one.js

Get(/^\/myroute/, function(request) {
  ...
});

Post(/^\/myroute/, function(request) {
  ...
});

Head(/^\/myroute/, function(request) {
  ...
});

Stream(/^\/myroute/, function(request) {
  ...
});

two.js

Route("GET", /^\/myroute/, function(request) {
  ...
});

Route("POST", /^\/myroute/, function(request) {
  ...
});

Route("HEAD", /^\/myroute/, function(request) {
  ...
});