Just a short list of things I had to do during my sierra upgrade to get back to ship shape.
Accept the new xcode license so you can use git etc:
sudo xcodebuild -license
Take control of /usr/local again. You may not need to do this if you have a more recent homebrew than I did. homebrew now lives in /usr/local/Homebrew:
sudo chown -R $(whoami) /usr/local
And finally update / upgrade homebrew + packages:
brew update && brew upgrade
This time it was nice and easy, brew actually detected the permissions issue and everything! major shout out to the homebrew team.
Also: you may run into some weirdness with broken packages if this is the first time you've updated after the migration to /usr/local/Homebrew. I had to reinstall node for example.
tmux 2.2 merged a patch which doesn't turn off kqueue which is broken in osx (see here for details). This isn't 100% related to sierra, but this was recent enough that I figured it was worth a mention.
brew uninstall --force tmux && brew install --HEAD tmux
see here for the nitty gritty, but basically you may have to manually update tunnelblick if you see weird issues with their auto-updates. no big deal
date changed to bsd from gnu, which means some of your options may not work
pbcopy once again broken in tmux :(
see here but basically you'll need to once again use reattach-to-user-namespace with pbcopy which .. ugh
The short of it is you'll need to
brew install reattach-to-user-namespace
and add:
set-option -g default-command "reattach-to-user-namespace -l bash"
to your .tmux.conf
You'll have to migrate to Karabiner-Elements for the time being in sierra. From the main page updates are forthcoming, but not until elements is complete. I don't really use this anymore, so I don't have much more info.
https://github.com/mateor/binaries/commits/mateo.OSX_10.12