Here are the Python podcasts I am aware of.
The exposition is oriented more towards developer gossip because that was the context in which I was asked.
I link to Castro because that's convenient for me; I hope the links are not too unwieldy for others. (If you are looking for a podcast player, I don't hesitate to recommend Castro, though!)
https://castro.fm/podcast/7ba7c9d3-6edc-4af0-abb2-5f009edacb5e
Hosted by Michael Kennedy. Interviews with developers.
The very second podcast I ever listened to was one of the early shows where Michael interviewed Guido van Rossum. I was seriously underwhelmed at the time, I'm afraid, but Michael has stepped up his game significantely since then.
https://castro.fm/podcast/fdb5ef8a-d311-443b-a367-ee7b0841f8d0
Hosted by Christopher Bailey. Interviews with developers or just discussions with guests or expositions on a topic.
Somewhat oriented towards beginners in its exposition, but not unknown to delve fairly deep into some technical detail.
https://castro.fm/podcast/0aa36e78-e963-4b42-bc63-1422b860ffb6
Hosted by Tobias Macey. Interviews with developers and other guests.
A bit of a bent towards data science (the host also has a separate podcast for that audience).
The ads are unnervingly monotonous, but Tobias manages to switch to an almost human voice in the actual conversation. You just have to endure a minute of two of mind-numbing droning advertising at the beginning. (Pro tip: set the player to start some 50 seconds in.)
https://castro.fm/podcast/6268fc54-ce36-497e-ad68-df153edb8181
Hosted by Michael Kennedy and Brian Okken. As of recently, there is often a third guest host.
Weekly updates from the Python world; new or notable packages, interesting discussions, etc.
The format in recent episodes is roughly time-boxed to 20 minutes (IIRC) for the main content, but they feel free to meander after that point. Don't miss the obligatory joke at the end.
Brian's topics are often related to pytest and testing, but not annoyingly so.
While I have your attention, I might mention a few other podcasts with some relevance to software development more generally.
-
The Changelog Master feed and the Changelog main podcast almost never touch Python (perhaps because there is already a fair bit of competing podcasts in that space) and might be more interesting if you are in Javascript or Go land (each of which have their own dedicated podcasts in the Changelog catalog); but often interesting and relevant. https://changelog.com/
-
Adam Gordon-Bell's Corecursive is a low-key podcast by a student, but sometimes reaches significant heights. He once had Brian Kernighan on. Need I say more? https://corecursive.com/
-
The Stack Overflow podcast has gone through several crews and several hiatuses and several format changes over the years. The current incarnation is by and large unrelated to Stack Overflow the site, but occasionally has interesting guests and/or interesting discussions among the regular crew. https://stackoverflow.blog/podcast
-
Jack Rhysider's Darknet Diaries is a must. The topics are usually security related, sometimes serious crime and espionage, but often, too, strictly computer security. https://darknetdiaries.com/
This is by no means exhaustive. There are several more I listen to which are somewhat more niche and/or somewhat more meh.
https://www.fullstackpython.com/best-python-podcasts.html has a few more, including a Django one and one about teaching Python.