disables de-duplication in CrashPlan, which makes upload speeds much faster. Note: @thewellington did all the hard work here, I just added some to it.

crashplanFixup.sh

#!/bin/zsh
# Purpose: disable deduplication in CrashPlan
#
# From:	Tj Luo.ma
# Mail:	luomat at gmail dot com
# Web: 	http://RhymesWithDiploma.com
# Date:	2014-03-23
#
#
# Forked from: <https://gist.github.com/thewellington/8984012>
# crashplanFixup.sh for Macintosh OS X 10.9 (and probably earlier versions)
#
# This script will prevent CrashPlan from de-duplicating data on files greater than 1k.
# Based on information from http://networkrockstar.ca/2013/09/speeding-up-crashplan-backups/
#
#
# 	v1.1 	2014-03-13 by bill@wellingtonnet.net
#	v1.2	2014-03-23 by luomat@gmail.com 
#			-	removed `sudo` requirement except where explictly needed
#			-	added support for plist in ~/Library/LaunchAgents/
#			- 	added checks to make sure plist and FILEPATH both exist 
#			-	added check to make sure we haven't already done this on $FILEPATH 

NAME="$0:t:r"

# This is the path to your my.service.xml file
FILEPATH='/Library/Application Support/CrashPlan/conf/my.service.xml'

if [ ! -f "$FILEPATH" ]
then
		echo "$NAME: No file found at $FILEPATH" 
		exit 1
fi

	# Check to see if we've already done this
fgrep -i -q '<dataDeDupAutoMaxFileSizeForWan>1</dataDeDupAutoMaxFileSizeForWan>' "$FILEPATH"

EXIT="$?"

if [ "$EXIT" = "0" ]
then
		echo "$NAME: $FILEPATH has already been updated (dataDeDupAutoMaxFileSizeForWan = 1)"
		exit 0
fi

if [ -f '/Library/LaunchDaemons/com.crashplan.engine.plist' ]
then
		PLIST='/Library/LaunchDaemons/com.crashplan.engine.plist'
		LAUNCHCTL_SUDO='sudo'
elif [ -f "$HOME/Library/LaunchAgents/com.crashplan.engine.plist" ]
then
		PLIST="$HOME/Library/LaunchAgents/com.crashplan.engine.plist"
		LAUNCHCTL_SUDO=''
else
		echo "$NAME: Could not find com.crashplan.engine.plist either at 
		'$HOME/Library/LaunchAgents/com.crashplan.engine.plist' 
		or 
		'/Library/LaunchDaemons/com.crashplan.engine.plist'"
		
		exit 1
fi 				

# Sets the <dataDeDupAutoMaxFileSizeForWan> key to 1 - to prevent all files greater than 1k from being deduplicated
sudo sed -i .bak 's/\(<dataDeDupAutoMaxFileSizeForWan>\)[0-9]*\(<\/dataDeDupAutoMaxFileSizeForWan>\)/\11\2/' "${FILEPATH}"

EXIT="$?"

if [ "$EXIT" != "0" ]
then
		echo "$NAME: 'sed' command failed (\$EXIT = $EXIT)"
		exit 1
fi


# Restart CrashPlan
RESTART='1'

${LAUNCHCTL_SUDO} launchctl stop com.crashplan.engine 2>/dev/null

${LAUNCHCTL_SUDO} launchctl unload "$PLIST" 2>/dev/null

${LAUNCHCTL_SUDO} launchctl load "$PLIST" && \
	${LAUNCHCTL_SUDO} launchctl start com.crashplan.engine && \
		RESTART=0

if [ "$RESTART" = "0" ]
then
		echo "$NAME: Successfully restarted com.crashplan.engine via launchctl"
else
		echo "$NAME: FAILED to restart com.crashplan.engine via launchctl"
		exit 1
fi

	# Launch CrashPlan Menu Bar Extra - Comment out the next line if this is undesired behavior
open -g "/Applications/CrashPlan.app/Contents/Resources/CrashPlan menu bar.app"

exit
#
#EOF

great additions... The one thing I would caution you about here is that if you have multiple backup sets, the will show up once for each backup set in the my.service.xml file. You check looks for a single instance of that and if it is there, exits. It is possible that the first set would have a value of 1 while subsequent sets have a different value. This would lead to exiting the script before changing those other sets... and you would only have turned de-duplication off on the first set.