This script exits play mode whenever script compilation is detected during an editor update.

ExitPlayModeOnScriptCompile.cs

// Copyright Cape Guy Ltd. 2015. http://capeguy.co.uk.
// Provided under the terms of the MIT license -
// http://opensource.org/licenses/MIT. Cape Guy accepts
// no responsibility for any damages, financial or otherwise,
// incurred as a result of using this code.
 
using UnityEngine;
using UnityEditor;
 
/// <summary>
/// This script exits play mode whenever script compilation is detected during an editor update.
/// </summary>
[InitializeOnLoad] // Make static initialiser be called as soon as the scripts are initialised in the editor (rather than just in play mode).
public class ExitPlayModeOnScriptCompile {
 
  // Static initialiser called by Unity Editor whenever scripts are loaded (editor or play mode)
  static ExitPlayModeOnScriptCompile () {
    Unused (_instance);
    _instance = new ExitPlayModeOnScriptCompile ();
  }
 
  private ExitPlayModeOnScriptCompile () {
    EditorApplication.update += OnEditorUpdate;
  }
 
  ~ExitPlayModeOnScriptCompile () {
    EditorApplication.update -= OnEditorUpdate;
    // Silence the unused variable warning with an if.
    _instance = null;
  }
 
  // Called each time the editor updates.
  private static void OnEditorUpdate () {
    if (EditorApplication.isPlaying && EditorApplication.isCompiling) {
      Debug.Log ("Exiting play mode due to script compilation.");
      EditorApplication.isPlaying = false;
    }
  }
 
  // Used to silence the 'is assigned by its value is never used' warning for _instance.
  private static void Unused<T> (T unusedVariable) {}
 
  private static ExitPlayModeOnScriptCompile _instance = null;
}