PHPMate for Sublime Text 2

gistfile1.py

import sublime, sublime_plugin
from subprocess import Popen, PIPE, STDOUT

class RunPhpCommand(sublime_plugin.TextCommand):
	def run(self, edit):
		content = self.view.substr(sublime.Region(0, self.view.size()))
		php = Popen(['/usr/local/bin/php'], stdout=PIPE, stdin=PIPE)
		php.stdin.write(content)
		output = php.communicate()[0]
		newtab = self.view.window().new_file()
		newtab.insert(edit, 0, output)

Create a new plugin and use this as the content of that file. add a key binding if you like:

[
{ "keys": ["ctrl+r"], "command": "run_php"}
]