example tsconfig.json

tsconfig.json

{
    "compilerOptions": {
        "module": "system",
        "noImplicitAny": true,
        "removeComments": true,
        "preserveConstEnums": true,
        "outFile": "./js/final.js",
        "sourceMap": true
    },
    "include": [
        "src/**/*"
    ],
    "exclude": [
        "node_modules",
        "**/*.spec.ts",
        "lib",
        "js"
    ]
}

Requires system.js (npm install systemjs)
compile all ts files to a single js file in /js/final.js
create source map for final.js (/js/final.js.map)
will compile all files in /src/
will exclude node_modules, **/*.spec.ts, lib and js folders