Full blog post can be found here: http://pnommensen.com/2014/09/07/high-performance-ghost-configuration-with-nginx/
Ghost is an open source platform for blogging founded by John O'Nolan and Hannah Wolfe. It's a node.js application and therefore works great in conjunction with nginx. This guide will will help you create a high performance nginx virtual host configuration for Ghost.
The node.js application runs on a port on your server