Picker.cs

var picker = new Picker() 
{ 
    DisplayPropertyName = nameof(PickerItem.DisplayName) 
};
Add(picker);

var set = this.CreateBindingSet<MyView, MyViewModel>();
set.Bind(picker).For(v => v.ItemsSource).To(vm => vm.PickerItems);
set.Bind(picker).For(v => v.SelectedItem).To(vm => vm.SelectedItem).TwoWay();
set.Apply();