twitter-creds.json

{
 "consumer_key": "abcYOURCONSUMERKEY",
 "consumer_secret": "abcYOURCONSUMERSECRET",
 "access_token": "abcYOURACCESSTOKEN",
 "access_token_secret": "abcYOURACCESSTOKENSECRET"
}

twitter_sideload.py

import json
from twython import Twython
with open('twitter-creds.json') as cred_file:
    creds = json.load(cred_file)

twitter = Twython(creds['consumer_key'], creds['consumer_secret'], creds['access_token'], creds['access_token_secret'])