Sublime Text 2 Documentation: http://www.sublimetext.com/docs/2/.
Ctrl + C copy current line (if no selection)
Ctrl + X cut current line (if no selection)
Ctrl + ⇧ + K delete line
Ctrl + ↩ insert line after
Ctrl + ⇧ + ↩ insert line before
Ctrl + ⇧ + ↑ move line (or selection) up
Ctrl + L select line (repeat to select next lines)
Ctrl + D select word (repeat select others occurrences in context for multiple editing)
Ctrl + M jump to closing bracket for current code, repeat to jump to opening bracket
Ctrl + ⇧ + M select all contents of the current brackets (curly brackets, square brackets, parentheses)
Ctrl + KK delete from cursor to end of line
Ctrl + K + ⌫ delete from cursor to start of line
Ctrl + ] indent current line(s)
Ctrl + [ un-indent current line(s)
Ctrl + ⇧ + D duplicate line(s)
Ctrl + J join line below to the end of the current line
Ctrl + / comment/un-comment current line
Ctrl + ⇧ + / block comment current selection
Ctrl + Y redo, or repeat last keyboard shortcut command
Ctrl + ⇧ + V paste and indent correctly
Ctrl + Space select next auto-complete suggestion
Ctrl + U soft undo (somehow undoes your movements; it jumps to your last change before undoing it when you repeat this command)
Ctrl + P quick-open files by name in your project (doesn't seem to need an actual project set up, it just searches in the directories around the currently-opened file
Ctrl + R goto symbol (functions and classes) in the file. Same as Ctrl + P, then type @
Ctrl + ; goto word in current file. Same as Ctrl + P, then type #
Ctrl + G goto line in current file. Same as Ctrl + P, then type :
Ctrl + ⇧ + P command prompt
Ctrl + KB toggle side bar
Ctrl + F find
Ctrl + H replace
Ctrl + ⇧ + F find in files
Ctrl + ⇧ + t open last closed tab (just like in your browser)
Ctrl + PgDn cycle down through open tabs, cycle up with Ctrl + PgUp
Ctrl + ⇆ cycle through last tabs (repeat to go back further in history)
Alt + ⇧ + 2 split into two columns
Alt + ⇧ + 1 revert to single column
Alt + ⇧ + 5 grid (4 groups)
Ctrl + [1,2,3,4] jump to "group" (pane)
Ctrl + ⇧ + [1,2,3,4] move file to specified group
Ctrl + F2 toggle bookmark
F2 next bookmark
⇧ + F2 previous bookmark
Ctrl + ⇧ + F2 clear bookmarks
Ctrl + KU upper case
Ctrl + KL lower case