Yet another tweet deleter, the other gists didn't work for me.

delete_tweets.py

import sys
import tweepy # pip install tweepy

# options
dry_run = True

# Twitter API credentials
# Go to https://apps.twitter.com
consumer_key = ""
consumer_secret = ""
access_key = ""
access_secret = ""

doomed_tweets = []
auth = tweepy.OAuthHandler(consumer_key, consumer_secret)
auth.set_access_token(access_key, access_secret)
api = tweepy.API(auth)

# Queue tweet ids
for tweet in tweepy.Cursor(api.user_timeline).items():
    sys.stdout.write("Queuing (%d)\r" % len(doomed_tweets))
    sys.stdout.flush()
    doomed_tweets.append(tweet.id)
print "Queued %d tweets." % len(doomed_tweets)

if dry_run:
    print "Set dry_run to False to delete the queued tweets."
    sys.exit()

# Delete queued tweet ids
destroy_count = 0
for tweet in doomed_tweets:
    sys.stdout.write("Deleting (%d)\r" % destroy_count)
    sys.stdout.flush()
    api.destroy_status(tweet)
    destroy_count += 1
print "Deleted %d tweets." % destroy_count