syswow64detect.py

from ctypes import windll,c_ushort,byref
import platform

def is_syswow64_process():
    if platform.architecture()[0] != "64bit":
        # 32-bit OS, no syswow64 handling
        return False

    # Ok, 64-bit OS, let's see if the process is 32-bit
    # Obtain process handle to self
    this_process = windll.kernel32.GetCurrentProcess()

    # Declare ref arguments 
    proc_type, platform_type = c_ushort(), c_ushort()

    # Query Windows for the information
    wow64_call = windll.kernel32.IsWow64Process2(this_process, byref(proc_type), byref(platform_type))

    if wow64_call == 0:
        # you'd probably want to call kernel32!GetLastError here
        raise Exception("Problem querying kernel32!IsWow64Process2")

    return proc_type.value == 0