SublimeREPL: Python + virtualenv

gistfile1.txt

You can use:
 - virtualenvwrapper (http://virtualenvwrapper.readthedocs.org/en/latest/) with default WORKON_HOME=~/.virtualenvs (most likely you don't have to change anything) 
  - venv.bash (https://github.com/wuub/venv)
  - manually create virtualenv in one of directories scanned by SublimeREPL "python_virtualenv_paths": ["~/.virtualenvs",  "~/.venv"]

I'll assume venv.bash as it's the thing I use + it's only a syntax-sugar on top of virtualenv w/o additional features or things to understand.

$ cd ~
$ curl https://raw.github.com/wuub/venv/master/venv.bash -o venv.bash
$ source venv.bash
$ // add "source ~/venv.bash" to .bashrc or .profile if you like
$ venv create test_venv --python python3  // or any absolute path

OPTIONAL but highly recomended:
$ pip install ipython pyzmq  // in your new virtualenv (venv.bash activates it by default)


Then run SublimeText. pick SublimeREPL: Python - virtualenv, and choose your freshly created venv. 

Enjoy.