Python List Comprehension: Consonants in a string

consonants.py

'''
Create a list of all the consonants in the string "Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams"
'''
sentence = "Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams"

result = [letter for letter in sentence if letter not in 'a,e,i,o,u, " "']

I would just propose to transforme the list in a set to have a unique count of each different consonnant :

IN [ ] :
some_string = "Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams"
voyelles = ["a", "e", "i", "o", "u", "y", " "]
consonnant = [c for c in some_string.lower() if c not in voyelles]
print(set(consonnant))

OUT[ ] : {'g', 'r', 'l', 'w', 'd', 'k', 'h', 's', 'm', 't', 'n'}

vowels_space = ['a', 'e', 'i', 'o', 'u', ' ']
sentence = 'Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams'
my_list = [letter for letter in sentence.lower() if letter not in vowels_space]