Configuration files from @jsahlen blog post http://monospace.se/posts/mac-frontend-development-environment

dev

nameserver 127.0.0.1
port 20560

net.php.php-fpm.plist

<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE plist PUBLIC "-//Apple//DTD PLIST 1.0//EN" "http://www.apple.com/DTDs/PropertyList-1.0.dtd">
<plist version="1.0">
  <dict>
    <key>Label</key>
    <string>net.php.php-fpm</string>
    <key>RunAtLoad</key>
    <true/>
    <key>KeepAlive</key>
    <false/>
    <key>ProgramArguments</key>
    <array>
      <string>/usr/local/Cellar/php/5.3.10/sbin/php-fpm</string>
    </array>
    <key>WorkingDirectory</key>
    <string>/usr/local</string>
  </dict>
</plist>

pow

server {                                                                                                    
    server_name  *.dev;

    location / { 
        proxy_set_header  Host $host;
        proxy_pass  http://127.0.0.1:20559;
    }   
}

wordpress.dev

server {                                                                                                    
    server_name  wordpress.dev; # set to your desired hostname

    root /Users/walan/Sites/wordpress; # the document root

    location / { 
        index  index.php;

        # this sends all non-existing file or directory requests to index.php
        if (!-e $request_filename) {
          rewrite ^(.+)$ /index.php?q=$1 last;
        }

    }

    # pass the PHP scripts to our php-fpm server listening on 127.0.0.1:9000
    location ~ \.php$ {
        fastcgi_pass   127.0.0.1:9000;
        fastcgi_param  SCRIPT_FILENAME  $document_root$fastcgi_script_name;
        fastcgi_param  PATH_INFO        $fastcgi_script_name;
        include        fastcgi_params;
    }   
}