This is a transport layer in order to make xmlrpc work with any proxy type thanks to the requests library

gistfile1.py

class RequestTransport(xmlrpclib.Transport, object):

    def __init__(self, use_datetime=0, proxies=None):
        super(RequestTransport, self).__init__(use_datetime)
        self.session = requests.Session()
        self.configure_requests(proxies=proxies)

    def configure_requests(self, proxies=None):
        self.session.headers.update({
            'Content-Type': 'text/xml',
            'User-Agent': self.user_agent,
            'Accept-Encoding': 'identity',
        })
        self.session.proxies = copy(proxies)

    def set_proxy(self, proxies):
        self.session.proxies = copy(proxies)

    def request(self, host, handler, request_body, verbose=0):
        r = self.session.post('https://%s%s' % (host, handler), data=request_body)
        if r.status_code == 200:
            self.verbose = verbose
            from StringIO import StringIO
            s = StringIO(r.content)
            return self.parse_response(s)


# Usage:
proxy = RequestTransport()
proxy.set_proxy({
  'http': 'http://localhost:8080',
  'https': 'http://localhost:8080',
})

client = xmlrpclib.ServerProxy('https://pypi.python.org/pypi', transport=proxy)
reponse = client.package_releases('Django', True)
print(response)
print(response.content)