Check if the current device is using a mouse with both CSS and JavaScript.

index.js

if (matchMedia('(pointer:fine)').matches) {
  // This browser has a mouse or other fine-control device as its primary input. 
}

style.css

.some-element {
  /* Standard, mouseless behavior */
  @media (pointer: fine) {
    /* Progressively enhance to when more fine control is available. */
    /* This can be useful for animations, or for click targets
      e.g. checkboxes can be smaller when it is easier to click on them. */
  }
}