How to configure enviroment variables in linux

enviroment_variables_linux

To change the environmental variable "permanently" you'll need to consider at least these situations:

Login/Non-login shell
Interactive/Non-interactive shell
bash

Bash as login shell will load /etc/profile, ~/.bash_profile, ~/.bash_login, ~/.profile in the order
Bash as non-login interactive shell will load ~/.bashrc
Bash as non-login non-interactive shell will load the configuration specified in environment variable $BASH_ENV
$EDITOR ~/.bashrc
#add lines at the bottom of the file:  
     export LD_LIBRARY_PATH=/usr/lib/oracle/11.2/client64/lib
     export ORACLE_HOME=/usr/lib/oracle/11.2/client64
zsh

$EDITOR ~/.zshrc
#add lines at the bottom of the file:  
     export LD_LIBRARY_PATH=/usr/lib/oracle/11.2/client64/lib
     export ORACLE_HOME=/usr/lib/oracle/11.2/client64
ksh

$EDITOR ~/.profile
#add lines at the bottom of the file:  
     export LD_LIBRARY_PATH=/usr/lib/oracle/11.2/client64/lib
     export ORACLE_HOME=/usr/lib/oracle/11.2/client64
bourne

$EDITOR ~/.profile
#add lines at the bottom of the file:  
     LD_LIBRARY_PATH=/usr/lib/oracle/11.2/client64/lib     
     ORACLE_HOME=/usr/lib/oracle/11.2/client64
     export LD_LIBRARY_PATH ORACLE_HOME
csh or tcsh

$EDITOR ~/.login
#add lines at the bottom of the file:  
     setenv LD_LIBRARY_PATH /usr/lib/oracle/11.2/client64/lib
     setenv ORACLE_HOME /usr/lib/oracle/11.2/client64
If you want to make it permanent for all users, you can edit /etc/profile or /etc/environment.
In this case follow the syntax you see already present in your file.