Simple Hangman Python Game

hangman.py

import random

def welcome():
    s = "hi!"
    print(s)

def generate_word():
    f = open("hangman_words.txt", "r")
    x = []
    for i in f:
        x.append(i.strip())
    
    getrand = random.randint(0, len(x))
    return x[getrand]

def game_over():
    s = '''
         #####                          #######                      
        #     #   ##   #    # ######    #     # #    # ###### #####  
        #        #  #  ##  ## #         #     # #    # #      #    # 
        #  #### #    # # ## # #####     #     # #    # #####  #    # 
        #     # ###### #    # #         #     # #    # #      #####  
        #     # #    # #    # #         #     #  #  #  #      #   #  
         #####  #    # #    # ######    #######   ##   ###### #    # 
        '''

    print(s)

def main():
    welcome()

    word = generate_word()
    tries = 10
    entries = []
    printables = list('*'*len(word))

    print("Your word is: " + ''.join(printables))

    alive = True
    while alive:
        print("You have " + str(tries) + " guesses.")

        isguessvalid = False     
        while not isguessvalid:
            guess = input("Make a guess? >> ")

            if not guess.isalpha():
                print("Invalid input. Enter a character.")
                isguessvalid = False
            elif guess == word:
                isguessvalid = True
                alive = False
            elif not len(guess) == 1:
                print("Invalid input. Enter one character.")
                isguessvalid = False
            elif guess in entries:
                print("You already tried that. Enter a new character.")
                isguessvalid = False
            else:
                isguessvalid = True
                print("You entered: " + guess)
                entries.append(guess.lower())

        if word.find(guess.lower()) == -1:
            print("Nope, try again.")
            tries = tries - 1

            if tries == 0:
                print("Na, you dead. Press F to pay respects.")
                game_over()
                print("The word was '" + word + "'.")
                alive = False
        elif alive == False: # i.e., user figured it out during guessing
            print("Cool. You win. Bye.")
        else: 
            print("Cool.")
            
            for i in range(len(word)):
                if word[i] == guess.lower():
                    printables[i] = guess.lower()

            print("Your word is: " + ''.join(printables))

main()

hangman_words.txt

transportation
independence
possibility
association
entertainment
advertising
conversation
understanding
interaction
information
preparation
environment
development
satisfaction
performance
manufacturer
requirement
supermarket
recognition
grandmother
explanation
replacement
administration
appointment
introduction
competition
refrigerator
maintenance
communication
championship
instruction
examination
distribution
contribution
perspective
imagination
consequence
construction
negotiation
organization
description
relationship
temperature
recommendation
combination
establishment
application
improvement
responsibility
measurement