TTSfromClipboard.py. A quick hacky go at making a script from reading the pasteboard. Its not great -and you cant change voices unless you hard coded it. And we'd need to do some funky stuff like NLTK to find last para or last sentence.

TTSfromClipboard.py

from pynput import keyboard
import pyperclip
import pyttsx3
converter = pyttsx3.init()
# Sets speed percent
# Can be more than 100
converter.setProperty('rate', 100)
# Set volume 0-1
converter.setProperty('volume', 1)
listenAllTime = False


def on_activate_sayall():
    data = pyperclip.paste()
    converter.say(data)
    converter.runAndWait()

def on_activate_saylast_sentence():
    data = pyperclip.paste()
    converter.say(data)
    converter.runAndWait()
    

def for_canonical(f):
    return lambda k: f(l.canonical(k))


if listenAllTime:
	last_data = None
	while True:
		# get clipboard data
		data = pyperclip.paste()
		if data != last_data:
			# Changed clipboard 
		   converter.say(data)
		   converter.runAndWait()
		   last_data = data
else:
	hotkey = keyboard.HotKey(
		keyboard.HotKey.parse('<ctrl>+<alt>+s'),
		on_activate_sayall)
	with keyboard.Listener(
			on_press=for_canonical(hotkey.press),
			on_release=for_canonical(hotkey.release)) as l:
		l.join()