CellStyling.xaml

<Grid>
    <Grid.Resources>
        <Style TargetType="{x:Type telerik:GridViewCell}" BasedOn="{StaticResource GridViewCellStyle}">
            <Setter Property="Background" Value="#ffcc00"/>
        </Style>
        <Style TargetType="{x:Type telerik:GridViewHeaderCell}" BasedOn="{StaticResource GridViewHeaderCellStyle}">
            <Setter Property="Background" Value="LimeGreen"/>
            <Setter Property="Foreground" Value="Cyan"/>
        </Style>
    </Grid.Resources>
    <telerik:RadGridView ItemsSource="{x:Static local:SampleData.Employees}" AutoGenerateColumns="False">
        <telerik:RadGridView.Columns>
            <telerik:GridViewDataColumn Header="Name" DataMemberBinding="{Binding FullName}" />
            <telerik:GridViewDataColumn Header="Department" DataMemberBinding="{Binding Department}" />
            <telerik:GridViewDataColumn Header="Salary" DataMemberBinding="{Binding Salary}" DataFormatString="{}{0:C0}">
                <telerik:GridViewDataColumn.CellStyle>
                    <Style TargetType="{x:Type telerik:GridViewCell}" BasedOn="{StaticResource GridViewCellStyle}">
                        <Setter Property="Background" Value="Green"/>
                        <Style.Triggers>
                            <Trigger Property="IsSelected" Value="True">
                                <Setter Property="Background" Value="Red"/>
                            </Trigger>
                        </Style.Triggers>
                    </Style>
                </telerik:GridViewDataColumn.CellStyle>
            </telerik:GridViewDataColumn>
        </telerik:RadGridView.Columns>
    </telerik:RadGridView>
</Grid>

General.xaml

<telerik:RadGridView ShowGroupPanel="False" GridLinesVisibility="Vertical"
                     ShowColumnHeaders="False" ColumnBackground="Bisque"
                     RowIndicatorVisibility="Collapsed"/>

GeneralStyle.xaml

<Grid>
    <Grid.Resources>
        <Style TargetType="{x:Type telerik:RadGridView}" BasedOn="{StaticResource RadGridViewStyle}">
            <Setter Property="ShowGroupPanel" Value="False" />
            <Setter Property="GridLinesVisibility" Value="Vertical" />
            <Setter Property="ShowColumnHeaders" Value="False" />
            <Setter Property="ColumnBackground" Value="Bisque" />
            <Setter Property="RowIndicatorVisibility" Value="Collapsed" />
        </Style>
    </Grid.Resources>
    <telerik:RadGridView />
</Grid>

RowStyle.xaml

<Grid>
    <Grid.Resources>
        <Style x:Key="MyGridRowStyle" TargetType="{x:Type telerik:GridViewRow}" BasedOn="{StaticResource GridViewRowStyle}">
            <Style.Triggers>
                <Trigger Property="IsSelected" Value="True">
                    <Setter Property="Foreground" Value="Red" />
                </Trigger>
            </Style.Triggers>
        </Style>
        <Style TargetType="{x:Type telerik:GridViewRow}" BasedOn="{StaticResource MyGridRowStyle}">
            <Setter Property="Background" Value="SeaGreen"/>
        </Style>
        <Style TargetType="{x:Type telerik:GridViewHeaderRow}" BasedOn="{StaticResource GridViewHeaderRowStyle}">
            <Setter Property="Background" Value="MidnightBlue"/>
        </Style>
    </Grid.Resources>
    <telerik:RadGridView ItemsSource="{x:Static local:SampleData.Employees}" AlternationCount="2">
        <telerik:RadGridView.AlternateRowStyle>
            <Style TargetType="{x:Type telerik:GridViewRow}" BasedOn="{StaticResource MyGridRowStyle}">
                <Setter Property="Background" Value="LightGoldenrodYellow" />
            </Style>
        </telerik:RadGridView.AlternateRowStyle>
    </telerik:RadGridView>
</Grid>