How to invert mouse wheel to NaturalScrolling in Linux for Raspberry Pi
Via the Terminal, type the following
cd /usr/share/X11/xorg.conf.d sudo nano 40-libinput.conf
Add to following line to the BOTTOM of the FIRST Section "InputClass"
Option "NaturalScrolling" "true"
Here is a visual representation
Once you're finished, write to the file and then exit.
Restart your Pi
Enjoy that natural scrolling goodness!