Apache Notes, these are applicable to both 2.4 and 2.2

httpd.apache notes

Check if which vhosts are running:

# httpd -S

Check your version of apache httpd

# httpd -v

If you are running centos, RHEL5,6 or 7, Fedora, remember to put

LoadModule wsgi_module modules/mod_wsgi.so
WSGISocketPrefix /var/run/wsgi

under /etc/httpd/conf.modules/10-wsgi.conf, or wherever you specify loading the wsgi module.

Is SELINUX interfering? Don't rush to disable it!

# setenforcing 0

Will immediately put it in permissive mode. Use it to debug. It'll stay until you reboot.
Also, you will likely need to set the following

# setsebool -P httpd_can_network_connect 1
# setsebool -P httpd_can_network_connect_db 1
# setsebool -P httpd_can_network_memcache 1