"><span>Chain </span></li><li><input id="feature_8_CROSS_LINK_9_-column-input" type="checkbox"><span>Cross-link </span></li><li><input id="feature_8_DISULFIDE_BOND_9_-column-input" type="checkbox"><span>Disulfide bond </span></li><li><input id="feature_8_GLYCOSYLATION_9_-column-input" type="checkbox"><span>Glycosylation </span></li><li><input id="feature_8_INITIATOR_METHIONINE_9_-column-input" type="checkbox"><span>Initiator methionine </span></li><li><input id="feature_8_LIPIDATION_9_-column-input" type="checkbox"><span>Lipidation </span></li><li><input id="feature_8_MODIFIED_RESIDUE_9_-column-input" type="checkbox"><span>Modified residue </span></li><li><input id="feature_8_PEPTIDE_9_-column-input" type="checkbox"><span>Peptide </span></li><li><input id="comment_8_POST-TRANSLATIONAL_MODIFICATION_9_-column-input" type="checkbox"><span>Post-translational modification </span></li><li><input id="feature_8_PROPEPTIDE_9_-column-input" type="checkbox"><span>Propeptide </span></li><li><input id="feature_8_SIGNAL_9_-column-input" type="checkbox"><span>Signal peptide </span></li><li><input id="feature_8_TRANSIT_9_-column-input" type="checkbox"><span>Transit peptide </span></li></ul></div></div><div class="customizeField structure"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Structure</a><div class="foldable" style="display:none"><ul><li><input id="3d-column-input" type="checkbox"><span>3D</span></li><li><input id="feature_8_BETA_STRAND_9_-column-input" type="checkbox"><span>Beta strand </span></li><li><input id="feature_8_HELIX_9_-column-input" type="checkbox"><span>Helix </span></li><li><input id="feature_8_TURN_9_-column-input" type="checkbox"><span>Turn </span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField publications"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Publications</a><div class="foldable" style="display:none"><ul><li><input id="citationmapping-column-input" type="checkbox"><span>Mapped PubMed ID</span></li><li><input id="citation-column-input" type="checkbox"><span>PubMed ID</span></li></ul></div></div><div class="customizeField date_of"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Date of</a><div class="foldable" style="display:none"><ul><li><input id="created-column-input" type="checkbox"><span>Date of creation</span></li><li><input id="last-modified-column-input" type="checkbox"><span>Date of last modification</span></li><li><input id="sequence-modified-column-input" type="checkbox"><span>Date of last sequence modification</span></li><li><input id="version_8_entry_9_-column-input" type="checkbox" checked="checked"><span>Entry version</span></li></ul></div></div><div class="customizeField family_and_domain"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Family & Domains</a><div class="foldable" style="display:none"><ul><li><input id="feature_8_COILED_COIL_9_-column-input" type="checkbox"><span>Coiled coil </span></li><li><input id="feature_8_COMPOSITIONAL_BIAS_9_-column-input" type="checkbox"><span>Compositional bias </span></li><li><input id="comment_8_DOMAIN_9_-column-input" type="checkbox"><span>Domain </span><span class="context-help tooltipped-click html tipId-0" tabindex="0">[CC]<sup>i</sup></span></li><li><input id="feature_8_DOMAIN_EXTENT_9_-column-input" type="checkbox"><span>Domain </span><span class="context-help tooltipped-click html tipId-1" tabindex="0"><span style="display:none"><span class="toolTipContent"> | |
| <p>Sequence annotations describe regions or sites of interest in the protein sequence, such as post-translational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. Sequence conflicts between references are also described in this manner.<p><a href='/help/sequence_annotation' target='_top'>More...</a></p></span></span>[FT]<sup>i</sup></span></li><li><input id="feature_8_MOTIF_9_-column-input" type="checkbox"><span>Motif </span></li><li><input id="families-column-input" type="checkbox"><span>Protein families</span></li><li><input id="feature_8_REGION_9_-column-input" type="checkbox"><span>Region </span></li><li><input id="feature_8_REPEAT_9_-column-input" type="checkbox"><span>Repeat </span></li><li><input id="comment_8_SEQUENCE_SIMILARITIES_9_-column-input" type="checkbox"><span>Sequence similarities </span></li><li><input id="feature_8_ZINC_FINGER_9_-column-input" type="checkbox"><span>Zinc finger </span></li></ul></div></div><div class="customizeField tax_lineage"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Taxonomic lineage</a><div class="foldable" style="display:none"><ul><li><input id="lineage_8_all_9_-column-input" type="checkbox"><span>Taxonomic lineage (all)</span></li><li><input id="lineage_8_CLASS_9_-column-input" type="checkbox"><span>Taxonomic lineage (CLASS)</span></li><li><input id="lineage_8_COHORT_9_-column-input" type="checkbox"><span>Taxonomic lineage (COHORT)</span></li><li><input id="lineage_8_FAMILY_9_-column-input" type="checkbox"><span>Taxonomic lineage (FAMILY)</span></li><li><input id="lineage_8_FORMA_9_-column-input" type="checkbox"><span>Taxonomic lineage (FORMA)</span></li><li><input id="lineage_8_GENUS_9_-column-input" type="checkbox"><span>Taxonomic lineage (GENUS)</span></li><li><input id="lineage_8_INFRACLASS_9_-column-input" type="checkbox"><span>Taxonomic lineage (INFRACLASS)</span></li><li><input id="lineage_8_INFRAORDER_9_-column-input" type="checkbox"><span>Taxonomic lineage (INFRAORDER)</span></li><li><input id="lineage_8_KINGDOM_9_-column-input" type="checkbox"><span>Taxonomic lineage (KINGDOM)</span></li><li><input id="lineage_8_ORDER_9_-column-input" type="checkbox"><span>Taxonomic lineage (ORDER)</span></li><li><input id="lineage_8_PARVORDER_9_-column-input" type="checkbox"><span>Taxonomic lineage (PARVORDER)</span></li><li><input id="lineage_8_PHYLUM_9_-column-input" type="checkbox"><span>Taxonomic lineage (PHYLUM)</span></li><li><input id="lineage_8_SPECIES_9_-column-input" type="checkbox"><span>Taxonomic lineage (SPECIES)</span></li><li><input id="lineage_8_SPECIES_GROUP_9_-column-input" type="checkbox"><span>Taxonomic lineage (SPECIES_GROUP)</span></li><li><input id="lineage_8_SPECIES_SUBGROUP_9_-column-input" type="checkbox"><span>Taxonomic lineage (SPECIES_SUBGROUP)</span></li><li><input id="lineage_8_SUBCLASS_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBCLASS)</span></li><li><input id="lineage_8_SUBCOHORT_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBCOHORT)</span></li><li><input id="lineage_8_SUBFAMILY_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBFAMILY)</span></li><li><input id="lineage_8_SUBGENUS_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBGENUS)</span></li><li><input id="lineage_8_SUBKINGDOM_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBKINGDOM)</span></li><li><input id="lineage_8_SUBORDER_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBORDER)</span></li><li><input id="lineage_8_SUBPHYLUM_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBPHYLUM)</span></li><li><input id="lineage_8_SUBSPECIES_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBSPECIES)</span></li><li><input id="lineage_8_SUBTRIBE_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUBTRIBE)</span></li><li><input id="lineage_8_SUPERCLASS_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUPERCLASS)</span></li><li><input id="lineage_8_SUPERFAMILY_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUPERFAMILY)</span></li><li><input id="lineage_8_SUPERKINGDOM_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUPERKINGDOM)</span></li><li><input id="lineage_8_SUPERORDER_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUPERORDER)</span></li><li><input id="lineage_8_SUPERPHYLUM_9_-column-input" type="checkbox"><span>Taxonomic lineage (SUPERPHYLUM)</span></li><li><input id="lineage_8_TRIBE_9_-column-input" type="checkbox"><span>Taxonomic lineage (TRIBE)</span></li><li><input id="lineage_8_VARIETAS_9_-column-input" type="checkbox"><span>Taxonomic lineage (VARIETAS)</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField tax_id"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Taxonomic identifier</a><div class="foldable" style="display:none"><ul><li><input id="lineage-id-column-input" type="checkbox" checked="checked"><span>Taxonomic lineage IDs</span></li></ul></div></div></div><div class="customize-databases-header"><h4>Databases</h4></div><div class="customizeRow"><div class="customizeField sequence"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Sequence</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_CCDS_9_-column-input"><span>CCDS</span></li><li><input type="checkbox" id="database_8_EMBL_9_-column-input"><span>EMBL</span></li><li><input type="checkbox" id="database_8_PIR_9_-column-input"><span>PIR</span></li><li><input type="checkbox" id="database_8_RefSeq_9_-column-input"><span>RefSeq</span></li></ul></div></div><div class="customizeField structure"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">3D structure</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_PDB_9_-column-input"><span>PDB</span></li><li><input type="checkbox" id="database_8_PDBsum_9_-column-input"><span>PDBsum</span></li><li><input type="checkbox" id="database_8_SMR_9_-column-input"><span>SMR</span></li></ul></div></div><div class="customizeField interaction"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Protein-protein interaction</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_BioGrid_9_-column-input"><span>BioGrid</span></li><li><input type="checkbox" id="database_8_ComplexPortal_9_-column-input"><span>ComplexPortal</span></li><li><input type="checkbox" id="database_8_CORUM_9_-column-input"><span>CORUM</span></li><li><input type="checkbox" id="database_8_DIP_9_-column-input"><span>DIP</span></li><li><input type="checkbox" id="database_8_ELM_9_-column-input"><span>ELM</span></li><li><input type="checkbox" id="database_8_IntAct_9_-column-input"><span>IntAct</span></li><li><input type="checkbox" id="database_8_MINT_9_-column-input"><span>MINT</span></li><li><input type="checkbox" id="database_8_STRING_9_-column-input"><span>STRING</span></li></ul></div></div><div class="customizeField chemistry"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Chemistry</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_BindingDB_9_-column-input"><span>BindingDB</span></li><li><input type="checkbox" id="database_8_ChEMBL_9_-column-input"><span>ChEMBL</span></li><li><input type="checkbox" id="database_8_DrugBank_9_-column-input"><span>DrugBank</span></li><li><input type="checkbox" id="database_8_DrugCentral_9_-column-input"><span>DrugCentral</span></li><li><input type="checkbox" id="database_8_GuidetoPHARMACOLOGY_9_-column-input"><span>GuidetoPHARMACOLOGY</span></li><li><input type="checkbox" id="database_8_SwissLipids_9_-column-input"><span>SwissLipids</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField family"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Protein family/group</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_Allergome_9_-column-input"><span>Allergome</span></li><li><input type="checkbox" id="database_8_CAZy_9_-column-input"><span>CAZy</span></li><li><input type="checkbox" id="database_8_ESTHER_9_-column-input"><span>ESTHER</span></li><li><input type="checkbox" id="database_8_IMGT_GENE-DB_9_-column-input"><span>IMGT_GENE-DB</span></li><li><input type="checkbox" id="database_8_MEROPS_9_-column-input"><span>MEROPS</span></li><li><input type="checkbox" id="database_8_MoonDB_9_-column-input"><span>MoonDB</span></li><li><input type="checkbox" id="database_8_MoonProt_9_-column-input"><span>MoonProt</span></li><li><input type="checkbox" id="database_8_mycoCLAP_9_-column-input"><span>mycoCLAP</span></li><li><input type="checkbox" id="database_8_PeroxiBase_9_-column-input"><span>PeroxiBase</span></li><li><input type="checkbox" id="database_8_REBASE_9_-column-input"><span>REBASE</span></li><li><input type="checkbox" id="database_8_TCDB_9_-column-input"><span>TCDB</span></li><li><input type="checkbox" id="database_8_UniLectin_9_-column-input"><span>UniLectin</span></li></ul></div></div><div class="customizeField ptm"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">PTM</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_CarbonylDB_9_-column-input"><span>CarbonylDB</span></li><li><input type="checkbox" id="database_8_DEPOD_9_-column-input"><span>DEPOD</span></li><li><input type="checkbox" id="database_8_GlyConnect_9_-column-input"><span>GlyConnect</span></li><li><input type="checkbox" id="database_8_iPTMnet_9_-column-input"><span>iPTMnet</span></li><li><input type="checkbox" id="database_8_PhosphoSitePlus_9_-column-input"><span>PhosphoSitePlus</span></li><li><input type="checkbox" id="database_8_SwissPalm_9_-column-input"><span>SwissPalm</span></li><li><input type="checkbox" id="database_8_UniCarbKB_9_-column-input"><span>UniCarbKB</span></li></ul></div></div><div class="customizeField polymorphism"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Polymorphism and mutation</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_BioMuta_9_-column-input"><span>BioMuta</span></li><li><input type="checkbox" id="database_8_dbSNP_9_-column-input"><span>dbSNP</span></li><li><input type="checkbox" id="database_8_DMDM_9_-column-input"><span>DMDM</span></li></ul></div></div><div class="customizeField gel"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">2D gel</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_COMPLUYEAST-2DPAGE_9_-column-input"><span>COMPLUYEAST-2DPAGE</span></li><li><input type="checkbox" id="database_8_DOSAC-COBS-2DPAGE_9_-column-input"><span>DOSAC-COBS-2DPAGE</span></li><li><input type="checkbox" id="database_8_OGP_9_-column-input"><span>OGP</span></li><li><input type="checkbox" id="database_8_REPRODUCTION-2DPAGE_9_-column-input"><span>REPRODUCTION-2DPAGE</span></li><li><input type="checkbox" id="database_8_SWISS-2DPAGE_9_-column-input"><span>SWISS-2DPAGE</span></li><li><input type="checkbox" id="database_8_UCD-2DPAGE_9_-column-input"><span>UCD-2DPAGE</span></li><li><input type="checkbox" id="database_8_World-2DPAGE_9_-column-input"><span>World-2DPAGE</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField proteomic"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Proteomic</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_CPTAC_9_-column-input"><span>CPTAC</span></li><li><input type="checkbox" id="database_8_EPD_9_-column-input"><span>EPD</span></li><li><input type="checkbox" id="database_8_jPOST_9_-column-input"><span>jPOST</span></li><li><input type="checkbox" id="database_8_MassIVE_9_-column-input"><span>MassIVE</span></li><li><input type="checkbox" id="database_8_MaxQB_9_-column-input"><span>MaxQB</span></li><li><input type="checkbox" id="database_8_PaxDb_9_-column-input"><span>PaxDb</span></li><li><input type="checkbox" id="database_8_PeptideAtlas_9_-column-input"><span>PeptideAtlas</span></li><li><input type="checkbox" id="database_8_PRIDE_9_-column-input"><span>PRIDE</span></li><li><input type="checkbox" id="database_8_ProMEX_9_-column-input"><span>ProMEX</span></li><li><input type="checkbox" id="database_8_ProteomicsDB_9_-column-input"><span>ProteomicsDB</span></li><li><input type="checkbox" id="database_8_TopDownProteomics_9_-column-input"><span>TopDownProteomics</span></li></ul></div></div><div class="customizeField protocol"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Protocols and materials</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_ABCD_9_-column-input"><span>ABCD</span></li><li><input type="checkbox" id="database_8_DNASU_9_-column-input"><span>DNASU</span></li></ul></div></div><div class="customizeField genome"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Genome annotation</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_Ensembl_9_-column-input"><span>Ensembl</span></li><li><input type="checkbox" id="database_8_EnsemblBacteria_9_-column-input"><span>EnsemblBacteria</span></li><li><input type="checkbox" id="database_8_EnsemblFungi_9_-column-input"><span>EnsemblFungi</span></li><li><input type="checkbox" id="database_8_EnsemblMetazoa_9_-column-input"><span>EnsemblMetazoa</span></li><li><input type="checkbox" id="database_8_EnsemblPlants_9_-column-input"><span>EnsemblPlants</span></li><li><input type="checkbox" id="database_8_EnsemblProtists_9_-column-input"><span>EnsemblProtists</span></li><li><input type="checkbox" id="database_8_GeneDB_9_-column-input"><span>GeneDB</span></li><li><input type="checkbox" id="database_8_GeneID_9_-column-input"><span>GeneID</span></li><li><input type="checkbox" id="database_8_Gramene_9_-column-input"><span>Gramene</span></li><li><input type="checkbox" id="database_8_KEGG_9_-column-input"><span>KEGG</span></li><li><input type="checkbox" id="database_8_PATRIC_9_-column-input"><span>PATRIC</span></li><li><input type="checkbox" id="database_8_UCSC_9_-column-input"><span>UCSC</span></li><li><input type="checkbox" id="database_8_VectorBase_9_-column-input"><span>VectorBase</span></li><li><input type="checkbox" id="database_8_WBParaSite_9_-column-input"><span>WBParaSite</span></li></ul></div></div><div class="customizeField organism"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Organism-specific</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_ArachnoServer_9_-column-input"><span>ArachnoServer</span></li><li><input type="checkbox" id="database_8_Araport_9_-column-input"><span>Araport</span></li><li><input type="checkbox" id="database_8_CGD_9_-column-input"><span>CGD</span></li><li><input type="checkbox" id="database_8_ConoServer_9_-column-input"><span>ConoServer</span></li><li><input type="checkbox" id="database_8_CTD_9_-column-input"><span>CTD</span></li><li><input type="checkbox" id="database_8_dictyBase_9_-column-input"><span>dictyBase</span></li><li><input type="checkbox" id="database_8_DisGeNET_9_-column-input"><span>DisGeNET</span></li><li><input type="checkbox" id="database_8_EchoBASE_9_-column-input"><span>EchoBASE</span></li><li><input type="checkbox" id="database_8_EcoGene_9_-column-input"><span>EcoGene</span></li><li><input type="checkbox" id="database_8_euHCVdb_9_-column-input"><span>euHCVdb</span></li><li><input type="checkbox" id="database_8_EuPathDB_9_-column-input"><span>EuPathDB</span></li><li><input type="checkbox" id="database_8_FlyBase_9_-column-input"><span>FlyBase</span></li><li><input type="checkbox" id="database_8_GeneCards_9_-column-input"><span>GeneCards</span></li><li><input type="checkbox" id="database_8_GeneReviews_9_-column-input"><span>GeneReviews</span></li><li><input type="checkbox" id="database_8_HGNC_9_-column-input"><span>HGNC</span></li><li><input type="checkbox" id="database_8_HPA_9_-column-input"><span>HPA</span></li><li><input type="checkbox" id="database_8_LegioList_9_-column-input"><span>LegioList</span></li><li><input type="checkbox" id="database_8_Leproma_9_-column-input"><span>Leproma</span></li><li><input type="checkbox" id="database_8_MaizeGDB_9_-column-input"><span>MaizeGDB</span></li><li><input type="checkbox" id="database_8_MalaCards_9_-column-input"><span>MalaCards</span></li><li><input type="checkbox" id="database_8_MGI_9_-column-input"><span>MGI</span></li><li><input type="checkbox" id="database_8_MIM_9_-column-input"><span>MIM</span></li><li><input type="checkbox" id="database_8_neXtProt_9_-column-input"><span>neXtProt</span></li><li><input type="checkbox" id="database_8_NIAGADS_9_-column-input"><span>NIAGADS</span></li><li><input type="checkbox" id="database_8_OpenTargets_9_-column-input"><span>OpenTargets</span></li><li><input type="checkbox" id="database_8_Orphanet_9_-column-input"><span>Orphanet</span></li><li><input type="checkbox" id="database_8_PharmGKB_9_-column-input"><span>PharmGKB</span></li><li><input type="checkbox" id="database_8_PomBase_9_-column-input"><span>PomBase</span></li><li><input type="checkbox" id="database_8_PseudoCAP_9_-column-input"><span>PseudoCAP</span></li><li><input type="checkbox" id="database_8_RGD_9_-column-input"><span>RGD</span></li><li><input type="checkbox" id="database_8_SGD_9_-column-input"><span>SGD</span></li><li><input type="checkbox" id="database_8_TAIR_9_-column-input"><span>TAIR</span></li><li><input type="checkbox" id="database_8_TubercuList_9_-column-input"><span>TubercuList</span></li><li><input type="checkbox" id="database_8_VGNC_9_-column-input"><span>VGNC</span></li><li><input type="checkbox" id="database_8_WormBase_9_-column-input"><span>WormBase</span></li><li><input type="checkbox" id="database_8_Xenbase_9_-column-input"><span>Xenbase</span></li><li><input type="checkbox" id="database_8_ZFIN_9_-column-input"><span>ZFIN</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField phylogenomic"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Phylogenomic</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_eggNOG_9_-column-input"><span>eggNOG</span></li><li><input type="checkbox" id="database_8_GeneTree_9_-column-input"><span>GeneTree</span></li><li><input type="checkbox" id="database_8_HOGENOM_9_-column-input"><span>HOGENOM</span></li><li><input type="checkbox" id="database_8_InParanoid_9_-column-input"><span>InParanoid</span></li><li><input type="checkbox" id="database_8_KO_9_-column-input"><span>KO</span></li><li><input type="checkbox" id="database_8_OMA_9_-column-input"><span>OMA</span></li><li><input type="checkbox" id="database_8_OrthoDB_9_-column-input"><span>OrthoDB</span></li><li><input type="checkbox" id="database_8_PhylomeDB_9_-column-input"><span>PhylomeDB</span></li><li><input type="checkbox" id="database_8_TreeFam_9_-column-input"><span>TreeFam</span></li></ul></div></div><div class="customizeField pathway"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Enzyme and pathway</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_BioCyc_9_-column-input"><span>BioCyc</span></li><li><input type="checkbox" id="database_8_BRENDA_9_-column-input"><span>BRENDA</span></li><li><input type="checkbox" id="database_8_Reactome_9_-column-input"><span>Reactome</span></li><li><input type="checkbox" id="database_8_SABIO-RK_9_-column-input"><span>SABIO-RK</span></li><li><input type="checkbox" id="database_8_SignaLink_9_-column-input"><span>SignaLink</span></li><li><input type="checkbox" id="database_8_SIGNOR_9_-column-input"><span>SIGNOR</span></li><li><input type="checkbox" id="database_8_UniPathway_9_-column-input"><span>UniPathway</span></li></ul></div></div><div class="customizeField other"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Other</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_ChiTaRS_9_-column-input"><span>ChiTaRS</span></li><li><input type="checkbox" id="database_8_EvolutionaryTrace_9_-column-input"><span>EvolutionaryTrace</span></li><li><input type="checkbox" id="database_8_GeneWiki_9_-column-input"><span>GeneWiki</span></li><li><input type="checkbox" id="database_8_GenomeRNAi_9_-column-input"><span>GenomeRNAi</span></li><li><input type="checkbox" id="database_8_Pharos_9_-column-input"><span>Pharos</span></li><li><input type="checkbox" id="database_8_PMAP-CutDB_9_-column-input"><span>PMAP-CutDB</span></li><li><input type="checkbox" id="database_8_PRO_9_-column-input"><span>PRO</span></li></ul></div></div><div class="customizeField expression"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Gene expression</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_Bgee_9_-column-input"><span>Bgee</span></li><li><input type="checkbox" id="database_8_CollecTF_9_-column-input"><span>CollecTF</span></li><li><input type="checkbox" id="database_8_ExpressionAtlas_9_-column-input"><span>ExpressionAtlas</span></li><li><input type="checkbox" id="database_8_Genevisible_9_-column-input"><span>Genevisible</span></li></ul></div></div></div><div class="customizeRow"><div class="customizeField domain"><a class="icon icon-functional expandableLink expandableHeader" data-icon="9">Family and domain</a><div class="foldable" style="display:none"><ul><li><input type="checkbox" id="database_8_CDD_9_-column-input"><span>CDD</span></li><li><input type="checkbox" id="database_8_DisProt_9_-column-input"><span>DisProt</span></li><li><input type="checkbox" id="database_8_Gene3D_9_-column-input"><span>Gene3D</span></li><li><input type="checkbox" id="database_8_HAMAP_9_-column-input"><span>HAMAP</span></li><li><input type="checkbox" id="database_8_InterPro_9_-column-input"><span>InterPro</span></li><li><input type="checkbox" id="database_8_PANTHER_9_-column-input"><span>PANTHER</span></li><li><input type="checkbox" id="database_8_Pfam_9_-column-input"><span>Pfam</span></li><li><input type="checkbox" id="database_8_PIRSF_9_-column-input"><span>PIRSF</span></li><li><input type="checkbox" id="database_8_PRINTS_9_-column-input"><span>PRINTS</span></li><li><input type="checkbox" id="database_8_PROSITE_9_-column-input"><span>PROSITE</span></li><li><input type="checkbox" id="database_8_SFLD_9_-column-input"><span>SFLD</span></li><li><input type="checkbox" id="database_8_SMART_9_-column-input"><span>SMART</span></li><li><input type="checkbox" id="database_8_SUPFAM_9_-column-input"><span>SUPFAM</span></li><li><input type="checkbox" id="database_8_TIGRFAMs_9_-column-input"><span>TIGRFAMs</span></li></ul></div></div></div><script type="text/javascript">uniprot.defaultColumns=['id','entry_name','reviewed','protein_names','genes','organism','length'];</script></div><div id="customizeList"></div></div><ul id="bottomCustomizeActionButtons" class="customizeSettings"><li><button class="columnsResetToDefaults" id="top-columnsResetToDefaults">Reset to <i>default</i></button></li><li><button class="customize-columns-save button" id="bottom-customize-columns-save">Save</button></li><li><button class="customize-columns-cancel button" id="bottom-customize-columns-cancel">Cancel</button></li></ul></div></div><h2 class="page-title displayThis">UniProtKB results</h2><div id="top-right-actions"><a data-icon="?" class="icon icon-generic" id="showHelp" style="display: none;">About UniProtKB</a><div style="" id="basket"><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#" data-icon="b" class="closed basket-empty icon icon-static caret_white button" id="basket-list">Basket <span style="display:none" id="basket-count">0</span></a></div><div style="z-index: 3;display:none" id="basket-contents"><div id="closeBasket"><span class="basketText">(max 400 entries)</span><button class="closeBox">x</button></div><div id="emptyBasketContent"><h3><span class="context-help tooltipped-click" tabindex="0"> | |
| Your basket is currently empty. <sup> i</sup><span style="display:none"><span class="toolTipContent"> | |
| <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.</p><p><a href="https://www.uniprot.org/help/basket" target="_top">More...</a></p></span></span></span></h3><p>Select item(s) and click on "Add to basket" to create your own collection here<br> (400 entries max)<br></p><div id="emptyBasketContentHelp"></div></div><div style="display:none" id="loadingBasketContent"></div><div id="filledBasketContents"><ul id="basketTabs" class="tabs"><li><a id="uniprotBasketTab" class="uniprot tab basketTab">UniProtKB (<span class="uniprot-basket-count">0</span>)</a></li><li><a id="unirefBasketTab" class="uniref tab basketTab">UniRef (<span class="uniref-basket-count">0</span>)</a></li><li><a id="uniparcBasketTab" class="uniparc tab basketTab">UniParc (<span class="uniparc-basket-count">0</span>)</a></li></ul><div class="tabsContent" style="display: none" id="basket-uniprot"></div><div class="tabsContent" style="display: none" id="basket-uniref"></div><div class="tabsContent" style="display: none" id="basket-uniparc"></div></div><div id="basket-actions"><div class="action-buttons-grouped"><button title="Select two or more entries and click here to align them" data-icon="i" class="button icon icon-functional align disabled" id="basket-align-button">Align</button><button data-icon="t" title="Select an entry and click here to run a BLAST search on it" class="button icon-functional icon blast disabled" id="basket-blast-button">BLAST</button><button title="Map ids to other databases" class="button icon-functional disabled" id="basket-map-button">Map Ids</button><button data-icon="=" title="Download results" class="button icon icon-functional download disabled" id="basket-download-button">Download</button><span class="icon-right"><button title="Full View" class="button fullView disabled" id="basket-view-button">Full View</button><button title="Remove Selected entries" class="button remove disabled" id="basket-remove-button">Remove</button><button title="Clear basket" class="button clear disabled" id="basket-clear-button">Clear</button></span></div></div></div><form action="https://www.uniprot.org/align/" method="post" id="basket-alignForm"><input value="no" name="landingPage" type="hidden"><input value="clustalo" name="program" type="hidden"><input value="yes" name="redirect" type="hidden"><input value="" name="alignQuery" id="basket-alignQuery" type="hidden"></form><form action="https://www.uniprot.org/blast/" method="post" id="basket-blastForm"><input value="yes" name="redirect" type="hidden"><input value="no" name="landingPage" type="hidden"><input value="uniprotkb_refprotswissprot" name="dataset" type="hidden"><input value="10" name="threshold" type="hidden"><input value="" name="matrix" type="hidden"><input value="false" name="filter" type="hidden"><input value="true" name="gapped" type="hidden"><input value="250" name="numal" type="hidden"><input value="" id="basket-blastQuery" name="blastQuery" type="hidden"></form><form action="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score" method="post" id="basket-downloadForm"><input value="" name="query" type="hidden"></form></div><div style="" class="helpcontent" id="help-uniprot"><button class="closeBox" id="closeHelp">x</button><div class="helpBoxContainer"><div class="helpBoxPanel subheading"><h5>UniProtKB consists of two sections:</h5></div><div class="helpBoxPanel"><p><span data-icon="s" class="icon-uniprot reviewed-icon"></span><strong> Reviewed (Swiss-Prot) - Manually annotated</strong><br>Records with information extracted from literature and curator-evaluated computational analysis.</p><p><span data-icon="t" class="icon-uniprot unreviewed-icon"></span><strong> Unreviewed (TrEMBL) - Computationally analyzed</strong><br>Records that await full manual annotation.</p></div></div><div class="helpBoxContainer"><div class="helpBoxPanel"> <br> <br>The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the | |
| core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. | |
| </div><div class="helpLinks"><a data-icon="?" class="icon icon-generic namespaceIcons" href="https://www.uniprot.org/help/uniprotkb">Help</a><a data-icon="V" class="icon icon-generic namespaceIcons" target="_blank" href="https://www.youtube.com/watch?v=ado1r8IDm3U">UniProtKB help video</a><a data-icon="V" class="icon icon-generic namespaceIcons" target="_blank" href="https://www.youtube.com/channel/UCkCR5RJZCZZoVTQzTYY92aw">Other tutorials and videos</a><a data-icon="=" class="icon icon-functional namespaceIcons" href="https://www.uniprot.org/downloads#uniprotkblink">Downloads</a></div></div></div></section> <aside class="sidebar displayThis"><div class="filterBy sidebarsubsection"><h3 class="first context-help tooltipped-click" tabindex="0">Filter by<sup>i</sup><span style="display:none"><span class="toolTipContent"> | |
| <p>A search result page is subdivided into a filter panel on the left, and the actual result table on the right, occupying the majority of the screen space.</p><p><a href="https://www.uniprot.org/help/filter_options" target="_top">More...</a></p></span></span></h3><div class="clearfix"></div><div class="sidebarsubsection"><ul><li><a rel="nofollow" class="icon-uniprot reviewed-icon" id="reviewed-filter" data-icon="s" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=reviewed%3Ayes&sort=score">Reviewed (156)<div class="small">Swiss-Prot</div></a></li><li><a rel="nofollow" class="icon-uniprot unreviewed-icon" id="unreviewed-filter" data-icon="t" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=reviewed%3Ano&sort=score">Unreviewed (40,658)<div class="small">TrEMBL</div></a></li></ul></div><div class="sidebarsubsection"><h4>Popular organisms</h4><div class="suggestionOrganism"><ul><li><a rel="nofollow" class="tooltipped" title="Oryza sativa subsp. japonica" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=organism%3A%22Oryza+sativa+subsp.+japonica+%28Rice%29+%5B39947%5D%22&sort=score" id="orgFilter-39947">Rice (21)</a></li><li><a rel="nofollow" class="tooltipped" title="Homo sapiens" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=organism%3A%22Homo+sapiens+%28Human%29+%5B9606%5D%22&sort=score" id="orgFilter-9606">Human (19)</a></li><li><a rel="nofollow" class="tooltipped" title="Arabidopsis thaliana" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=organism%3A%22Arabidopsis+thaliana+%28Mouse-ear+cress%29+%5B3702%5D%22&sort=score" id="orgFilter-3702">A. thaliana (13)</a></li><li><a rel="nofollow" class="tooltipped" title="Mus musculus" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=organism%3A%22Mus+musculus+%28Mouse%29+%5B10090%5D%22&sort=score" id="orgFilter-10090">Mouse (7)</a></li><li><a rel="nofollow" class="tooltipped" title="Bos taurus" href="https://www.uniprot.org/uniprot/?query=database:(type:pfam%20pf00344)&fil=organism%3A%22Bos+taurus+%28Bovine%29+%5B9913%5D%22&sort=score" id="orgFilter-9913">Bovine (6)</a></li></ul><div class="otherOrgs"><div class="advanced-search-inputs"><label>Other organisms</label><input size="9" id="orgName" style="display:inline" autocomplete="off"><div class="tree-select-menu" id="otherorgsuggestiontree" style="z-index:10"><div class="tree-select"><ul></ul></div></div><a id="orgFind" class="button">Go</a></div></div></div></div></div><div class="viewBy sidebarsubsection"><h3>View by</h3><ul class="viewByList"><li class="viewByParent active-filter"><a rel="nofollow" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score" class="viewBy" id="tableViewBy">Results table</a></li><li id="orgViewByParent" class="viewByParent"><a rel="nofollow" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#orgViewBy" class="viewBy">Taxonomy</a></li><li id="keyViewByParent" class="viewByParent"><a rel="nofollow" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#keyViewBy" class="viewBy">Keywords</a></li><li id="goViewByParent" class="viewByParent"><a rel="nofollow" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#goViewBy" class="viewBy">Gene Ontology</a></li><li id="enzymesViewByParent" class="viewByParent"><a rel="nofollow" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#enzymesViewBy" class="viewBy">Enzyme class</a></li><li id="pathwaysViewByParent" class="viewByParent"><a rel="nofollow" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#pathwaysViewBy" class="viewBy">Pathway</a></li></ul></div><div class="redundancy sidebarsubsection"><h3 title="The UniProt Reference Clusters (UniRef) provide clustered sets of sequences from the UniProtKB (including isoforms) and selected UniParc records" class="tooltipped">UniRef</h3>Your results in sequence clusters with identity of:<br><span><a title="UniRef100" rel="nofollow" class="tooltipped" href="https://www.uniprot.org/uniref/?query=uniprot:(database%3A%28type%3Apfam+pf00344%29)+identity:1.0">100%</a>, | |
| <a title="UniRef90" rel="nofollow" class="tooltipped" href="https://www.uniprot.org/uniref/?query=uniprot:(database%3A%28type%3Apfam+pf00344%29)+identity:0.9">90%</a> or | |
| <a title="UniRef50" rel="nofollow" class="tooltipped" href="https://www.uniprot.org/uniref/?query=uniprot:(database%3A%28type%3Apfam+pf00344%29)+identity:0.5">50%</a></span></div><div class=" sidebarsubsection mousePointer"><h3>Demo</h3><a target="_blank" href="https://www.youtube.com/watch?v=ado1r8IDm3U"><span data-icon="V" class="icon icon-generic helpVideo"> </span><span class="helpVideoText">Help video</span></a></div></aside><div class="main-aside"><script type="text/javascript"> | |
| uniprot.resultsize = 40814; | |
| uniprot.sort = 'score'; | |
| uniprot.columns = 'id,organism,protein names,genes,length,database(Pfam),database(InterPro),lineage-id,comment(SUBCELLULAR LOCATION),feature(SIGNAL),feature(TRANSIT),feature(TOPOLOGICAL DOMAIN),feature(TRANSMEMBRANE),feature(INTRAMEMBRANE),comment(SEQUENCE CAUTION),comment(CAUTION),lineage(SUPERKINGDOM),lineage(KINGDOM),lineage(PHYLUM),database(RefSeq),database(EMBL)'; | |
| uniprot.columns = uniprot.columns.replace(new RegExp('_', 'g'), ' '); | |
| uniprot.desc = !true ? 'no' : ''; | |
| uniprot.isMappingJobPresent = false; | |
| </script><span class="status"><span title="previous page" class="prevPageButton prevPageButtonGreyed"></span><strong> 1</strong> to <strong> | |
| 10 | |
| </strong> | |
| of <strong class="queryResultCount">40,814</strong> | |
| <a class="nextPageLink" href="https://www.uniprot.org/uniprot?query=database%3a(type%3apfam+pf00344)&offset=10&sort=score"><span title="next page" class="nextPageButton"></span></a><span class="statusShow">Show | |
| <select name="limit" class="limitdropDown"><option name="10" selected="selected">10</option><option name="25">25</option><option name="50">50</option><option name="100">100</option><option name="250">250</option></select></span></span><div id="resultActionButtons" class="action-buttons-grouped decorated"><button data-icon="t" class="icon icon-functional button disabled tooltipped" data-tippy="BLAST against UniProtKB" id="blast-button">BLAST</button><button data-icon="i" class="icon icon-functional button disabled tooltipped" data-tippy="Select two or more entries and click here to align them" id="align-button">Align</button><button data-icon="=" class="icon icon-functional button tooltipped" data-tippy="Download results" onclick="return false;" id="download-button">Download</button><form action="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score" method="get" id="downloadForm"><input id="selectedQuery" value="database:(type:pfam pf00344)" type="hidden" name="query"><input id="selectedFormat" value="html" type="hidden" name="format"><input id="selectedForce" value="false" type="hidden" name="force"><input value="score" type="hidden" name="sort"><input value="true" type="hidden" name="desc"><input id="selectedFilter" value="" type="hidden" name="fil"><input id="selectedInclude" value="false" type="hidden" name="include"><input value="id,organism,protein names,genes,length,database(Pfam),database(InterPro),lineage-id,comment(SUBCELLULAR LOCATION),feature(SIGNAL),feature(TRANSIT),feature(TOPOLOGICAL DOMAIN),feature(TRANSMEMBRANE),feature(INTRAMEMBRANE),comment(SEQUENCE CAUTION),comment(CAUTION),lineage(SUPERKINGDOM),lineage(KINGDOM),lineage(PHYLUM),database(RefSeq),database(EMBL)" type="hidden" name="columns"></form><button data-icon="b" class="icon icon-static button tooltipped disabled" data-tippy="Select entries and click here to save them to your basket (400 entries max)" id="add-basket-button">Add to basket</button><a data-icon="e" class="icon icon-functional button tooltipped" data-tippy="Add or remove columns from the results table" id="customize-columns-button" href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+PF00344%29&sort=score#customize-columns">Columns</a><button data-icon="d" class="icon icon-generic button tooltipped" data-tippy="Share link to your results" id="share-results-button"></button><span id="shareTooltipContent" style="display:none"><span style="display:none"><span class="toolTipContent"> | |
| <p>The ‘Share’ button allows you to share a custom URL including the columns in your result view.</p> | |
| <p><a href="/help/api_queries">More...</a></p> | |
| </span></span></span></div><form action="https://www.uniprot.org/align/" method="post" id="alignForm"><input value="no" name="landingPage" type="hidden"><input value="clustalo" name="program" type="hidden"><input value="yes" name="redirect" type="hidden"><input value="" name="alignQuery" id="alignQuery" type="hidden"></form><form action="https://www.uniprot.org/blast/" method="post" id="blastForm"><input value="yes" name="redirect" type="hidden"><input value="no" name="landingPage" type="hidden"><input value="uniprotkb_refprotswissprot" name="dataset" type="hidden"><input value="10" name="threshold" type="hidden"><input value="" name="matrix" type="hidden"><input value="false" name="filter" type="hidden"><input value="true" name="gapped" type="hidden"><input value="250" name="numal" type="hidden"><input value="" id="blastQuery" name="blastQuery" type="hidden"></form><form action="https://www.uniprot.org/uploadlists/" method="post" id="uploadForm"><input value="yes" name="landingPage" type="hidden"><input value="" id="uploadQuery" name="uploadQuery" type="hidden"></form><h2 class="page-title printThis">UniProtKB Results</h2><div class="content results"><div style="display:none" id="viewByCanvas"><h4 id="vb_namespace"></h4><div class="viewBy-search-area"><label for="query_viewBy">Search:</label><input id="query_viewBy" type="text" autocomplete="off"><div id="viewbysuggestiontree" class="tree-select-menu"><div class="tree-select"><ul></ul></div></div></div><div id="viewByArea"><div id="viewByTree"><ul class="TreeView" id="treeView"> </ul><div style="display:none" id="loader_tree"></div></div><div id="viewByGraphContainer"><div style="display:none" id="loader_graph"></div><div id="viewByGraph"><svg width="800" height="500" class="svgViewBy"></svg></div></div></div></div><div id="resultsArea"><form><table class="grid" id="results"><thead><tr><th><input id="selectAll-resultSet" type="checkbox"></th><th><span id="idHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Unique and stable entry identifier</p> </div>" tabindex="0">Entry</span><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+pf00344%29&sort=id&desc=no"><div class="icon_sort_none" title="Sort A-Z" alt="Sort A-Z"></div></a></span></span></th><th><span id="organismHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Scientific name (and synonyms) of the source organism " tabindex="0">Organism</span><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+pf00344%29&sort=organism&desc=no"><div class="icon_sort_none" title="Sort A-Z" alt="Sort A-Z"></div></a></span></span></th><th><span id="protein_namesHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Name(s) and synonym(s) of the protein " tabindex="0">Protein names</span><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+pf00344%29&sort=protein_names&desc=no"><div class="icon_sort_none" title="Sort A-Z" alt="Sort A-Z"></div></a></span><span class="expander"><div class="long icon_collapse" title="Collapse this column into smaller text" style="display:none;"></div><div class="short icon_expand" title="Expand this column into longer text"></div></span></span></th><th><span id="genesHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Name(s) of the gene(s) encoding the protein " tabindex="0">Gene names</span><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+pf00344%29&sort=genes&desc=no"><div class="icon_sort_none" title="Sort A-Z" alt="Sort A-Z"></div></a></span></span></th><th><span id="lengthHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Length of the canonical sequence</p> </div>" tabindex="0">Length</span><a href="https://www.uniprot.org/uniprot/?query=database%3A%28type%3Apfam+pf00344%29&sort=length"><div class="icon_sort_none" title="Sort Z-A" alt="Sort Z-A"></div></a></span></span></th><th><span id="databaseHeader"><span class="expanderHeading">Cross-reference (Pfam)</span></span></th><th><span id="databaseHeader"><span class="expanderHeading">Cross-reference (InterPro)</span></span></th><th><span id="lineage-idHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Hierarchical classification of the source organism " tabindex="0">Taxonomic lineage IDs</span></span></span></th><th><span id="commentHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Sequence position-independent annotation (comments) " tabindex="0">Subcellular location [CC]</span></span></span></th><th><span id="featureHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Extent of the sequence targeting proteins to the secretory pathway or periplasmic space " tabindex="0">Signal peptide</span></span></span></th><th><span id="featureHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Extent of a transit peptide for organelle targeting " tabindex="0">Transit peptide</span></span></span></th><th><span id="featureHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Sequence position-dependent annotation (features) " tabindex="0">Topological domain</span></span></span></th><th><span id="featureHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Description of the extent of a membrane-spanning region of the protein " tabindex="0">Transmembrane</span></span></span></th><th><span id="featureHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Extent of a region in a membrane, which does not cross it " tabindex="0">Intramembrane</span></span></span></th><th><span id="commentHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Sequence position-independent annotation (comments) " tabindex="0">Sequence caution</span></span></span></th><th><span id="commentHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Warning about possible errors and/or grounds for confusion " tabindex="0">Caution</span></span></span></th><th><span id="lineageHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Hierarchical classification of the source organism " tabindex="0">Taxonomic lineage (SUPERKINGDOM)</span></span></span></th><th><span id="lineageHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Hierarchical classification of the source organism " tabindex="0">Taxonomic lineage (KINGDOM)</span></span></span></th><th><span id="lineageHeader"><span class="expanderHeading"><span class="toolTipContent" data-tippy="<div> <p>Hierarchical classification of the source organism " tabindex="0">Taxonomic lineage (PHYLUM)</span></span></span></th><th><span id="databaseHeader"><span class="expanderHeading">Cross-reference (RefSeq)</span></span></th><th><span id="databaseHeader"><span class="expanderHeading">Cross-reference (EMBL)</span></span></th><th title="Add or remove columns from the results table" class="addRemoveColumn tooltipped">e</th></tr><tr style="display:none" id="selectAllStatus"><td colspan="23"><div class="result-status" id="selectAll-resultStatus"></div></td></tr></thead><tbody><tr id="P0AGA2" class=" entry selected-row"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_P0AGA2" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/P0AGA2">P0AGA2</a></td><td><a href="https://www.uniprot.org/taxonomy/83333">Escherichia coli (strain K12)</a></td><td><div class="protein_names"><div class="short" title="Protein translocase subunit SecY"><strong>Protein translocase subunit SecY</strong></div><div class="long" style="display:none;"><strong>Protein translocase subunit SecY</strong></div></div></td><td><div class="gene-names"><span class="shortName"><strong>secY</strong> prlA, b3300, JW3262 </span></div></td><td class="number">443</td><td><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/P0AGA2" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR026593">IPR026593</a> SecY<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/protein/P0AGA2" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/83333">83333</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0037">Cell inner membrane </a><a class="icon icon-generic tooltipped" data-tippy="The prokaryotic inner cell membrane is the selectively permeable membrane which separates the cytoplasm from the periplasm in prokaryotes with 2 membranes." data-icon="i" tabindex="0"></a>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a></li></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[1-22]&key=Topological%20domain">1 – 22</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">22</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[36-60]&key=Topological%20domain">36 – 60</a></td><td class="featdescription"><span property="text">Periplasmic</span><span class="attribution ECO250"><span class="attributionHeader tooltipped" title="Manual assertion inferred from sequence similarity">By similarity</span></span></td><td></td><td class="featlength numeric">25</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[97-115]&key=Topological%20domain">97 – 115</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">19</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[132-164]&key=Topological%20domain">132 – 164</a></td><td class="featdescription"><span property="text">Periplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">33</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[179-183]&key=Topological%20domain">179 – 183</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">5</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[201-223]&key=Topological%20domain">201 – 223</a></td><td class="featdescription"><span property="text">Periplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[238-273]&key=Topological%20domain">238 – 273</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">36</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[288-313]&key=Topological%20domain">288 – 313</a></td><td class="featdescription"><span property="text">Periplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">26</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[330-380]&key=Topological%20domain">330 – 380</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">51</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[396]&key=Topological%20domain">396</a></td><td class="featdescription"><span property="text">Periplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">1</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[414-443]&key=Topological%20domain">414 – 443</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">30</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[23-35]&key=Transmembrane">23 – 35</a></td><td class="featdescription"><span property="text">Helical; Name=1</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">13</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[61-96]&key=Transmembrane">61 – 96</a></td><td class="featdescription"><span property="text">Discontinuously helical; Name=2</span><span class="attribution ECO250"><span class="attributionHeader tooltipped" title="Manual assertion inferred from sequence similarity">By similarity</span></span></td><td></td><td class="featlength numeric">36</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[116-131]&key=Transmembrane">116 – 131</a></td><td class="featdescription"><span property="text">Helical; Name=3</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">16</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[165-178]&key=Transmembrane">165 – 178</a></td><td class="featdescription"><span property="text">Helical; Name=4</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">14</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[184-200]&key=Transmembrane">184 – 200</a></td><td class="featdescription"><span property="text">Helical; Name=5</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">17</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[224-237]&key=Transmembrane">224 – 237</a></td><td class="featdescription"><span property="text">Helical; Name=6</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">14</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[274-287]&key=Transmembrane">274 – 287</a></td><td class="featdescription"><span property="text">Helical; Name=7</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">14</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[314-329]&key=Transmembrane">314 – 329</a></td><td class="featdescription"><span property="text">Helical; Name=8</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">16</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[381-395]&key=Transmembrane">381 – 395</a></td><td class="featdescription"><span property="text">Helical; Name=9</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">15</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[397-413]&key=Transmembrane">397 – 413</a></td><td class="featdescription"><span property="text">Helical; Name=10</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">17</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[61-70]&key=Intramembrane">61 – 70</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 2A</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">10</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[71-76]&key=Intramembrane">71 – 76</a></td><td class="featdescription"><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">6</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P0AGA2[77-96]&key=Intramembrane">77 – 96</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 2B</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">20</td></tr></tbody></table></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2">Bacteria</a></td><td></td><td><a href="https://www.uniprot.org/taxonomy/1224">Proteobacteria</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_417759.1">NP_417759.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NC_000913.3">NC_000913.3</a><br><a href="https://www.ncbi.nlm.nih.gov/protein/WP_001118861.1">WP_001118861.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NZ_STEB01000038.1">NZ_STEB01000038.1</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/X01563" class="embl">X01563</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/CAA25725" class="embl_cds">CAA25725.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/U18997" class="embl">U18997</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAA58097" class="embl_cds">AAA58097.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/U00096" class="embl">U00096</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAC76325" class="embl_cds">AAC76325.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AP009048" class="embl">AP009048</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAE77991" class="embl_cds">BAE77991.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="P61619" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_P61619" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/P61619">P61619</a></td><td><a href="https://www.uniprot.org/taxonomy/9606">Homo sapiens (Human)</a></td><td><div class="protein_names"><div class="short" title="Protein transport protein Sec61 subunit alpha isoform 1"><strong>Protein transport protein Sec61 sub...</strong></div><div class="long" style="display:none;"><strong>Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1</strong></div></div></td><td><div class="gene-names"><span class="shortName"><strong>SEC61A1</strong> SEC61A </span></div></td><td class="number">476</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/P61619" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/P61619" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/9606">9606</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0097">Endoplasmic reticulum membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding the endoplasmic reticulum (ER). The endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0"><span style="display:none"><span class="toolTipContent"> | |
| <p>Manually curated information for which there is published experimental evidence.</p> | |
| <p><a href="/manual/evidences#ECO:0000269">More...</a></p> | |
| </span></span>Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="P61619#ref11 referenceAttribution"><div class="reference_header">Ref.11</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/27392076" typeof="ScholarlyArticle"><strong property="name">"Heterozygous loss-of-function SEC61A1 mutations cause autosomal-dominant tubulo-interstitial and glomerulocystic kidney disease with anemia."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Bolar+N.A.%22&sort=score" rel="nofollow">Bolar N.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Golzio+C.%22&sort=score" rel="nofollow">Golzio C.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Zivna+M.%22&sort=score" rel="nofollow">Zivna M.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hayot+G.%22&sort=score" rel="nofollow">Hayot G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Van+Hemelrijk+C.%22&sort=score" rel="nofollow">Van Hemelrijk C.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Schepers+D.%22&sort=score" rel="nofollow">Schepers D.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Vandeweyer+G.%22&sort=score" rel="nofollow">Vandeweyer G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hoischen+A.%22&sort=score" rel="nofollow">Hoischen A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Huyghe+J.R.%22&sort=score" rel="nofollow">Huyghe J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Raes+A.%22&sort=score" rel="nofollow">Raes A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Matthys+E.%22&sort=score" rel="nofollow">Matthys E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Sys+E.%22&sort=score" rel="nofollow">Sys E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Azou+M.%22&sort=score" rel="nofollow">Azou M.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Gubler+M.C.%22&sort=score" rel="nofollow">Gubler M.C.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Praet+M.%22&sort=score" rel="nofollow">Praet M.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Van+Camp+G.%22&sort=score" rel="nofollow">Van Camp G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22McFadden+K.%22&sort=score" rel="nofollow">McFadden K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Pediaditakis+I.%22&sort=score" rel="nofollow">Pediaditakis I.</a><span> <div class="clickable authors icon_expand" title="Show all authors"></div><div style="display:none" class="clickable authors icon_collapse" title="Show less authors"></div> </span><span style="display:none" class="moreAuthorsList">, <a href="https://www.uniprot.org/uniprot/?query=author:%22Pristoupilova+A.%22&sort=score" rel="nofollow">Pristoupilova A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hodanova+K.%22&sort=score" rel="nofollow">Hodanova K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Vyletal+P.%22&sort=score" rel="nofollow">Vyletal P.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hartmannova+H.%22&sort=score" rel="nofollow">Hartmannova H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Stranecky+V.%22&sort=score" rel="nofollow">Stranecky V.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hulkova+H.%22&sort=score" rel="nofollow">Hulkova H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Baresova+V.%22&sort=score" rel="nofollow">Baresova V.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Jedlickova+I.%22&sort=score" rel="nofollow">Jedlickova I.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Sovova+J.%22&sort=score" rel="nofollow">Sovova J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hnizda+A.%22&sort=score" rel="nofollow">Hnizda A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Kidd+K.%22&sort=score" rel="nofollow">Kidd K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Bleyer+A.J.%22&sort=score" rel="nofollow">Bleyer A.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Spong+R.S.%22&sort=score" rel="nofollow">Spong R.S.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Vande+Walle+J.%22&sort=score" rel="nofollow">Vande Walle J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Mortier+G.%22&sort=score" rel="nofollow">Mortier G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Brunner+H.%22&sort=score" rel="nofollow">Brunner H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Van+Laer+L.%22&sort=score" rel="nofollow">Van Laer L.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Kmoch+S.%22&sort=score" rel="nofollow">Kmoch S.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Katsanis+N.%22&sort=score" rel="nofollow">Katsanis N.</a>, </span><a href="https://www.uniprot.org/uniprot/?query=author:%22Loeys+B.L.%22&sort=score" rel="nofollow">Loeys B.L.</a><br><a href="http://dx.doi.org/10.1016/j.ajhg.2016.05.028">Am. J. Hum. Genet. 99:174-187(2016)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/27392076">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/27392076">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/27392076">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> VARIANTS HNFJ4 GLY-67 AND ALA-185, CHARACTERIZATION OF VARIANTS HNFJ4 GLY-67 AND ALA-185, INVOLVEMENT IN HNFJ4, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.</div></div></div></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></li><span class="subcellular-note">Note:</span> <span property="text">Localizes exclusively in granular structures in the endoplasmic reticulum (ER).<span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="P61619#ref11 referenceAttribution"><div class="reference_header">Ref.11</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/27392076" typeof="ScholarlyArticle"><strong property="name">"Heterozygous loss-of-function SEC61A1 mutations cause autosomal-dominant tubulo-interstitial and glomerulocystic kidney disease with anemia."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Bolar+N.A.%22&sort=score" rel="nofollow">Bolar N.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Golzio+C.%22&sort=score" rel="nofollow">Golzio C.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Zivna+M.%22&sort=score" rel="nofollow">Zivna M.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hayot+G.%22&sort=score" rel="nofollow">Hayot G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Van+Hemelrijk+C.%22&sort=score" rel="nofollow">Van Hemelrijk C.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Schepers+D.%22&sort=score" rel="nofollow">Schepers D.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Vandeweyer+G.%22&sort=score" rel="nofollow">Vandeweyer G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hoischen+A.%22&sort=score" rel="nofollow">Hoischen A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Huyghe+J.R.%22&sort=score" rel="nofollow">Huyghe J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Raes+A.%22&sort=score" rel="nofollow">Raes A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Matthys+E.%22&sort=score" rel="nofollow">Matthys E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Sys+E.%22&sort=score" rel="nofollow">Sys E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Azou+M.%22&sort=score" rel="nofollow">Azou M.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Gubler+M.C.%22&sort=score" rel="nofollow">Gubler M.C.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Praet+M.%22&sort=score" rel="nofollow">Praet M.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Van+Camp+G.%22&sort=score" rel="nofollow">Van Camp G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22McFadden+K.%22&sort=score" rel="nofollow">McFadden K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Pediaditakis+I.%22&sort=score" rel="nofollow">Pediaditakis I.</a><span> <div class="clickable authors icon_expand" title="Show all authors"></div><div style="display:none" class="clickable authors icon_collapse" title="Show less authors"></div> </span><span style="display:none" class="moreAuthorsList">, <a href="https://www.uniprot.org/uniprot/?query=author:%22Pristoupilova+A.%22&sort=score" rel="nofollow">Pristoupilova A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hodanova+K.%22&sort=score" rel="nofollow">Hodanova K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Vyletal+P.%22&sort=score" rel="nofollow">Vyletal P.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hartmannova+H.%22&sort=score" rel="nofollow">Hartmannova H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Stranecky+V.%22&sort=score" rel="nofollow">Stranecky V.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hulkova+H.%22&sort=score" rel="nofollow">Hulkova H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Baresova+V.%22&sort=score" rel="nofollow">Baresova V.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Jedlickova+I.%22&sort=score" rel="nofollow">Jedlickova I.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Sovova+J.%22&sort=score" rel="nofollow">Sovova J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hnizda+A.%22&sort=score" rel="nofollow">Hnizda A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Kidd+K.%22&sort=score" rel="nofollow">Kidd K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Bleyer+A.J.%22&sort=score" rel="nofollow">Bleyer A.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Spong+R.S.%22&sort=score" rel="nofollow">Spong R.S.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Vande+Walle+J.%22&sort=score" rel="nofollow">Vande Walle J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Mortier+G.%22&sort=score" rel="nofollow">Mortier G.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Brunner+H.%22&sort=score" rel="nofollow">Brunner H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Van+Laer+L.%22&sort=score" rel="nofollow">Van Laer L.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Kmoch+S.%22&sort=score" rel="nofollow">Kmoch S.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Katsanis+N.%22&sort=score" rel="nofollow">Katsanis N.</a>, </span><a href="https://www.uniprot.org/uniprot/?query=author:%22Loeys+B.L.%22&sort=score" rel="nofollow">Loeys B.L.</a><br><a href="http://dx.doi.org/10.1016/j.ajhg.2016.05.028">Am. J. Hum. Genet. 99:174-187(2016)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/27392076">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/27392076">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/27392076">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> VARIANTS HNFJ4 GLY-67 AND ALA-185, CHARACTERIZATION OF VARIANTS HNFJ4 GLY-67 AND ALA-185, INVOLVEMENT IN HNFJ4, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.</div></div></div></li></ul></span></span></span></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[1-33]&key=Topological%20domain">1 – 33</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">33</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[54-76]&key=Topological%20domain">54 – 76</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[97-117]&key=Topological%20domain">97 – 117</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[139-144]&key=Topological%20domain">139 – 144</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">6</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[166-172]&key=Topological%20domain">166 – 172</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">7</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[194-240]&key=Topological%20domain">194 – 240</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">47</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[262-288]&key=Topological%20domain">262 – 288</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">27</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[310-354]&key=Topological%20domain">310 – 354</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[376-420]&key=Topological%20domain">376 – 420</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[442-445]&key=Topological%20domain">442 – 445</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">4</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[463-476]&key=Topological%20domain">463 – 476</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">14</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[34-53]&key=Transmembrane">34 – 53</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[77-96]&key=Transmembrane">77 – 96</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[118-138]&key=Transmembrane">118 – 138</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[145-165]&key=Transmembrane">145 – 165</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[173-193]&key=Transmembrane">173 – 193</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[241-261]&key=Transmembrane">241 – 261</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[289-309]&key=Transmembrane">289 – 309</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[355-375]&key=Transmembrane">355 – 375</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[421-441]&key=Transmembrane">421 – 441</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61619[446-462]&key=Transmembrane">446 – 462</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">17</td></tr></tbody></table></td><td></td><td>The sequence <a href="https://www.ebi.ac.uk/ena/data/view/BAC11283">BAC11283</a> differs from that shown. Reason: Erroneous initiation.<span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span><br>The sequence <a href="https://www.ebi.ac.uk/ena/data/view/BAC11434">BAC11434</a> differs from that shown. Reason: Erroneous initiation.<span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td><span property="text">No experimental confirmation available.</span></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/33208">Metazoa</a></td><td><a href="https://www.uniprot.org/taxonomy/7711">Chordata</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_037468.1">NP_037468.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_013336.3">NM_013336.3</a> [<a href="https://www.uniprot.org/uniprot/P61619#P61619-1">P61619-1</a>]<br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/AF077032" class="embl">AF077032</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAD27765" class="embl_cds">AAD27765.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AF084458" class="embl">AF084458</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAD39847" class="embl_cds">AAD39847.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AF346602" class="embl">AF346602</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAK29083" class="embl_cds">AAK29083.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AK074907" class="embl">AK074907</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAC11283" class="embl_cds">BAC11283.1</a> Different initiation.<br><a href="https://www.ebi.ac.uk/ena/data/view/AK074928" class="embl">AK074928</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAC11298" class="embl_cds">BAC11298.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AK075148" class="embl">AK075148</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAC11434" class="embl_cds">BAC11434.1</a> Different initiation.<br><a href="https://www.ebi.ac.uk/ena/data/view/AL831940" class="embl">AL831940</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/CAD38592" class="embl_cds">CAD38592.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AL832821" class="embl">AL832821</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/CAI46127" class="embl_cds">CAI46127.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="F4IQV7" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_F4IQV7" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/F4IQV7">F4IQV7</a></td><td><a href="https://www.uniprot.org/taxonomy/3702">Arabidopsis thaliana (Mouse-ear cress)</a></td><td><div class="protein_names"><div class="short" title="Preprotein translocase subunit SCY2, chloroplastic"><strong>Preprotein translocase subunit SCY2...</strong></div><div class="long" style="display:none;"><strong>Preprotein translocase subunit SCY2, chloroplastic</strong> (Protein EMBRYO DEFECTIVE 2289) </div></div></td><td><div class="gene-names"><span class="shortName"><strong>SCY2</strong> EMB2289, At2g31530, T9H9.5 </span></div></td><td class="number">575</td><td><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/F4IQV7" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/protein/F4IQV7" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/3702">3702</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0053">chloroplast membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding a chloroplast. Also used when it is not clear in which chloroplast membrane (outer membrane, inner membrane or thylakoid) a protein is found." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="F4IQV7#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/21051552" typeof="ScholarlyArticle"><strong property="name">"Plastids contain a second sec translocase system with essential functions."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Skalitzky+C.A.%22&sort=score" rel="nofollow">Skalitzky C.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Martin+J.R.%22&sort=score" rel="nofollow">Martin J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Harwood+J.H.%22&sort=score" rel="nofollow">Harwood J.H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Beirne+J.J.%22&sort=score" rel="nofollow">Beirne J.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Adamczyk+B.J.%22&sort=score" rel="nofollow">Adamczyk B.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Heck+G.R.%22&sort=score" rel="nofollow">Heck G.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Cline+K.%22&sort=score" rel="nofollow">Cline K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Fernandez+D.E.%22&sort=score" rel="nofollow">Fernandez D.E.</a><br><a href="http://dx.doi.org/10.1104/pp.110.166546">Plant Physiol. 155:354-369(2011)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/21051552">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/21051552">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/21051552">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.</div></div></div></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="F4IQV7#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/21051552" typeof="ScholarlyArticle"><strong property="name">"Plastids contain a second sec translocase system with essential functions."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Skalitzky+C.A.%22&sort=score" rel="nofollow">Skalitzky C.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Martin+J.R.%22&sort=score" rel="nofollow">Martin J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Harwood+J.H.%22&sort=score" rel="nofollow">Harwood J.H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Beirne+J.J.%22&sort=score" rel="nofollow">Beirne J.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Adamczyk+B.J.%22&sort=score" rel="nofollow">Adamczyk B.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Heck+G.R.%22&sort=score" rel="nofollow">Heck G.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Cline+K.%22&sort=score" rel="nofollow">Cline K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Fernandez+D.E.%22&sort=score" rel="nofollow">Fernandez D.E.</a><br><a href="http://dx.doi.org/10.1104/pp.110.166546">Plant Physiol. 155:354-369(2011)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/21051552">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/21051552">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/21051552">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.</div></div></div></li></ul></span></span></li><li><a href="https://www.uniprot.org/locations/SL-0014">amyloplast membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding the amyloplast. Also used when it is not clear in which amyloplast membrane a protein is found." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="F4IQV7#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/21051552" typeof="ScholarlyArticle"><strong property="name">"Plastids contain a second sec translocase system with essential functions."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Skalitzky+C.A.%22&sort=score" rel="nofollow">Skalitzky C.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Martin+J.R.%22&sort=score" rel="nofollow">Martin J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Harwood+J.H.%22&sort=score" rel="nofollow">Harwood J.H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Beirne+J.J.%22&sort=score" rel="nofollow">Beirne J.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Adamczyk+B.J.%22&sort=score" rel="nofollow">Adamczyk B.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Heck+G.R.%22&sort=score" rel="nofollow">Heck G.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Cline+K.%22&sort=score" rel="nofollow">Cline K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Fernandez+D.E.%22&sort=score" rel="nofollow">Fernandez D.E.</a><br><a href="http://dx.doi.org/10.1104/pp.110.166546">Plant Physiol. 155:354-369(2011)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/21051552">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/21051552">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/21051552">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.</div></div></div></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="F4IQV7#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/21051552" typeof="ScholarlyArticle"><strong property="name">"Plastids contain a second sec translocase system with essential functions."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Skalitzky+C.A.%22&sort=score" rel="nofollow">Skalitzky C.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Martin+J.R.%22&sort=score" rel="nofollow">Martin J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Harwood+J.H.%22&sort=score" rel="nofollow">Harwood J.H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Beirne+J.J.%22&sort=score" rel="nofollow">Beirne J.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Adamczyk+B.J.%22&sort=score" rel="nofollow">Adamczyk B.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Heck+G.R.%22&sort=score" rel="nofollow">Heck G.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Cline+K.%22&sort=score" rel="nofollow">Cline K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Fernandez+D.E.%22&sort=score" rel="nofollow">Fernandez D.E.</a><br><a href="http://dx.doi.org/10.1104/pp.110.166546">Plant Physiol. 155:354-369(2011)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/21051552">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/21051552">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/21051552">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.</div></div></div></li></ul></span></span></li><li><a href="https://www.uniprot.org/locations/SL-0058">chloroplast thylakoid membrane </a><a class="icon icon-generic tooltipped" data-tippy="The thylakoid membranes of a chloroplast is an internal system of interconnected membranes, that carry out the light reactions of photosynthesis. They are arranged into stacked and unstacked regions called grana and stroma thylakoids, respectively, that are differentially enriched in photosystem I and II complexes. Although extensive, the thylakoid network in an individual chloroplast is thought to comprise a single lumenal compartment." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="F4IQV7#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/21051552" typeof="ScholarlyArticle"><strong property="name">"Plastids contain a second sec translocase system with essential functions."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Skalitzky+C.A.%22&sort=score" rel="nofollow">Skalitzky C.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Martin+J.R.%22&sort=score" rel="nofollow">Martin J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Harwood+J.H.%22&sort=score" rel="nofollow">Harwood J.H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Beirne+J.J.%22&sort=score" rel="nofollow">Beirne J.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Adamczyk+B.J.%22&sort=score" rel="nofollow">Adamczyk B.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Heck+G.R.%22&sort=score" rel="nofollow">Heck G.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Cline+K.%22&sort=score" rel="nofollow">Cline K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Fernandez+D.E.%22&sort=score" rel="nofollow">Fernandez D.E.</a><br><a href="http://dx.doi.org/10.1104/pp.110.166546">Plant Physiol. 155:354-369(2011)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/21051552">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/21051552">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/21051552">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.</div></div></div></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="F4IQV7#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/21051552" typeof="ScholarlyArticle"><strong property="name">"Plastids contain a second sec translocase system with essential functions."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Skalitzky+C.A.%22&sort=score" rel="nofollow">Skalitzky C.A.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Martin+J.R.%22&sort=score" rel="nofollow">Martin J.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Harwood+J.H.%22&sort=score" rel="nofollow">Harwood J.H.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Beirne+J.J.%22&sort=score" rel="nofollow">Beirne J.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Adamczyk+B.J.%22&sort=score" rel="nofollow">Adamczyk B.J.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Heck+G.R.%22&sort=score" rel="nofollow">Heck G.R.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Cline+K.%22&sort=score" rel="nofollow">Cline K.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Fernandez+D.E.%22&sort=score" rel="nofollow">Fernandez D.E.</a><br><a href="http://dx.doi.org/10.1104/pp.110.166546">Plant Physiol. 155:354-369(2011)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/21051552">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/21051552">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/21051552">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.</div></div></div></li></ul></span></span></li><span class="subcellular-note">Note:</span> <span property="text">Predominantly localized to envelope membranes.</span></ul></div></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[1-34]&key=Transit%20peptide">1 – 34</a></td><td class="featdescription"><span property="text">Chloroplast</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">34</td></tr></tbody></table></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[157-177]&key=Transmembrane">157 – 177</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[206-226]&key=Transmembrane">206 – 226</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[251-271]&key=Transmembrane">251 – 271</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[285-305]&key=Transmembrane">285 – 305</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[306-326]&key=Transmembrane">306 – 326</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[346-366]&key=Transmembrane">346 – 366</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[414-434]&key=Transmembrane">414 – 434</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[447-467]&key=Transmembrane">447 – 467</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[509-529]&key=Transmembrane">509 – 529</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=F4IQV7[531-551]&key=Transmembrane">531 – 551</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr></tbody></table></td><td></td><td>The sequence <a href="https://www.ebi.ac.uk/ena/data/view/AAD24832">AAD24832</a> differs from that shown. Reason: Erroneous gene model prediction.<span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span><br>The sequence <a href="https://www.ebi.ac.uk/ena/data/view/AAL32668">AAL32668</a> differs from that shown. <span property="text">Intron retention and frameshift at position 388.</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span><br>The sequence <a href="https://www.ebi.ac.uk/ena/data/view/AAM13353">AAM13353</a> differs from that shown. <span property="text">Intron retention.</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span><br>The sequence <a href="https://www.ebi.ac.uk/ena/data/view/BX820289">BX820289</a> differs from that shown. Reason: Frameshift at positions <a href="https://www.uniprot.org/blast/?about=F4IQV7%5B388,521%5D">388 and 521</a>.<span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/33090">Viridiplantae</a></td><td><a href="https://www.uniprot.org/taxonomy/35493">Streptophyta</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_180711.4">NP_180711.4</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_128710.7">NM_128710.7</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/AC007071" class="embl">AC007071</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAD24832" class="embl_cds">AAD24832.1</a> Sequence problems.<br><a href="https://www.ebi.ac.uk/ena/data/view/CP002685" class="embl">CP002685</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AEC08557" class="embl_cds">AEC08557.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AY062590" class="embl">AY062590</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAL32668" class="embl_cds">AAL32668.1</a> Sequence problems.<br><a href="https://www.ebi.ac.uk/ena/data/view/AY093354" class="embl">AY093354</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAM13353" class="embl_cds">AAM13353.1</a> Sequence problems.<br><a href="https://www.ebi.ac.uk/ena/data/view/BX820289" class="embl">BX820289</a> mRNA No translation available.<br></td><td class="addRemoveColumn mid"></td></tr><tr id="P32915" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_P32915" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/P32915">P32915</a></td><td><a href="https://www.uniprot.org/taxonomy/559292">Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)</a></td><td><div class="protein_names"><div class="short" title="Protein transport protein SEC61"><strong>Protein transport protein SEC61</strong></div><div class="long" style="display:none;"><strong>Protein transport protein SEC61</strong> (Sec61 complex subunit SEC61) (Sec61 complex subunit alpha) </div></div></td><td><div class="gene-names"><span class="shortName"><strong>SEC61</strong> YLR378C, L3502.5 </span></div></td><td class="number">480</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/P32915" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/P32915" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/559292">559292</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0097">Endoplasmic reticulum membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding the endoplasmic reticulum (ER). The endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products." data-icon="i" tabindex="0"></a>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a></li></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[1-32]&key=Topological%20domain">1 – 32</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">32</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[56-75]&key=Topological%20domain">56 – 75</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[96-119]&key=Topological%20domain">96 – 119</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">24</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[142-146]&key=Topological%20domain">142 – 146</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">5</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[168-212]&key=Topological%20domain">168 – 212</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[225-240]&key=Topological%20domain">225 – 240</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">16</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[261-290]&key=Topological%20domain">261 – 290</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">30</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[312-361]&key=Topological%20domain">312 – 361</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">50</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[382-416]&key=Topological%20domain">382 – 416</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">35</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[435-437]&key=Topological%20domain">435 – 437</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">3</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[460-480]&key=Topological%20domain">460 – 480</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">21</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[33-55]&key=Transmembrane">33 – 55</a></td><td class="featdescription"><span property="text">Helical; Name=1</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[76-95]&key=Transmembrane">76 – 95</a></td><td class="featdescription"><span property="text">Helical; Name=2</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[120-141]&key=Transmembrane">120 – 141</a></td><td class="featdescription"><span property="text">Helical; Name=3</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">22</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[147-167]&key=Transmembrane">147 – 167</a></td><td class="featdescription"><span property="text">Helical; Name=4</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[213-224]&key=Transmembrane">213 – 224</a></td><td class="featdescription"><span property="text">Helical; Name=5</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">12</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[241-260]&key=Transmembrane">241 – 260</a></td><td class="featdescription"><span property="text">Helical; Name=6</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[291-311]&key=Transmembrane">291 – 311</a></td><td class="featdescription"><span property="text">Helical; Name=7</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[362-381]&key=Transmembrane">362 – 381</a></td><td class="featdescription"><span property="text">Helical; Name=8</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[417-434]&key=Transmembrane">417 – 434</a></td><td class="featdescription"><span property="text">Helical; Name=9</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">18</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P32915[438-459]&key=Transmembrane">438 – 459</a></td><td class="featdescription"><span property="text">Helical; Name=10</span><span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></td><td></td><td class="featlength numeric">22</td></tr></tbody></table></td><td></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/4751">Fungi</a></td><td><a href="https://www.uniprot.org/taxonomy/4890">Ascomycota</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_013482.1">NP_013482.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_001182267.1">NM_001182267.1</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/X62340" class="embl">X62340</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/CAA44215" class="embl_cds">CAA44215.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/U19104" class="embl">U19104</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAB67276" class="embl_cds">AAB67276.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/U19103" class="embl">U19103</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAB67581" class="embl_cds">AAB67581.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/BK006945" class="embl">BK006945</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/DAA09680" class="embl_cds">DAA09680.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="P61620" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_P61620" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/P61620">P61620</a></td><td><a href="https://www.uniprot.org/taxonomy/10090">Mus musculus (Mouse)</a></td><td><div class="protein_names"><div class="short" title="Protein transport protein Sec61 subunit alpha isoform 1"><strong>Protein transport protein Sec61 sub...</strong></div><div class="long" style="display:none;"><strong>Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1</strong></div></div></td><td><div class="gene-names"><span class="shortName"><strong>Sec61a1</strong> Sec61a </span></div></td><td class="number">476</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/P61620" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/P61620" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/10090">10090</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0097">Endoplasmic reticulum membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding the endoplasmic reticulum (ER). The endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products." data-icon="i" tabindex="0"></a> <span class="attribution ECO250"><span class="attributionHeader ">By similarity<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-3" tabindex="0"><span style="display:none"><span class="toolTipContent"> | |
| <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> | |
| <p><a href="/manual/evidences#ECO:0000250">More...</a></p> | |
| </span></span>Manual assertion inferred from sequence similarity to<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/uniprot/P61619">UniProtKB:P61619 (S61A1_HUMAN)</a></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></li><span class="subcellular-note">Note:</span> <span property="text">Localizes exclusively in granular structures in the endoplasmic reticulum (ER).<span class="attribution ECO250"><span class="attributionHeader ">By similarity<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-3" tabindex="0">Manual assertion inferred from sequence similarity to<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/uniprot/P61619">UniProtKB:P61619 (S61A1_HUMAN)</a></li></ul></span></span></span></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[1-33]&key=Topological%20domain">1 – 33</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">33</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[54-76]&key=Topological%20domain">54 – 76</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[97-117]&key=Topological%20domain">97 – 117</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[139-144]&key=Topological%20domain">139 – 144</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">6</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[166-172]&key=Topological%20domain">166 – 172</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">7</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[194-240]&key=Topological%20domain">194 – 240</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">47</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[262-288]&key=Topological%20domain">262 – 288</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">27</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[310-354]&key=Topological%20domain">310 – 354</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[376-420]&key=Topological%20domain">376 – 420</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[442-445]&key=Topological%20domain">442 – 445</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">4</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[463-476]&key=Topological%20domain">463 – 476</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">14</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[34-53]&key=Transmembrane">34 – 53</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[77-96]&key=Transmembrane">77 – 96</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[118-138]&key=Transmembrane">118 – 138</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[145-165]&key=Transmembrane">145 – 165</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[173-193]&key=Transmembrane">173 – 193</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[241-261]&key=Transmembrane">241 – 261</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[289-309]&key=Transmembrane">289 – 309</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[355-375]&key=Transmembrane">355 – 375</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[421-441]&key=Transmembrane">421 – 441</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P61620[446-462]&key=Transmembrane">446 – 462</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">17</td></tr></tbody></table></td><td></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/33208">Metazoa</a></td><td><a href="https://www.uniprot.org/taxonomy/7711">Chordata</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_058602.1">NP_058602.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_016906.4">NM_016906.4</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/AB032902" class="embl">AB032902</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAA85159" class="embl_cds">BAA85159.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AF222743" class="embl">AF222743</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAG44252" class="embl_cds">AAG44252.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AF145253" class="embl">AF145253</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAF66695" class="embl_cds">AAF66695.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AK088473" class="embl">AK088473</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAC40375" class="embl_cds">BAC40375.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AK153055" class="embl">AK153055</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAE31681" class="embl_cds">BAE31681.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AK159349" class="embl">AK159349</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAE35011" class="embl_cds">BAE35011.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/BC003707" class="embl">BC003707</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAH03707" class="embl_cds">AAH03707.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="P38353" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_P38353" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/P38353">P38353</a></td><td><a href="https://www.uniprot.org/taxonomy/559292">Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)</a></td><td><div class="protein_names"><div class="short" title="Sec sixty-one protein homolog"><strong>Sec sixty-one protein homolog</strong></div><div class="long" style="display:none;"><strong>Sec sixty-one protein homolog</strong> (Ssh1 complex subunit SSH1) (Ssh1 complex subunit alpha) </div></div></td><td><div class="gene-names"><span class="shortName"><strong>SSH1</strong> YBR283C, YBR2020 </span></div></td><td class="number">490</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/P38353" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/P38353" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/559292">559292</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0097">Endoplasmic reticulum membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding the endoplasmic reticulum (ER). The endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products." data-icon="i" tabindex="0"></a>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a></li></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[1-32]&key=Topological%20domain">1 – 32</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">32</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[54-121]&key=Topological%20domain">54 – 121</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">68</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[143-146]&key=Topological%20domain">143 – 146</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">4</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[168-174]&key=Topological%20domain">168 – 174</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">7</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[196-242]&key=Topological%20domain">196 – 242</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">47</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[264-293]&key=Topological%20domain">264 – 293</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">30</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[315-339]&key=Topological%20domain">315 – 339</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">25</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[361]&key=Topological%20domain">361</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">1</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[383-421]&key=Topological%20domain">383 – 421</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">39</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[443-449]&key=Topological%20domain">443 – 449</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">7</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[471-490]&key=Topological%20domain">471 – 490</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[33-53]&key=Transmembrane">33 – 53</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[122-142]&key=Transmembrane">122 – 142</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[147-167]&key=Transmembrane">147 – 167</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[175-195]&key=Transmembrane">175 – 195</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[243-263]&key=Transmembrane">243 – 263</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[294-314]&key=Transmembrane">294 – 314</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[340-360]&key=Transmembrane">340 – 360</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[362-382]&key=Transmembrane">362 – 382</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[422-442]&key=Transmembrane">422 – 442</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38353[450-470]&key=Transmembrane">450 – 470</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr></tbody></table></td><td></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/4751">Fungi</a></td><td><a href="https://www.uniprot.org/taxonomy/4890">Ascomycota</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_009842.1">NP_009842.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_001178631.1">NM_001178631.1</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/U05336" class="embl">U05336</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAB40986" class="embl_cds">AAB40986.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/X76053" class="embl">X76053</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/CAA53646" class="embl_cds">CAA53646.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/Z36152" class="embl">Z36152</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/CAA85247" class="embl_cds">CAA85247.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AY692997" class="embl">AY692997</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAT93016" class="embl_cds">AAT93016.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/S77888" class="embl">S77888</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAB21097" class="embl_cds">AAB21097.2</a> Sequence problems.<br><a href="https://www.ebi.ac.uk/ena/data/view/BK006936" class="embl">BK006936</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/DAA07398" class="embl_cds">DAA07398.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="Q8STG9" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_Q8STG9" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/Q8STG9">Q8STG9</a></td><td><a href="https://www.uniprot.org/taxonomy/7227">Drosophila melanogaster (Fruit fly)</a></td><td><div class="protein_names"><div class="short" title="DSec61alpha">DSec61alpha</div><div class="long" style="display:none;">DSec61alpha (LD29847p) (Sec61 alpha subunit, isoform A) (Sec61 alpha subunit, isoform B) </div></div></td><td><div class="gene-names"><span class="shortName"><strong>Sec61alpha</strong> 0455, anon-WO0118547.195, anon-WO0118547.277, BcDNA:LD29847, BEST:LD29847 </span><span class="longName" style="display:none"><strong>Sec61alpha</strong> 0455, anon-WO0118547.195, anon-WO0118547.277, BcDNA:LD29847, BEST:LD29847, Dmel\CG9539, dSEC61A, DSec61alpha, dSec61alpha, E(br)165, endd2, l(2)k04917, LD29847, Sec61, sec61, SEC61-alpha, Sec61-alpha, Sec61a, SEC61ALPHA, sec61alpha, CG9539, Dmel_CG9539 </span><span class="expander" style="float:none"><div class="long icon_collapse" title="Collapse this column into smaller text" style="display:none"></div><div class="short icon_expand" title="Expand this column into longer text"></div></span></div></td><td class="number">476</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/Q8STG9" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/Q8STG9" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/7227">7227</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0162">Membrane </a><a class="icon icon-generic tooltipped" data-tippy="A membrane is a lipid bilayer which surrounds enclosed spaces and compartments. This selectively permeable structure is essential for effective separation of a cell or organelle from its surroundings. Membranes are composed of various types of molecules such as phospholipids, integral membrane proteins, peripheral proteins, glycoproteins, glycolipids, etc. The relative amounts of these components as well as the types of lipids are non-randomly distributed from membrane to membrane as well as between the two leaflets of a membrane." data-icon="i" tabindex="0"></a> <span class="attribution ECO256"><span class="attributionHeader ">UniRule annotation<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0"><span style="display:none"><span class="toolTipContent"> | |
| <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> | |
| <p><a href="/manual/evidences#ECO:0000256">More...</a></p> | |
| </span></span>Automatic assertion according to rules<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/unirule/RU003484">RuleBase:RU003484</a></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO256"><span class="attributionHeader ">UniRule annotation<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to rules<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/unirule/RU003484">RuleBase:RU003484</a></li></ul></span></span></li></ul></div></td><td></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[32-54]&key=Transmembrane">32 – 54</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[74-97]&key=Transmembrane">74 – 97</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">24</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[118-137]&key=Transmembrane">118 – 137</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[143-165]&key=Transmembrane">143 – 165</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[242-263]&key=Transmembrane">242 – 263</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">22</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[283-304]&key=Transmembrane">283 – 304</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">22</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[361-380]&key=Transmembrane">361 – 380</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[413-431]&key=Transmembrane">413 – 431</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">19</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8STG9[437-458]&key=Transmembrane">437 – 458</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO256"><span class="attributionHeader ">Sequence analysis<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-4" tabindex="0">Automatic assertion according to sequence analysis<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/help/sam">SAM:Phobius</a> (<a href="http://mobidb.bio.unipd.it/entries/Q8STG9">MobiDB:Q8STG9</a>)</li></ul></span></span></td><td></td><td class="featlength numeric">22</td></tr></tbody></table></td><td></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/33208">Metazoa</a></td><td><a href="https://www.uniprot.org/taxonomy/6656">Arthropoda</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_001285674.1">NP_001285674.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_001298745.1">NM_001298745.1</a><br><a href="https://www.ncbi.nlm.nih.gov/protein/NP_609034.1">NP_609034.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_135190.5">NM_135190.5</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/AE014134" class="embl">AE014134</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAF52389" class="embl_cds">AAF52389.2</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AY069569" class="embl">AY069569</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAL39714" class="embl_cds">AAL39714.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AE014134" class="embl">AE014134</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AHN54189" class="embl_cds">AHN54189.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AB062670" class="embl">AB062670</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/BAB78518" class="embl_cds">BAB78518.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="Q38885" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_Q38885" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/Q38885">Q38885</a></td><td><a href="https://www.uniprot.org/taxonomy/3702">Arabidopsis thaliana (Mouse-ear cress)</a></td><td><div class="protein_names"><div class="short" title="Preprotein translocase subunit SCY1, chloroplastic"><strong>Preprotein translocase subunit SCY1...</strong></div><div class="long" style="display:none;"><strong>Preprotein translocase subunit SCY1, chloroplastic</strong> (CpSecY) </div></div></td><td><div class="gene-names"><span class="shortName"><strong>SCY1</strong> SECY, At2g18710, MSF3.9 </span></div></td><td class="number">551</td><td><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/Q38885" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR026593">IPR026593</a> SecY<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/protein/Q38885" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/3702">3702</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0058">chloroplast thylakoid membrane </a><a class="icon icon-generic tooltipped" data-tippy="The thylakoid membranes of a chloroplast is an internal system of interconnected membranes, that carry out the light reactions of photosynthesis. They are arranged into stacked and unstacked regions called grana and stroma thylakoids, respectively, that are differentially enriched in photosystem I and II complexes. Although extensive, the thylakoid network in an individual chloroplast is thought to comprise a single lumenal compartment." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">2 Publications<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="Q38885#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/10207046" typeof="ScholarlyArticle"><strong property="name">"Chloroplast SecY is complexed to SecE and involved in the translocation of the 33-kDa but not the 23-kDa subunit of the oxygen-evolving complex."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Schuenemann+D.%22&sort=score" rel="nofollow">Schuenemann D.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Amin+P.%22&sort=score" rel="nofollow">Amin P.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hartmann+E.%22&sort=score" rel="nofollow">Hartmann E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hoffman+N.E.%22&sort=score" rel="nofollow">Hoffman N.E.</a><br><a href="http://dx.doi.org/10.1074/jbc.274.17.12177">J. Biol. Chem. 274:12177-12182(1999)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/10207046">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/10207046">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/10207046">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> SUBCELLULAR LOCATION, INTERACTION WITH SECE1.</div></div></div></li><li><div class="Q38885#ref6 referenceAttribution"><div class="reference_header">Ref.6</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/12217076" typeof="ScholarlyArticle"><strong property="name">"The thylakoid membrane protein ALB3 associates with the cpSecY-translocase in Arabidopsis thaliana."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Klostermann+E.%22&sort=score" rel="nofollow">Klostermann E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Droste+Gen+Helling+I.%22&sort=score" rel="nofollow">Droste Gen Helling I.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Carde+J.P.%22&sort=score" rel="nofollow">Carde J.P.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Schunemann+D.%22&sort=score" rel="nofollow">Schunemann D.</a><br><a href="http://dx.doi.org/10.1042/bj20021291">Biochem. J. 368:777-781(2002)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/12217076">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/12217076">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/12217076">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> SUBCELLULAR LOCATION, INTERACTION WITH ALB3.</div></div></div></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">2 Publications<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="Q38885#ref5 referenceAttribution"><div class="reference_header">Ref.5</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/10207046" typeof="ScholarlyArticle"><strong property="name">"Chloroplast SecY is complexed to SecE and involved in the translocation of the 33-kDa but not the 23-kDa subunit of the oxygen-evolving complex."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Schuenemann+D.%22&sort=score" rel="nofollow">Schuenemann D.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Amin+P.%22&sort=score" rel="nofollow">Amin P.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hartmann+E.%22&sort=score" rel="nofollow">Hartmann E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Hoffman+N.E.%22&sort=score" rel="nofollow">Hoffman N.E.</a><br><a href="http://dx.doi.org/10.1074/jbc.274.17.12177">J. Biol. Chem. 274:12177-12182(1999)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/10207046">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/10207046">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/10207046">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> SUBCELLULAR LOCATION, INTERACTION WITH SECE1.</div></div></div></li><li><div class="Q38885#ref6 referenceAttribution"><div class="reference_header">Ref.6</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/12217076" typeof="ScholarlyArticle"><strong property="name">"The thylakoid membrane protein ALB3 associates with the cpSecY-translocase in Arabidopsis thaliana."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Klostermann+E.%22&sort=score" rel="nofollow">Klostermann E.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Droste+Gen+Helling+I.%22&sort=score" rel="nofollow">Droste Gen Helling I.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Carde+J.P.%22&sort=score" rel="nofollow">Carde J.P.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Schunemann+D.%22&sort=score" rel="nofollow">Schunemann D.</a><br><a href="http://dx.doi.org/10.1042/bj20021291">Biochem. J. 368:777-781(2002)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/12217076">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/12217076">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/12217076">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> SUBCELLULAR LOCATION, INTERACTION WITH ALB3.</div></div></div></li></ul></span></span></li></ul></div></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[1-67]&key=Transit%20peptide">1 – 67</a></td><td class="featdescription"><span property="text">Chloroplast</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">67</td></tr></tbody></table></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[142-162]&key=Transmembrane">142 – 162</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[192-212]&key=Transmembrane">192 – 212</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[241-261]&key=Transmembrane">241 – 261</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[268-288]&key=Transmembrane">268 – 288</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[295-315]&key=Transmembrane">295 – 315</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[328-348]&key=Transmembrane">328 – 348</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[382-402]&key=Transmembrane">382 – 402</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[415-435]&key=Transmembrane">415 – 435</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[482-502]&key=Transmembrane">482 – 502</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q38885[503-523]&key=Transmembrane">503 – 523</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr></tbody></table></td><td></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/33090">Viridiplantae</a></td><td><a href="https://www.uniprot.org/taxonomy/35493">Streptophyta</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_179461.1">NP_179461.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_127427.3">NM_127427.3</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/U37247" class="embl">U37247</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAB60305" class="embl_cds">AAB60305.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AC005724" class="embl">AC005724</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAD08940" class="embl_cds">AAD08940.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/CP002685" class="embl">CP002685</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AEC06796" class="embl_cds">AEC06796.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AF424550" class="embl">AF424550</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAL11544" class="embl_cds">AAL11544.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AY058103" class="embl">AY058103</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAL24211" class="embl_cds">AAL24211.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/AY065093" class="embl">AY065093</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAL38269" class="embl_cds">AAL38269.1</a><br><a href="https://www.ebi.ac.uk/ena/data/view/BT002632" class="embl">BT002632</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAO11548" class="embl_cds">AAO11548.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="Q8U019" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_Q8U019" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/Q8U019">Q8U019</a></td><td><a href="https://www.uniprot.org/taxonomy/186497">Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)</a></td><td><div class="protein_names"><div class="short" title="Protein translocase subunit SecY"><strong>Protein translocase subunit SecY</strong></div><div class="long" style="display:none;"><strong>Protein translocase subunit SecY</strong> (Protein transport protein SEC61 subunit alpha homolog) </div></div></td><td><div class="gene-names"><span class="shortName"><strong>secY</strong> PF1801 </span></div></td><td class="number">468</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/Q8U019" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR026593">IPR026593</a> SecY<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/Q8U019" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/186497">186497</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0039">Cell membrane </a><a class="icon icon-generic tooltipped" data-tippy="The cell membrane is the selectively permeable membrane which separates the cytoplasm from its surroundings. Known as the cell inner membrane in prokaryotes with 2 membranes." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="Q8U019#ref2 referenceAttribution"><div class="reference_header">Ref.2</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/20855604" typeof="ScholarlyArticle"><strong property="name">"Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Egea+P.F.%22&sort=score" rel="nofollow">Egea P.F.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Stroud+R.M.%22&sort=score" rel="nofollow">Stroud R.M.</a><br><a href="http://dx.doi.org/10.1073/pnas.1012556107">Proc. Natl. Acad. Sci. U.S.A. 107:17182-17187(2010)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/20855604">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/20855604">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/20855604">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF THE SECYE COMPLEX WITH AN OPEN LATERAL GATE, SUBUNIT, SUBCELLULAR LOCATION, MUTAGENESIS OF 454-GLN--ALA-468; 459-PHE--ALA-461 AND 463-ARG-LYS-464.</div></div></div></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO269"><span class="attributionHeader ">1 Publication<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-2" tabindex="0">Manual assertion based on experiment in<sup>i</sup></span></p><ul><li><div class="Q8U019#ref2 referenceAttribution"><div class="reference_header">Ref.2</div><div class="reference_content"><div property="citation" resource="http://purl.uniprot.org/citations/20855604" typeof="ScholarlyArticle"><strong property="name">"Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes."</strong><br><a href="https://www.uniprot.org/uniprot/?query=author:%22Egea+P.F.%22&sort=score" rel="nofollow">Egea P.F.</a>, <a href="https://www.uniprot.org/uniprot/?query=author:%22Stroud+R.M.%22&sort=score" rel="nofollow">Stroud R.M.</a><br><a href="http://dx.doi.org/10.1073/pnas.1012556107">Proc. Natl. Acad. Sci. U.S.A. 107:17182-17187(2010)</a> [<a property="sameAs" href="https://www.ncbi.nlm.nih.gov/pubmed/20855604">PubMed</a>] [<a property="sameAs" href="https://europepmc.org/abstract/MED/20855604">Europe PMC</a>] [<a href="https://www.uniprot.org/citations/20855604">Abstract</a>]</div><div class="citedFor"><span class="details"><strong>Cited for:</strong></span> X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF THE SECYE COMPLEX WITH AN OPEN LATERAL GATE, SUBUNIT, SUBCELLULAR LOCATION, MUTAGENESIS OF 454-GLN--ALA-468; 459-PHE--ALA-461 AND 463-ARG-LYS-464.</div></div></div></li></ul></span></span></li></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[1-33]&key=Topological%20domain">1 – 33</a></td><td class="featdescription"><span property="text">Cytoplasmic</span></td><td></td><td class="featlength numeric">33</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[49-57]&key=Topological%20domain">49 – 57</a></td><td class="featdescription"><span property="text">Extracellular</span></td><td></td><td class="featlength numeric">9</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[89-115]&key=Topological%20domain">89 – 115</a></td><td class="featdescription"><span property="text">Cytoplasmic</span></td><td></td><td class="featlength numeric">27</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[131-148]&key=Topological%20domain">131 – 148</a></td><td class="featdescription"><span property="text">Extracellular</span></td><td></td><td class="featlength numeric">18</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[167-176]&key=Topological%20domain">167 – 176</a></td><td class="featdescription"><span property="text">Cytoplasmic</span></td><td></td><td class="featlength numeric">10</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[197-239]&key=Topological%20domain">197 – 239</a></td><td class="featdescription"><span property="text">Extracellular</span></td><td></td><td class="featlength numeric">43</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[258-285]&key=Topological%20domain">258 – 285</a></td><td class="featdescription"><span property="text">Cytoplasmic</span></td><td></td><td class="featlength numeric">28</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[304-346]&key=Topological%20domain">304 – 346</a></td><td class="featdescription"><span property="text">Extracellular</span></td><td></td><td class="featlength numeric">43</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[364-407]&key=Topological%20domain">364 – 407</a></td><td class="featdescription"><span property="text">Cytoplasmic</span></td><td></td><td class="featlength numeric">44</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[428]&key=Topological%20domain">428</a></td><td class="featdescription"><span property="text">Extracellular</span></td><td></td><td class="featlength numeric">1</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[444-468]&key=Topological%20domain">444 – 468</a></td><td class="featdescription"><span property="text">Cytoplasmic</span></td><td></td><td class="featlength numeric">25</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[34-48]&key=Transmembrane">34 – 48</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 1</span></td><td></td><td class="featlength numeric">15</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[58-88]&key=Transmembrane">58 – 88</a></td><td class="featdescription"><span property="text">Discontinuously helical; Name=Helix 2</span></td><td></td><td class="featlength numeric">31</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[116-130]&key=Transmembrane">116 – 130</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 3</span></td><td></td><td class="featlength numeric">15</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[149-166]&key=Transmembrane">149 – 166</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 4</span></td><td></td><td class="featlength numeric">18</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[177-196]&key=Transmembrane">177 – 196</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 5</span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[240-257]&key=Transmembrane">240 – 257</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 6</span></td><td></td><td class="featlength numeric">18</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[286-303]&key=Transmembrane">286 – 303</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 7</span></td><td></td><td class="featlength numeric">18</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[347-363]&key=Transmembrane">347 – 363</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 8</span></td><td></td><td class="featlength numeric">17</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[408-427]&key=Transmembrane">408 – 427</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 9</span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[429-443]&key=Transmembrane">429 – 443</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 10</span></td><td></td><td class="featlength numeric">15</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[58-71]&key=Intramembrane">58 – 71</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 2A</span></td><td></td><td class="featlength numeric">14</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[72]&key=Intramembrane">72</a></td><td class="featdescription"></td><td></td><td class="featlength numeric">1</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=Q8U019[73-88]&key=Intramembrane">73 – 88</a></td><td class="featdescription"><span property="text">Helical; Name=Helix 2B</span></td><td></td><td class="featlength numeric">16</td></tr></tbody></table></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2157">Archaea</a></td><td></td><td><a href="https://www.uniprot.org/taxonomy/28890">Euryarchaeota</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/WP_011012942.1">WP_011012942.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NC_003413.1">NC_003413.1</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/AE009950" class="embl">AE009950</a> Genomic DNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAL81925" class="embl_cds">AAL81925.1</a><br></td><td class="addRemoveColumn mid"></td></tr><tr id="P38377" class=" entry"><td class="checkboxColumn"><input class="basket-item namespace-uniprot" id="checkbox_P38377" type="checkbox"></td><td class="entryID"><a href="https://www.uniprot.org/uniprot/P38377">P38377</a></td><td><a href="https://www.uniprot.org/taxonomy/9615">Canis lupus familiaris (Dog) (Canis familiaris)</a></td><td><div class="protein_names"><div class="short" title="Protein transport protein Sec61 subunit alpha isoform 1"><strong>Protein transport protein Sec61 sub...</strong></div><div class="long" style="display:none;"><strong>Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1</strong></div></div></td><td><div class="gene-names"><span class="shortName"><strong>SEC61A1</strong> </span></div></td><td class="number">476</td><td><a href="http://pfam.xfam.org/family/PF10559">PF10559</a> Plug_translocon, 1 hit<br><a href="http://pfam.xfam.org/family/PF00344">PF00344</a> SecY, 1 hit<br><a href="http://pfam.xfam.org/protein/P38377" onclick="window.ga('DR-lines', 'click', 'DR-Pfam-Graphical-View');">View protein in Pfam</a></td><td><a href="https://www.ebi.ac.uk/interpro/entry/IPR002208">IPR002208</a> SecY/SEC61-alpha<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR030659">IPR030659</a> SecY_CS<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR023201">IPR023201</a> SecY_dom_sf<br><a href="https://www.ebi.ac.uk/interpro/entry/IPR019561">IPR019561</a> Translocon_Sec61/SecY_plug_dom<br><a href="https://www.ebi.ac.uk/interpro/protein/P38377" onclick="window.ga('DR-lines', 'click', 'DR-InterPro');">View protein in InterPro</a></td><td><a href="https://www.uniprot.org/taxonomy/9615">9615</a></td><td><div><ul class="noNumbering subcellLocations"><li><a href="https://www.uniprot.org/locations/SL-0097">Endoplasmic reticulum membrane </a><a class="icon icon-generic tooltipped" data-tippy="The membrane surrounding the endoplasmic reticulum (ER). The endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products." data-icon="i" tabindex="0"></a> <span class="attribution ECO250"><span class="attributionHeader ">By similarity<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-3" tabindex="0">Manual assertion inferred from sequence similarity to<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/uniprot/P61619">UniProtKB:P61619 (S61A1_HUMAN)</a></li></ul></span></span>; <a href="https://www.uniprot.org/locations/SL-9909">Multi-pass membrane protein </a><a class="icon icon-generic tooltipped" data-tippy="Protein spanning the membrane more than once." data-icon="i" tabindex="0"></a> <span class="attribution ECO305"><span class="attributionHeader tooltipped" title="Manual assertion inferred by curator">Curated</span></span></li><span class="subcellular-note">Note:</span> <span property="text">Localizes exclusively in granular structures in the endoplasmic reticulum (ER).<span class="attribution ECO250"><span class="attributionHeader ">By similarity<span class="showHideEvidence caret_grey displayThisInline"></span></span><span style="display:none" class="evidenceContainer"><p class="attributionExplain"><span class="context-help tooltipped-click html tipId-3" tabindex="0">Manual assertion inferred from sequence similarity to<sup>i</sup></span></p><ul><li><a href="https://www.uniprot.org/uniprot/P61619">UniProtKB:P61619 (S61A1_HUMAN)</a></li></ul></span></span></span></ul></div></td><td></td><td></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[2-33]&key=Topological%20domain">2 – 33</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">32</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[54-76]&key=Topological%20domain">54 – 76</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">23</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[97-117]&key=Topological%20domain">97 – 117</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[139-144]&key=Topological%20domain">139 – 144</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">6</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[166-172]&key=Topological%20domain">166 – 172</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">7</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[194-240]&key=Topological%20domain">194 – 240</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">47</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[262-288]&key=Topological%20domain">262 – 288</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">27</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[310-354]&key=Topological%20domain">310 – 354</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[376-420]&key=Topological%20domain">376 – 420</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">45</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[442-445]&key=Topological%20domain">442 – 445</a></td><td class="featdescription"><span property="text">Lumenal</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">4</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[463-476]&key=Topological%20domain">463 – 476</a></td><td class="featdescription"><span property="text">Cytoplasmic</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">14</td></tr></tbody></table></td><td><table class="featureTable" style="" id="results_section"><tbody><tr><th class="pos_h">Position(s)</th><th class="description_h">Description</th><th class="featid_h">Feature identifier</th><th class="length_h">Length</th></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[34-53]&key=Transmembrane">34 – 53</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[77-96]&key=Transmembrane">77 – 96</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">20</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[118-138]&key=Transmembrane">118 – 138</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[145-165]&key=Transmembrane">145 – 165</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[173-193]&key=Transmembrane">173 – 193</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[241-261]&key=Transmembrane">241 – 261</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[289-309]&key=Transmembrane">289 – 309</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[355-375]&key=Transmembrane">355 – 375</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[421-441]&key=Transmembrane">421 – 441</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">21</td></tr><tr class="feature_row" property="hasPart" typeof="CreativeWork"><td class="numeric"><a class="position tooltipped" title="BLAST subsequence" href="https://www.uniprot.org/blast/?about=P38377[446-462]&key=Transmembrane">446 – 462</a></td><td class="featdescription"><span property="text">Helical</span><span class="attribution ECO255"><span class="attributionHeader tooltipped" title="Manual assertion according to rules">Sequence analysis</span></span></td><td></td><td class="featlength numeric">17</td></tr></tbody></table></td><td></td><td></td><td></td><td><a href="https://www.uniprot.org/taxonomy/2759">Eukaryota</a></td><td><a href="https://www.uniprot.org/taxonomy/33208">Metazoa</a></td><td><a href="https://www.uniprot.org/taxonomy/7711">Chordata</a></td><td><a href="https://www.ncbi.nlm.nih.gov/protein/NP_001003315.1">NP_001003315.1</a>, <a href="https://www.ncbi.nlm.nih.gov/nuccore/NM_001003315.1">NM_001003315.1</a><br></td><td><a href="https://www.ebi.ac.uk/ena/data/view/M96629" class="embl">M96629</a> mRNA Translation: <a href="https://www.ebi.ac.uk/ena/data/view/AAA30891" class="embl_cds">AAA30891.1</a><br></td><td class="addRemoveColumn mid"></td></tr></tbody></table></form></div><span class="status"><span title="previous page" class="prevPageButton prevPageButtonGreyed"></span><strong> 1</strong> to <strong> | |
| 10 | |
| </strong> | |
| of <strong class="queryResultCount">40,814</strong> | |
| <a class="nextPageLink" href="https://www.uniprot.org/uniprot/?query=database%3a(type%3apfam+pf00344)&offset=10&sort=score"><span title="next page" class="nextPageButton"></span></a><span class="statusShow">Show | |
| <select name="limit" class="limitdropDown"><option name="10" selected="selected">10</option><option name="25">25</option><option name="50">50</option><option name="100">100</option><option name="250">250</option></select></span></span></div></div></main><footer id="page-footer"><section><h5>Tools</h5><ul><li><a href="https://www.uniprot.org/blast">BLAST</a></li><li><a href="https://www.uniprot.org/align">Align</a></li><li><a href="https://www.uniprot.org/uploadlists">Retrieve/ID mapping</a></li><li><a href="https://www.uniprot.org/peptidesearch">Peptide search</a></li></ul></section><section><h5>Core data</h5><ul><li><a href="https://www.uniprot.org/uniprot">Protein knowledgebase (UniProtKB)</a></li><li><a href="https://www.uniprot.org/uniref">Sequence clusters (UniRef)</a></li><li><a href="https://www.uniprot.org/uniparc">Sequence archive (UniParc)</a></li><li><a href="https://www.uniprot.org/proteomes">Proteomes</a></li></ul></section><section><h5>Supporting data</h5><ul><li><a href="https://www.uniprot.org/citations">Literature citations</a></li><li><a href="https://www.uniprot.org/taxonomy">Taxonomy</a></li><li><a href="https://www.uniprot.org/keywords">Keywords</a></li><li><a href="https://www.uniprot.org/locations">Subcellular locations</a></li><li><a href="https://www.uniprot.org/database">Cross-referenced databases</a></li><li><a href="https://www.uniprot.org/diseases">Diseases</a></li></ul></section><section><h5>Information</h5><ul><li><a href="https://www.uniprot.org/help/about">About UniProt</a></li><li><a href="https://www.uniprot.org/help">Help</a></li><li><a href="https://www.uniprot.org/help/?fil=section:faq">FAQ</a></li><li><a href="https://www.uniprot.org/help/?fil=section:manual">UniProtKB manual</a></li><li><a href="https://www.uniprot.org/help/technical">Technical corner</a></li><li><a href="https://www.uniprot.org/help/?query=*&fil=section:biocuration">Expert biocuration</a></li></ul></section><section><div class="uniprotlogo"><img src="./database_(type_pfam pf00344) in UniProtKB_files/uniprot-rgb-optimized.svg"></div><span>© 2002 – | |
| <span property="copyrightYear">2019</span> | |
| <a accesskey="9" href="https://www.uniprot.org/help/about">UniProt Consortium</a> | <a href="https://www.uniprot.org/help/license">License & Disclaimer</a> | <a href="https://www.uniprot.org/help/privacy">Privacy Notice</a></span><div resource="/help/about#UniProt" id="logos" typeof="NGO" property="creator"><span hidden="hidden" property="name">UniProt Consortium</span><span resource="/help/about#EBI" typeof="Organization" class="ebi" property="member"><span class="hidden" property="name">European Bioinformatics Institute</span><a href="https://www.ebi.ac.uk/" property="url"></a></span><span resource="/help/about#PIR" typeof="Organization" class="pir" property="member"><span class="hidden" property="name">Protein Information Resource</span><a href="https://pir.georgetown.edu/" property="url"></a></span><span resource="/help/about#SIB" typeof="Organization" class="sib" property="member"><span class="hidden" property="name">SIB Swiss Institute of Bioinformatics</span><a href="https://www.sib.swiss/" property="url"></a></span></div></section></footer><div id="elixir-ribbon"><a href="https://www.elixir-europe.org/platforms/data/core-data-resources"><img height="64px" width="64px" id="elixer-cdr-logo" src="./database_(type_pfam pf00344) in UniProtKB_files/elixir-cdr.gif"><h5><span class="elixir-banner-name">UniProt is an ELIXIR core data resource</span></h5></a></div><div id="UniProt-Funding"><span> | |
| Main <a href="https://www.uniprot.org/help/about">funding</a> by: | |
| </span><a property="funder" typeof="Organization" href="https://www.nih.gov/" id="nihFundingLink" class="funder"><span property="name">National Institutes of Health</span></a><a property="funder" typeof="Organization" href="https://www.embl.org/" id="ebiFundingLink" class="funder"><img src="./database_(type_pfam pf00344) in UniProtKB_files/embl-logo.png" style="width:auto;height:45px;"><span hidden="hidden" property="name">The European Molecular Biology Laboratory</span></a><a property="funder" typeof="GovernmentOrganization" href="https://www.sbfi.admin.ch/sbfi/en/home.html" id="seriFundingLink" class="funder"><img src="./database_(type_pfam pf00344) in UniProtKB_files/seri-logo.png"><span hidden="hidden" property="name">State Secretariat for Education, Research and Innovation</span><span hidden="hidden" property="alternateName">SERI</span></a></div><script src="./database_(type_pfam pf00344) in UniProtKB_files/analytics.js" async="async"></script><script> | |
| window.ga=window.ga||function(){(ga.q=ga.q||[]).push(arguments)};ga.l=+new Date; | |
| ga('create', 'UA-6228219-1', 'auto'); | |
| ga('set', 'dimension1', ''); | |
| ga('set', 'dimension2', ''); | |
| ga('set', 'anonymizeIp', true); | |
| ga('set', 'forceSSL', true); | |
| ga('send', 'pageview'); | |
| </script><div class="privacy-panel" id="privacy-panel"><p class="privacy-panel__text">We'd like to inform you that we have updated our <a href="https://www.uniprot.org/help/privacy">Privacy Notice</a> to comply | |
| with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.</p><a id="privacy-panel-accept" class="privacy-panel__button">Do not show this banner again</a></div><script src="./database_(type_pfam pf00344) in UniProtKB_files/tippy.all.min.js" type="text/javascript"></script><script type="text/javascript"> | |
| (function(){ | |
| uniprot.isInternal = false; | |
| var _scripts = ["common-bundle.js"]; | |
| if ("ie" === directory) { | |
| _scripts.push("node-bundle.js"); | |
| } | |
| uniprot.appendFn(_scripts); | |
| })(); | |
| </script><script type="text/javascript">uniprot.appendFn(["uniprot_results-bundle.js"]);</script><div class="d3-tooltip"></div></body></html> |
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment