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kortschak/flagstat-1.svg

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flagstat CPU profiling
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flagstat-1.svg
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flagstat-8.svg
<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<!DOCTYPE svg PUBLIC "-//W3C//DTD SVG 1.1//EN"
"http://www.w3.org/Graphics/SVG/1.1/DTD/svg11.dtd">
<!-- Generated by graphviz version 2.38.0 (20140413.2041)
-->
<!-- Title: flagstat Pages: 1 -->
<svg width="100%" height="100%" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<script type="text/ecmascript"><![CDATA[
/**
* SVGPan library 1.2.1
* ======================
*
* Given an unique existing element with id "viewport" (or when missing, the first g
* element), including the the library into any SVG adds the following capabilities:
*
* - Mouse panning
* - Mouse zooming (using the wheel)
* - Object dragging
*
* You can configure the behavior of the pan/zoom/drag with the variables
* listed in the CONFIGURATION section of this file.
*
* Known issues:
*
* - Zooming (while panning) on Safari has still some issues
*
* Releases:
*
* 1.2.1, Mon Jul 4 00:33:18 CEST 2011, Andrea Leofreddi
* - Fixed a regression with mouse wheel (now working on Firefox 5)
* - Working with viewBox attribute (#4)
* - Added "use strict;" and fixed resulting warnings (#5)
* - Added configuration variables, dragging is disabled by default (#3)
*
* 1.2, Sat Mar 20 08:42:50 GMT 2010, Zeng Xiaohui
* Fixed a bug with browser mouse handler interaction
*
* 1.1, Wed Feb 3 17:39:33 GMT 2010, Zeng Xiaohui
* Updated the zoom code to support the mouse wheel on Safari/Chrome
*
* 1.0, Andrea Leofreddi
* First release
*
* This code is licensed under the following BSD license:
*
* Copyright 2009-2010 Andrea Leofreddi <a.leofreddi@itcharm.com>. All rights reserved.
*
* Redistribution and use in source and binary forms, with or without modification, are
* permitted provided that the following conditions are met:
*
* 1. Redistributions of source code must retain the above copyright notice, this list of
* conditions and the following disclaimer.
*
* 2. Redistributions in binary form must reproduce the above copyright notice, this list
* of conditions and the following disclaimer in the documentation and/or other materials
* provided with the distribution.
*
* THIS SOFTWARE IS PROVIDED BY Andrea Leofreddi ``AS IS'' AND ANY EXPRESS OR IMPLIED
* WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND
* FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL Andrea Leofreddi OR
* CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
* CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
* SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
* ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING
* NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF
* ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
*
* The views and conclusions contained in the software and documentation are those of the
* authors and should not be interpreted as representing official policies, either expressed
* or implied, of Andrea Leofreddi.
*/
"use strict";
/// CONFIGURATION
/// ====>
var enablePan = 1; // 1 or 0: enable or disable panning (default enabled)
var enableZoom = 1; // 1 or 0: enable or disable zooming (default enabled)
var enableDrag = 0; // 1 or 0: enable or disable dragging (default disabled)
/// <====
/// END OF CONFIGURATION
var root = document.documentElement;
var state = 'none', svgRoot, stateTarget, stateOrigin, stateTf;
setupHandlers(root);
/**
* Register handlers
*/
function setupHandlers(root){
setAttributes(root, {
"onmouseup" : "handleMouseUp(evt)",
"onmousedown" : "handleMouseDown(evt)",
"onmousemove" : "handleMouseMove(evt)",
//"onmouseout" : "handleMouseUp(evt)", // Decomment this to stop the pan functionality when dragging out of the SVG element
});
if(navigator.userAgent.toLowerCase().indexOf('webkit') >= 0)
window.addEventListener('mousewheel', handleMouseWheel, false); // Chrome/Safari
else
window.addEventListener('DOMMouseScroll', handleMouseWheel, false); // Others
}
/**
* Retrieves the root element for SVG manipulation. The element is then cached into the svgRoot global variable.
*/
function getRoot(root) {
if(typeof(svgRoot) == "undefined") {
var g = null;
g = root.getElementById("viewport");
if(g == null)
g = root.getElementsByTagName('g')[0];
if(g == null)
alert('Unable to obtain SVG root element');
setCTM(g, g.getCTM());
g.removeAttribute("viewBox");
svgRoot = g;
}
return svgRoot;
}
/**
* Instance an SVGPoint object with given event coordinates.
*/
function getEventPoint(evt) {
var p = root.createSVGPoint();
p.x = evt.clientX;
p.y = evt.clientY;
return p;
}
/**
* Sets the current transform matrix of an element.
*/
function setCTM(element, matrix) {
var s = "matrix(" + matrix.a + "," + matrix.b + "," + matrix.c + "," + matrix.d + "," + matrix.e + "," + matrix.f + ")";
element.setAttribute("transform", s);
}
/**
* Dumps a matrix to a string (useful for debug).
*/
function dumpMatrix(matrix) {
var s = "[ " + matrix.a + ", " + matrix.c + ", " + matrix.e + "\n " + matrix.b + ", " + matrix.d + ", " + matrix.f + "\n 0, 0, 1 ]";
return s;
}
/**
* Sets attributes of an element.
*/
function setAttributes(element, attributes){
for (var i in attributes)
element.setAttributeNS(null, i, attributes[i]);
}
/**
* Handle mouse wheel event.
*/
function handleMouseWheel(evt) {
if(!enableZoom)
return;
if(evt.preventDefault)
evt.preventDefault();
evt.returnValue = false;
var svgDoc = evt.target.ownerDocument;
var delta;
if(evt.wheelDelta)
delta = evt.wheelDelta / 3600; // Chrome/Safari
else
delta = evt.detail / -90; // Mozilla
var z = 1 + delta; // Zoom factor: 0.9/1.1
var g = getRoot(svgDoc);
var p = getEventPoint(evt);
p = p.matrixTransform(g.getCTM().inverse());
// Compute new scale matrix in current mouse position
var k = root.createSVGMatrix().translate(p.x, p.y).scale(z).translate(-p.x, -p.y);
setCTM(g, g.getCTM().multiply(k));
if(typeof(stateTf) == "undefined")
stateTf = g.getCTM().inverse();
stateTf = stateTf.multiply(k.inverse());
}
/**
* Handle mouse move event.
*/
function handleMouseMove(evt) {
if(evt.preventDefault)
evt.preventDefault();
evt.returnValue = false;
var svgDoc = evt.target.ownerDocument;
var g = getRoot(svgDoc);
if(state == 'pan' && enablePan) {
// Pan mode
var p = getEventPoint(evt).matrixTransform(stateTf);
setCTM(g, stateTf.inverse().translate(p.x - stateOrigin.x, p.y - stateOrigin.y));
} else if(state == 'drag' && enableDrag) {
// Drag mode
var p = getEventPoint(evt).matrixTransform(g.getCTM().inverse());
setCTM(stateTarget, root.createSVGMatrix().translate(p.x - stateOrigin.x, p.y - stateOrigin.y).multiply(g.getCTM().inverse()).multiply(stateTarget.getCTM()));
stateOrigin = p;
}
}
/**
* Handle click event.
*/
function handleMouseDown(evt) {
if(evt.preventDefault)
evt.preventDefault();
evt.returnValue = false;
var svgDoc = evt.target.ownerDocument;
var g = getRoot(svgDoc);
if(
evt.target.tagName == "svg"
|| !enableDrag // Pan anyway when drag is disabled and the user clicked on an element
) {
// Pan mode
state = 'pan';
stateTf = g.getCTM().inverse();
stateOrigin = getEventPoint(evt).matrixTransform(stateTf);
} else {
// Drag mode
state = 'drag';
stateTarget = evt.target;
stateTf = g.getCTM().inverse();
stateOrigin = getEventPoint(evt).matrixTransform(stateTf);
}
}
/**
* Handle mouse button release event.
*/
function handleMouseUp(evt) {
if(evt.preventDefault)
evt.preventDefault();
evt.returnValue = false;
var svgDoc = evt.target.ownerDocument;
if(state == 'pan' || state == 'drag') {
// Quit pan mode
state = '';
}
}
]]></script><g id="viewport" transform="scale(0.5,0.5) translate(0,0)"><g id="graph0" class="graph" transform="scale(1 1) rotate(0) translate(4 2106)">
<title>flagstat</title>
<polygon fill="white" stroke="none" points="-4,4 -4,-2106 2742.5,-2106 2742.5,4 -4,4"/>
<g id="clust1" class="cluster"><title>cluster_L</title>
<polygon fill="none" stroke="black" points="8,-1790 8,-2094 654,-2094 654,-1790 8,-1790"/>
</g>
<!-- L -->
<g id="node1" class="node"><title>L</title>
<polygon fill="#f8f8f8" stroke="black" points="645.5,-2086 16.5,-2086 16.5,-1798 645.5,-1798 645.5,-2086"/>
<text text-anchor="start" x="24.5" y="-2056.4" font-family="Times,serif" font-size="32.00">File: flagstat</text>
<text text-anchor="start" x="24.5" y="-2021.4" font-family="Times,serif" font-size="32.00">Type: cpu</text>
<text text-anchor="start" x="24.5" y="-1986.4" font-family="Times,serif" font-size="32.00">Time: Feb 2, 2017 at 12:41pm (ACDT)</text>
<text text-anchor="start" x="24.5" y="-1951.4" font-family="Times,serif" font-size="32.00">Duration: 1m35.344908595s</text>
<text text-anchor="start" x="24.5" y="-1916.4" font-family="Times,serif" font-size="32.00">203.88s of 217.46s total (93.76%)</text>
<text text-anchor="start" x="24.5" y="-1881.4" font-family="Times,serif" font-size="32.00">Dropped 257 nodes (cum &lt;= 1.09s)</text>
<text text-anchor="start" x="24.5" y="-1846.4" font-family="Times,serif" font-size="32.00">Dropped 29 edges (freq &lt;= 0.22s)</text>
<text text-anchor="start" x="24.5" y="-1811.4" font-family="Times,serif" font-size="32.00">Showing top 80 nodes out of 91 (cum &gt;= 1.12s)</text>
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<text text-anchor="middle" x="707" y="-1935.6" font-family="Times,serif" font-size="8.00">0 of 208.42s(95.84%)</text>
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<!-- N2 -->
<g id="node3" class="node"><title>N2</title>
<g id="a_node3"><a xlink:title="github.com/biogo/hts/bgzf.(*block).readFrom (175.24s)">
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<text text-anchor="middle" x="707" y="-1722.8" font-family="Times,serif" font-size="9.00">0.03s(0.014%)</text>
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<g id="a_edge1"><a xlink:title="runtime.goexit ... github.com/biogo/hts/bgzf.(*block).readFrom (175.24s)">
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<text text-anchor="middle" x="730.5" y="-1768.8" font-family="Times,serif" font-size="14.00"> 175.24s</text>
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<text text-anchor="middle" x="1264" y="-1722.2" font-family="Times,serif" font-size="11.00">0.87s(0.4%)</text>
<text text-anchor="middle" x="1264" y="-1710.2" font-family="Times,serif" font-size="11.00">of 16.58s(7.62%)</text>
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<text text-anchor="middle" x="1141" y="-1768.8" font-family="Times,serif" font-size="14.00"> 16.58s</text>
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<g id="a_edge12&#45;label"><a xlink:title="runtime.goexit &#45;&gt; runtime.gcBgMarkWorker (10.75s)">
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<!-- N27 -->
<g id="node28" class="node"><title>N27</title>
<g id="a_node28"><a xlink:title="github.com/biogo/hts/bgzf.NewReader.func1 (4.84s)">
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<text text-anchor="middle" x="903" y="-1722.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="903" y="-1712.8" font-family="Times,serif" font-size="9.00">of 4.84s(2.23%)</text>
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<g id="a_edge26"><a xlink:title="runtime.goexit &#45;&gt; github.com/biogo/hts/bgzf.NewReader.func1 (4.84s)">
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<g id="a_edge26&#45;label"><a xlink:title="runtime.goexit &#45;&gt; github.com/biogo/hts/bgzf.NewReader.func1 (4.84s)">
<text text-anchor="middle" x="883" y="-1768.8" font-family="Times,serif" font-size="14.00"> 4.84s</text>
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<!-- N3 -->
<g id="node4" class="node"><title>N3</title>
<g id="a_node4"><a xlink:title="compress/gzip.(*Reader).Read (175.02s)">
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<text text-anchor="middle" x="707" y="-1637.8" font-family="Times,serif" font-size="9.00">compress/gzip.(*Reader).Read</text>
<text text-anchor="middle" x="707" y="-1627.8" font-family="Times,serif" font-size="9.00">0.03s(0.014%)</text>
<text text-anchor="middle" x="707" y="-1617.8" font-family="Times,serif" font-size="9.00">of 175.02s(80.48%)</text>
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<!-- N2&#45;&gt;N3 -->
<g id="edge2" class="edge"><title>N2&#45;&gt;N3</title>
<g id="a_edge2"><a xlink:title="github.com/biogo/hts/bgzf.(*block).readFrom ... compress/gzip.(*Reader).Read (175.02s)">
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<polygon fill="black" stroke="black" stroke-width="5" points="711.375,-1659.02 707,-1649.02 702.625,-1659.02 711.375,-1659.02"/>
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<g id="a_edge2&#45;label"><a xlink:title="github.com/biogo/hts/bgzf.(*block).readFrom ... compress/gzip.(*Reader).Read (175.02s)">
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<text text-anchor="middle" x="707" y="-1545.8" font-family="Times,serif" font-size="9.00">compress/flate.(*decompressor).Read</text>
<text text-anchor="middle" x="707" y="-1535.8" font-family="Times,serif" font-size="9.00">0.11s(0.051%)</text>
<text text-anchor="middle" x="707" y="-1525.8" font-family="Times,serif" font-size="9.00">of 167.81s(77.17%)</text>
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<polygon fill="black" stroke="black" stroke-width="4" points="710.5,-1567.19 707,-1557.19 703.5,-1567.19 710.5,-1567.19"/>
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<g id="a_edge3&#45;label"><a xlink:title="compress/gzip.(*Reader).Read &#45;&gt; compress/flate.(*decompressor).Read (167.81s)">
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<text text-anchor="middle" x="1136" y="-1535.8" font-family="Times,serif" font-size="9.00">0.05s(0.023%)</text>
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<text text-anchor="middle" x="707" y="-1300.8" font-family="Times,serif" font-size="24.00">of 160.37s(73.75%)</text>
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</g>
<!-- N4&#45;&gt;N5 -->
<g id="edge7" class="edge"><title>N4&#45;&gt;N5</title>
<g id="a_edge7"><a xlink:title="compress/flate.(*decompressor).Read &#45;&gt; compress/flate.(*decompressor).huffmanBlock (49.29s)">
<path fill="none" stroke="black" stroke-width="2" d="M640.718,-1518.99C615.265,-1508.48 588.794,-1492.34 574,-1468 554.461,-1435.85 579.176,-1405.6 612.39,-1382"/>
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</a>
</g>
<g id="a_edge7&#45;label"><a xlink:title="compress/flate.(*decompressor).Read &#45;&gt; compress/flate.(*decompressor).huffmanBlock (49.29s)">
<text text-anchor="middle" x="594" y="-1443.8" font-family="Times,serif" font-size="14.00"> 49.29s</text>
</a>
</g>
</g>
<!-- N6 -->
<g id="node7" class="node"><title>N6</title>
<g id="a_node7"><a xlink:title="compress/flate.(*decompressor).nextBlock (117.77s)">
<polygon fill="#f8f8f8" stroke="black" points="791,-1466.5 623,-1466.5 623,-1428.5 791,-1428.5 791,-1466.5"/>
<text text-anchor="middle" x="707" y="-1455.3" font-family="Times,serif" font-size="9.00">compress/flate.(*decompressor).nextBlock</text>
<text text-anchor="middle" x="707" y="-1445.3" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="707" y="-1435.3" font-family="Times,serif" font-size="9.00">of 117.77s(54.16%)</text>
</a>
</g>
</g>
<!-- N4&#45;&gt;N6 -->
<g id="edge4" class="edge"><title>N4&#45;&gt;N6</title>
<g id="a_edge4"><a xlink:title="compress/flate.(*decompressor).Read &#45;&gt; compress/flate.(*decompressor).nextBlock (117.77s)">
<path fill="none" stroke="black" stroke-width="3" d="M707,-1518.66C707,-1506.6 707,-1490.57 707,-1476.87"/>
<polygon fill="black" stroke="black" stroke-width="3" points="710.5,-1476.51 707,-1466.51 703.5,-1476.51 710.5,-1476.51"/>
</a>
</g>
<g id="a_edge4&#45;label"><a xlink:title="compress/flate.(*decompressor).Read &#45;&gt; compress/flate.(*decompressor).nextBlock (117.77s)">
<text text-anchor="middle" x="730.5" y="-1489.8" font-family="Times,serif" font-size="14.00"> 117.77s</text>
</a>
</g>
</g>
<!-- N13 -->
<g id="node14" class="node"><title>N13</title>
<g id="a_node14"><a xlink:title="runtime.memmove (10.88s)">
<polygon fill="#f8f8f8" stroke="black" points="1228.5,-1085.5 1089.5,-1085.5 1089.5,-1041.5 1228.5,-1041.5 1228.5,-1085.5"/>
<text text-anchor="middle" x="1159" y="-1068.7" font-family="Times,serif" font-size="16.00">runtime.memmove</text>
<text text-anchor="middle" x="1159" y="-1050.7" font-family="Times,serif" font-size="16.00">10.88s(5.00%)</text>
</a>
</g>
</g>
<!-- N4&#45;&gt;N13 -->
<g id="edge89" class="edge"><title>N4&#45;&gt;N13</title>
<g id="a_edge89"><a xlink:title="compress/flate.(*decompressor).Read &#45;&gt; runtime.memmove (0.63s)">
<path fill="none" stroke="black" d="M782.092,-1529.62C882.203,-1516.01 1059.36,-1478.27 1168,-1376 1198.17,-1347.6 1171.78,-1316.05 1204,-1290 1237.76,-1262.71 1257.61,-1281.35 1300,-1272 1358.21,-1259.17 1393.4,-1286.05 1430,-1239 1453.47,-1208.83 1453.32,-1183.28 1430,-1153 1375.87,-1082.71 1320.24,-1132.69 1237,-1102 1227.59,-1098.53 1217.78,-1094.32 1208.43,-1089.99"/>
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<g id="a_edge89&#45;label"><a xlink:title="compress/flate.(*decompressor).Read &#45;&gt; runtime.memmove (0.63s)">
<text text-anchor="middle" x="1221" y="-1329.3" font-family="Times,serif" font-size="14.00"> 0.63s</text>
</a>
</g>
</g>
<!-- N7 -->
<g id="node8" class="node"><title>N7</title>
<g id="a_node8"><a xlink:title="compress/flate.(*decompressor).huffSym (91.23s)">
<polygon fill="#f8f8f8" stroke="black" points="914,-1239 500,-1239 500,-1153 914,-1153 914,-1239"/>
<text text-anchor="middle" x="707" y="-1215.8" font-family="Times,serif" font-size="24.00">compress/flate.(*decompressor).huffSym</text>
<text text-anchor="middle" x="707" y="-1189.8" font-family="Times,serif" font-size="24.00">50.99s(23.45%)</text>
<text text-anchor="middle" x="707" y="-1163.8" font-family="Times,serif" font-size="24.00">of 91.23s(41.95%)</text>
</a>
</g>
</g>
<!-- N5&#45;&gt;N7 -->
<g id="edge6" class="edge"><title>N5&#45;&gt;N7</title>
<g id="a_edge6"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; compress/flate.(*decompressor).huffSym (90.26s)">
<path fill="none" stroke="black" stroke-width="3" d="M707,-1289.66C707,-1276.84 707,-1262.61 707,-1249.23"/>
<polygon fill="black" stroke="black" stroke-width="3" points="710.5,-1249.19 707,-1239.19 703.5,-1249.19 710.5,-1249.19"/>
</a>
</g>
<g id="a_edge6&#45;label"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; compress/flate.(*decompressor).huffSym (90.26s)">
<text text-anchor="middle" x="727" y="-1260.8" font-family="Times,serif" font-size="14.00"> 90.26s</text>
</a>
</g>
</g>
<!-- N8 -->
<g id="node9" class="node"><title>N8</title>
<g id="a_node9"><a xlink:title="compress/flate.(*decompressor).moreBits (48.97s)">
<polygon fill="#f8f8f8" stroke="black" points="889.5,-1102 524.5,-1102 524.5,-1025 889.5,-1025 889.5,-1102"/>
<text text-anchor="middle" x="707" y="-1081.2" font-family="Times,serif" font-size="21.00">compress/flate.(*decompressor).moreBits</text>
<text text-anchor="middle" x="707" y="-1058.2" font-family="Times,serif" font-size="21.00">29.75s(13.68%)</text>
<text text-anchor="middle" x="707" y="-1035.2" font-family="Times,serif" font-size="21.00">of 48.97s(22.52%)</text>
</a>
</g>
</g>
<!-- N5&#45;&gt;N8 -->
<g id="edge15" class="edge"><title>N5&#45;&gt;N8</title>
<g id="a_edge15"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; compress/flate.(*decompressor).moreBits (8.68s)">
<path fill="none" stroke="black" d="M515.665,-1289.9C492.631,-1277.16 471.997,-1260.58 457,-1239 435.187,-1207.61 434.939,-1184.21 457,-1153 471.956,-1131.84 492.419,-1115.71 515.244,-1103.41"/>
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<g id="a_edge15&#45;label"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; compress/flate.(*decompressor).moreBits (8.68s)">
<text text-anchor="middle" x="474" y="-1192.3" font-family="Times,serif" font-size="14.00"> 8.68s</text>
</a>
</g>
</g>
<!-- N5&#45;&gt;N13 -->
<g id="edge17" class="edge"><title>N5&#45;&gt;N13</title>
<g id="a_edge17"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; runtime.memmove (7.85s)">
<path fill="none" stroke="black" d="M931.37,-1289.98C1034.14,-1269.72 1135.1,-1247.9 1143,-1239 1177.8,-1199.8 1173,-1134.32 1166.15,-1095.69"/>
<polygon fill="black" stroke="black" points="1169.52,-1094.71 1164.19,-1085.55 1162.65,-1096.04 1169.52,-1094.71"/>
</a>
</g>
<g id="a_edge17&#45;label"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; runtime.memmove (7.85s)">
<text text-anchor="middle" x="1188" y="-1192.3" font-family="Times,serif" font-size="14.00"> 7.85s</text>
</a>
</g>
</g>
<!-- N35 -->
<g id="node36" class="node"><title>N35</title>
<g id="a_node36"><a xlink:title="compress/flate.(*dictDecoder).writeCopy (2.99s)">
<polygon fill="#f8f8f8" stroke="black" points="1134,-1218 932,-1218 932,-1174 1134,-1174 1134,-1218"/>
<text text-anchor="middle" x="1033" y="-1205.2" font-family="Times,serif" font-size="11.00">compress/flate.(*dictDecoder).writeCopy</text>
<text text-anchor="middle" x="1033" y="-1193.2" font-family="Times,serif" font-size="11.00">1.65s(0.76%)</text>
<text text-anchor="middle" x="1033" y="-1181.2" font-family="Times,serif" font-size="11.00">of 2.99s(1.37%)</text>
</a>
</g>
</g>
<!-- N5&#45;&gt;N35 -->
<g id="edge30" class="edge"><title>N5&#45;&gt;N35</title>
<g id="a_edge30"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; compress/flate.(*dictDecoder).writeCopy (2.99s)">
<path fill="none" stroke="black" d="M808.807,-1289.84C862.527,-1267.59 926.62,-1241.05 972.491,-1222.06"/>
<polygon fill="black" stroke="black" points="974.093,-1225.18 981.993,-1218.12 971.414,-1218.72 974.093,-1225.18"/>
</a>
</g>
<g id="a_edge30&#45;label"><a xlink:title="compress/flate.(*decompressor).huffmanBlock &#45;&gt; compress/flate.(*dictDecoder).writeCopy (2.99s)">
<text text-anchor="middle" x="897" y="-1260.8" font-family="Times,serif" font-size="14.00"> 2.99s</text>
</a>
</g>
</g>
<!-- N6&#45;&gt;N5 -->
<g id="edge5" class="edge"><title>N6&#45;&gt;N5</title>
<g id="a_edge5"><a xlink:title="compress/flate.(*decompressor).nextBlock &#45;&gt; compress/flate.(*decompressor).huffmanBlock (111.08s)">
<path fill="none" stroke="black" stroke-width="3" d="M707,-1428.42C707,-1417.02 707,-1401.65 707,-1386.63"/>
<polygon fill="black" stroke="black" stroke-width="3" points="710.5,-1386.33 707,-1376.33 703.5,-1386.33 710.5,-1386.33"/>
</a>
</g>
<g id="a_edge5&#45;label"><a xlink:title="compress/flate.(*decompressor).nextBlock &#45;&gt; compress/flate.(*decompressor).huffmanBlock (111.08s)">
<text text-anchor="middle" x="730.5" y="-1397.8" font-family="Times,serif" font-size="14.00"> 111.08s</text>
</a>
</g>
</g>
<!-- N22 -->
<g id="node23" class="node"><title>N22</title>
<g id="a_node23"><a xlink:title="compress/flate.(*decompressor).readHuffman (6.67s)">
<polygon fill="#f8f8f8" stroke="black" points="1159,-1353.5 959,-1353.5 959,-1312.5 1159,-1312.5 1159,-1353.5"/>
<text text-anchor="middle" x="1059" y="-1341.5" font-family="Times,serif" font-size="10.00">compress/flate.(*decompressor).readHuffman</text>
<text text-anchor="middle" x="1059" y="-1330.5" font-family="Times,serif" font-size="10.00">0.45s(0.21%)</text>
<text text-anchor="middle" x="1059" y="-1319.5" font-family="Times,serif" font-size="10.00">of 6.67s(3.07%)</text>
</a>
</g>
</g>
<!-- N6&#45;&gt;N22 -->
<g id="edge22" class="edge"><title>N6&#45;&gt;N22</title>
<g id="a_edge22"><a xlink:title="compress/flate.(*decompressor).nextBlock &#45;&gt; compress/flate.(*decompressor).readHuffman (6.67s)">
<path fill="none" stroke="black" d="M775.044,-1428.43C824.032,-1415.02 891.515,-1395.71 950,-1376 966.868,-1370.31 984.983,-1363.59 1001.51,-1357.21"/>
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</g>
<g id="a_edge22&#45;label"><a xlink:title="compress/flate.(*decompressor).nextBlock &#45;&gt; compress/flate.(*decompressor).readHuffman (6.67s)">
<text text-anchor="middle" x="908" y="-1397.8" font-family="Times,serif" font-size="14.00"> 6.67s</text>
</a>
</g>
</g>
<!-- N7&#45;&gt;N8 -->
<g id="edge8" class="edge"><title>N7&#45;&gt;N8</title>
<g id="a_edge8"><a xlink:title="compress/flate.(*decompressor).huffSym &#45;&gt; compress/flate.(*decompressor).moreBits (40.24s)">
<path fill="none" stroke="black" d="M707,-1152.99C707,-1139.93 707,-1125.44 707,-1112.02"/>
<polygon fill="black" stroke="black" points="710.5,-1112.02 707,-1102.02 703.5,-1112.02 710.5,-1112.02"/>
</a>
</g>
<g id="a_edge8&#45;label"><a xlink:title="compress/flate.(*decompressor).huffSym &#45;&gt; compress/flate.(*decompressor).moreBits (40.24s)">
<text text-anchor="middle" x="727" y="-1123.8" font-family="Times,serif" font-size="14.00"> 40.24s</text>
</a>
</g>
</g>
<!-- N10 -->
<g id="node11" class="node"><title>N10</title>
<g id="a_node11"><a xlink:title="github.com/biogo/hts/bgzf.(*decompressor).ReadByte (19.22s)">
<polygon fill="#f8f8f8" stroke="black" points="913,-973 501,-973 501,-925 913,-925 913,-973"/>
<text text-anchor="middle" x="707" y="-954.6" font-family="Times,serif" font-size="18.00">github.com/biogo/hts/bgzf.(*decompressor).ReadByte</text>
<text text-anchor="middle" x="707" y="-934.6" font-family="Times,serif" font-size="18.00">19.22s(8.84%)</text>
</a>
</g>
</g>
<!-- N8&#45;&gt;N10 -->
<g id="edge9" class="edge"><title>N8&#45;&gt;N10</title>
<g id="a_edge9"><a xlink:title="compress/flate.(*decompressor).moreBits &#45;&gt; github.com/biogo/hts/bgzf.(*decompressor).ReadByte (19.22s)">
<path fill="none" stroke="black" d="M707,-1024.73C707,-1011.36 707,-996.431 707,-983.45"/>
<polygon fill="black" stroke="black" points="710.5,-983.082 707,-973.082 703.5,-983.082 710.5,-983.082"/>
</a>
</g>
<g id="a_edge9&#45;label"><a xlink:title="compress/flate.(*decompressor).moreBits &#45;&gt; github.com/biogo/hts/bgzf.(*decompressor).ReadByte (19.22s)">
<text text-anchor="middle" x="727" y="-995.8" font-family="Times,serif" font-size="14.00"> 19.22s</text>
</a>
</g>
</g>
<!-- N9 -->
<g id="node10" class="node"><title>N9</title>
<g id="a_node10"><a xlink:title="runtime.systemstack (20.12s)">
<polygon fill="#f8f8f8" stroke="black" points="2059.5,-784 1960.5,-784 1960.5,-743 2059.5,-743 2059.5,-784"/>
<text text-anchor="middle" x="2010" y="-772" font-family="Times,serif" font-size="10.00">runtime.systemstack</text>
<text text-anchor="middle" x="2010" y="-761" font-family="Times,serif" font-size="10.00">0.78s(0.36%)</text>
<text text-anchor="middle" x="2010" y="-750" font-family="Times,serif" font-size="10.00">of 20.12s(9.25%)</text>
</a>
</g>
</g>
<!-- N17 -->
<g id="node18" class="node"><title>N17</title>
<g id="a_node18"><a xlink:title="runtime.gcDrain (8.84s)">
<polygon fill="#f8f8f8" stroke="black" points="2051.5,-692 1968.5,-692 1968.5,-651 2051.5,-651 2051.5,-692"/>
<text text-anchor="middle" x="2010" y="-680" font-family="Times,serif" font-size="10.00">runtime.gcDrain</text>
<text text-anchor="middle" x="2010" y="-669" font-family="Times,serif" font-size="10.00">0.30s(0.14%)</text>
<text text-anchor="middle" x="2010" y="-658" font-family="Times,serif" font-size="10.00">of 8.84s(4.07%)</text>
</a>
</g>
</g>
<!-- N9&#45;&gt;N17 -->
<g id="edge16" class="edge"><title>N9&#45;&gt;N17</title>
<g id="a_edge16"><a xlink:title="runtime.systemstack ... runtime.gcDrain (8.33s)">
<path fill="none" stroke="black" stroke-dasharray="1,5" d="M2010,-742.971C2010,-731.141 2010,-715.809 2010,-702.468"/>
<polygon fill="black" stroke="black" points="2013.5,-702.301 2010,-692.301 2006.5,-702.301 2013.5,-702.301"/>
</a>
</g>
<g id="a_edge16&#45;label"><a xlink:title="runtime.systemstack ... runtime.gcDrain (8.33s)">
<text text-anchor="middle" x="2027" y="-713.8" font-family="Times,serif" font-size="14.00"> 8.33s</text>
</a>
</g>
</g>
<!-- N39 -->
<g id="node40" class="node"><title>N39</title>
<g id="a_node40"><a xlink:title="runtime.writebarrierptr_prewrite1.func1 (2.63s)">
<polygon fill="#f8f8f8" stroke="black" points="2347.5,-692 2168.5,-692 2168.5,-651 2347.5,-651 2347.5,-692"/>
<text text-anchor="middle" x="2258" y="-680" font-family="Times,serif" font-size="10.00">runtime.writebarrierptr_prewrite1.func1</text>
<text text-anchor="middle" x="2258" y="-669" font-family="Times,serif" font-size="10.00">0.22s(0.1%)</text>
<text text-anchor="middle" x="2258" y="-658" font-family="Times,serif" font-size="10.00">of 2.63s(1.21%)</text>
</a>
</g>
</g>
<!-- N9&#45;&gt;N39 -->
<g id="edge34" class="edge"><title>N9&#45;&gt;N39</title>
<g id="a_edge34"><a xlink:title="runtime.systemstack &#45;&gt; runtime.writebarrierptr_prewrite1.func1 (2.63s)">
<path fill="none" stroke="black" d="M2059.59,-744.503C2098.41,-730.417 2152.66,-710.728 2194.63,-695.498"/>
<polygon fill="black" stroke="black" points="2195.99,-698.727 2204.2,-692.025 2193.6,-692.147 2195.99,-698.727"/>
</a>
</g>
<g id="a_edge34&#45;label"><a xlink:title="runtime.systemstack &#45;&gt; runtime.writebarrierptr_prewrite1.func1 (2.63s)">
<text text-anchor="middle" x="2165" y="-713.8" font-family="Times,serif" font-size="14.00"> 2.63s</text>
</a>
</g>
</g>
<!-- N50 -->
<g id="node51" class="node"><title>N50</title>
<g id="a_node51"><a xlink:title="runtime.gcDrainN (1.64s)">
<polygon fill="#f8f8f8" stroke="black" points="2150.5,-690.5 2069.5,-690.5 2069.5,-652.5 2150.5,-652.5 2150.5,-690.5"/>
<text text-anchor="middle" x="2110" y="-679.3" font-family="Times,serif" font-size="9.00">runtime.gcDrainN</text>
<text text-anchor="middle" x="2110" y="-669.3" font-family="Times,serif" font-size="9.00">0.06s(0.028%)</text>
<text text-anchor="middle" x="2110" y="-659.3" font-family="Times,serif" font-size="9.00">of 1.64s(0.75%)</text>
</a>
</g>
</g>
<!-- N9&#45;&gt;N50 -->
<g id="edge50" class="edge"><title>N9&#45;&gt;N50</title>
<g id="a_edge50"><a xlink:title="runtime.systemstack ... runtime.gcDrainN (1.61s)">
<path fill="none" stroke="black" stroke-dasharray="1,5" d="M2031.7,-742.971C2046.51,-729.643 2066.26,-711.869 2082.22,-697.506"/>
<polygon fill="black" stroke="black" points="2084.62,-700.055 2089.71,-690.764 2079.93,-694.852 2084.62,-700.055"/>
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</g>
<g id="a_edge50&#45;label"><a xlink:title="runtime.systemstack ... runtime.gcDrainN (1.61s)">
<text text-anchor="middle" x="2082" y="-713.8" font-family="Times,serif" font-size="14.00"> 1.61s</text>
</a>
</g>
</g>
<!-- N60 -->
<g id="node61" class="node"><title>N60</title>
<g id="a_node61"><a xlink:title="runtime.(*mcache).nextFree.func1 (1.38s)">
<polygon fill="#f8f8f8" stroke="black" points="1922,-690.5 1784,-690.5 1784,-652.5 1922,-652.5 1922,-690.5"/>
<text text-anchor="middle" x="1853" y="-679.3" font-family="Times,serif" font-size="9.00">runtime.(*mcache).nextFree.func1</text>
<text text-anchor="middle" x="1853" y="-669.3" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="1853" y="-659.3" font-family="Times,serif" font-size="9.00">of 1.38s(0.63%)</text>
</a>
</g>
</g>
<!-- N9&#45;&gt;N60 -->
<g id="edge56" class="edge"><title>N9&#45;&gt;N60</title>
<g id="a_edge56"><a xlink:title="runtime.systemstack &#45;&gt; runtime.(*mcache).nextFree.func1 (1.38s)">
<path fill="none" stroke="black" d="M1975.93,-742.971C1951.65,-729.051 1918.91,-710.283 1893.32,-695.615"/>
<polygon fill="black" stroke="black" points="1895.01,-692.549 1884.6,-690.612 1891.53,-698.622 1895.01,-692.549"/>
</a>
</g>
<g id="a_edge56&#45;label"><a xlink:title="runtime.systemstack &#45;&gt; runtime.(*mcache).nextFree.func1 (1.38s)">
<text text-anchor="middle" x="1957" y="-713.8" font-family="Times,serif" font-size="14.00"> 1.38s</text>
</a>
</g>
</g>
<!-- N65 -->
<g id="node66" class="node"><title>N65</title>
<g id="a_node66"><a xlink:title="runtime.markroot.func1 (1.32s)">
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<text text-anchor="middle" x="2416" y="-679.3" font-family="Times,serif" font-size="9.00">runtime.markroot.func1</text>
<text text-anchor="middle" x="2416" y="-669.3" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="2416" y="-659.3" font-family="Times,serif" font-size="9.00">of 1.32s(0.61%)</text>
</a>
</g>
</g>
<!-- N9&#45;&gt;N65 -->
<g id="edge62" class="edge"><title>N9&#45;&gt;N65</title>
<g id="a_edge62"><a xlink:title="runtime.systemstack &#45;&gt; runtime.markroot.func1 (1.32s)">
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</a>
</g>
<g id="a_edge62&#45;label"><a xlink:title="runtime.systemstack &#45;&gt; runtime.markroot.func1 (1.32s)">
<text text-anchor="middle" x="2298" y="-713.8" font-family="Times,serif" font-size="14.00"> 1.32s</text>
</a>
</g>
</g>
<!-- N12 -->
<g id="node13" class="node"><title>N12</title>
<g id="a_node13"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read (15.71s)">
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<text text-anchor="middle" x="1509" y="-1639.2" font-family="Times,serif" font-size="11.00">github.com/biogo/hts/bam.(*Reader).Read</text>
<text text-anchor="middle" x="1509" y="-1627.2" font-family="Times,serif" font-size="11.00">0.93s(0.43%)</text>
<text text-anchor="middle" x="1509" y="-1615.2" font-family="Times,serif" font-size="11.00">of 15.71s(7.22%)</text>
</a>
</g>
</g>
<!-- N11&#45;&gt;N12 -->
<g id="edge11" class="edge"><title>N11&#45;&gt;N12</title>
<g id="a_edge11"><a xlink:title="main.main &#45;&gt; github.com/biogo/hts/bam.(*Reader).Read (15.71s)">
<path fill="none" stroke="black" d="M1310.08,-1706.51C1347.84,-1692.17 1401.73,-1671.72 1443.89,-1655.71"/>
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</a>
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<g id="a_edge11&#45;label"><a xlink:title="main.main &#45;&gt; github.com/biogo/hts/bam.(*Reader).Read (15.71s)">
<text text-anchor="middle" x="1422" y="-1673.8" font-family="Times,serif" font-size="14.00"> 15.71s</text>
</a>
</g>
</g>
<!-- N16 -->
<g id="node17" class="node"><title>N16</title>
<g id="a_node17"><a xlink:title="github.com/biogo/hts/bam.newBuffer (10s)">
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<text text-anchor="middle" x="1663" y="-1456" font-family="Times,serif" font-size="10.00">github.com/biogo/hts/bam.newBuffer</text>
<text text-anchor="middle" x="1663" y="-1445" font-family="Times,serif" font-size="10.00">0.68s(0.31%)</text>
<text text-anchor="middle" x="1663" y="-1434" font-family="Times,serif" font-size="10.00">of 10s(4.60%)</text>
</a>
</g>
</g>
<!-- N12&#45;&gt;N16 -->
<g id="edge13" class="edge"><title>N12&#45;&gt;N16</title>
<g id="a_edge13"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; github.com/biogo/hts/bam.newBuffer (10s)">
<path fill="none" stroke="black" d="M1542.75,-1607.84C1550.14,-1602.47 1557.65,-1596.39 1564,-1590 1598.47,-1555.31 1629.21,-1507.37 1646.98,-1477.16"/>
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<g id="a_edge13&#45;label"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; github.com/biogo/hts/bam.newBuffer (10s)">
<text text-anchor="middle" x="1631.5" y="-1534.3" font-family="Times,serif" font-size="14.00"> 10s</text>
</a>
</g>
</g>
<!-- N26 -->
<g id="node27" class="node"><title>N26</title>
<g id="a_node27"><a xlink:title="runtime.newobject (5.17s)">
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<text text-anchor="middle" x="1795" y="-1071.3" font-family="Times,serif" font-size="9.00">runtime.newobject</text>
<text text-anchor="middle" x="1795" y="-1061.3" font-family="Times,serif" font-size="9.00">0.17s(0.078%)</text>
<text text-anchor="middle" x="1795" y="-1051.3" font-family="Times,serif" font-size="9.00">of 5.17s(2.38%)</text>
</a>
</g>
</g>
<!-- N12&#45;&gt;N26 -->
<g id="edge40" class="edge"><title>N12&#45;&gt;N26</title>
<g id="a_edge40"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; runtime.newobject (2.13s)">
<path fill="none" stroke="black" d="M1511.03,-1607.72C1515.63,-1568.78 1529.68,-1484.76 1569,-1427 1576.31,-1416.27 1583.61,-1418.9 1592,-1409 1641.78,-1350.29 1637.81,-1324.39 1675,-1257 1700.57,-1210.66 1704.89,-1197.84 1733,-1153 1746.32,-1131.75 1762.64,-1108.56 1775.19,-1091.25"/>
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<g id="a_edge40&#45;label"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; runtime.newobject (2.13s)">
<text text-anchor="middle" x="1621" y="-1397.8" font-family="Times,serif" font-size="14.00"> 2.13s</text>
</a>
</g>
</g>
<!-- N38 -->
<g id="node39" class="node"><title>N38</title>
<g id="a_node39"><a xlink:title="runtime.writebarrierptr (2.63s)">
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<text text-anchor="middle" x="1964" y="-1203.8" font-family="Times,serif" font-size="9.00">runtime.writebarrierptr</text>
<text text-anchor="middle" x="1964" y="-1193.8" font-family="Times,serif" font-size="9.00">0.10s(0.046%)</text>
<text text-anchor="middle" x="1964" y="-1183.8" font-family="Times,serif" font-size="9.00">of 2.63s(1.21%)</text>
</a>
</g>
</g>
<!-- N12&#45;&gt;N38 -->
<g id="edge91" class="edge"><title>N12&#45;&gt;N38</title>
<g id="a_edge91"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; runtime.writebarrierptr (0.60s)">
<path fill="none" stroke="black" d="M1611.37,-1624.57C1681.5,-1617.52 1774.26,-1599.98 1845,-1557 1938.54,-1500.17 1972.15,-1477.94 2012,-1376 2031.41,-1326.35 2020.89,-1304.65 1997,-1257 1991.53,-1246.1 1985.15,-1234.3 1979.46,-1224.07"/>
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</g>
<g id="a_edge91&#45;label"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; runtime.writebarrierptr (0.60s)">
<text text-anchor="middle" x="2006" y="-1443.8" font-family="Times,serif" font-size="14.00"> 0.60s</text>
</a>
</g>
</g>
<!-- N64 -->
<g id="node65" class="node"><title>N64</title>
<g id="a_node65"><a xlink:title="runtime.slicebytetostring (1.35s)">
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<text text-anchor="middle" x="1784" y="-1545.8" font-family="Times,serif" font-size="9.00">runtime.slicebytetostring</text>
<text text-anchor="middle" x="1784" y="-1535.8" font-family="Times,serif" font-size="9.00">0.08s(0.037%)</text>
<text text-anchor="middle" x="1784" y="-1525.8" font-family="Times,serif" font-size="9.00">of 1.35s(0.62%)</text>
</a>
</g>
</g>
<!-- N12&#45;&gt;N64 -->
<g id="edge59" class="edge"><title>N12&#45;&gt;N64</title>
<g id="a_edge59"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; runtime.slicebytetostring (1.35s)">
<path fill="none" stroke="black" d="M1584.38,-1607.98C1603.57,-1602.37 1624.11,-1596.16 1643,-1590 1670.76,-1580.95 1701.26,-1570.04 1726.78,-1560.64"/>
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</a>
</g>
<g id="a_edge59&#45;label"><a xlink:title="github.com/biogo/hts/bam.(*Reader).Read &#45;&gt; runtime.slicebytetostring (1.35s)">
<text text-anchor="middle" x="1703" y="-1578.8" font-family="Times,serif" font-size="14.00"> 1.35s</text>
</a>
</g>
</g>
<!-- N14&#45;&gt;N9 -->
<g id="edge14" class="edge"><title>N14&#45;&gt;N9</title>
<g id="a_edge14"><a xlink:title="runtime.gcBgMarkWorker &#45;&gt; runtime.systemstack (9.45s)">
<path fill="none" stroke="black" d="M2062.85,-929.844C2057.73,-914.673 2050.29,-892.459 2044,-873 2035.35,-846.246 2025.8,-815.673 2019.03,-793.815"/>
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</a>
</g>
<g id="a_edge14&#45;label"><a xlink:title="runtime.gcBgMarkWorker &#45;&gt; runtime.systemstack (9.45s)">
<text text-anchor="middle" x="2061" y="-850.3" font-family="Times,serif" font-size="14.00"> 9.45s</text>
</a>
</g>
</g>
<!-- N75 -->
<g id="node76" class="node"><title>N75</title>
<g id="a_node76"><a xlink:title="runtime.gcMarkDone (1.25s)">
<polygon fill="#f8f8f8" stroke="black" points="2179.5,-873 2086.5,-873 2086.5,-835 2179.5,-835 2179.5,-873"/>
<text text-anchor="middle" x="2133" y="-861.8" font-family="Times,serif" font-size="9.00">runtime.gcMarkDone</text>
<text text-anchor="middle" x="2133" y="-851.8" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="2133" y="-841.8" font-family="Times,serif" font-size="9.00">of 1.25s(0.57%)</text>
</a>
</g>
</g>
<!-- N14&#45;&gt;N75 -->
<g id="edge72" class="edge"><title>N14&#45;&gt;N75</title>
<g id="a_edge72"><a xlink:title="runtime.gcBgMarkWorker &#45;&gt; runtime.gcMarkDone (1.22s)">
<path fill="none" stroke="black" d="M2081.64,-929.626C2091.08,-915.908 2104.12,-896.96 2114.7,-881.589"/>
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</a>
</g>
<g id="a_edge72&#45;label"><a xlink:title="runtime.gcBgMarkWorker &#45;&gt; runtime.gcMarkDone (1.22s)">
<text text-anchor="middle" x="2123" y="-894.8" font-family="Times,serif" font-size="14.00"> 1.22s</text>
</a>
</g>
</g>
<!-- N15 -->
<g id="node16" class="node"><title>N15</title>
<g id="a_node16"><a xlink:title="runtime.mallocgc (10.24s)">
<polygon fill="#f8f8f8" stroke="black" points="1814,-974 1704,-974 1704,-924 1814,-924 1814,-974"/>
<text text-anchor="middle" x="1759" y="-959.6" font-family="Times,serif" font-size="13.00">runtime.mallocgc</text>
<text text-anchor="middle" x="1759" y="-945.6" font-family="Times,serif" font-size="13.00">3.22s(1.48%)</text>
<text text-anchor="middle" x="1759" y="-931.6" font-family="Times,serif" font-size="13.00">of 10.24s(4.71%)</text>
</a>
</g>
</g>
<!-- N15&#45;&gt;N9 -->
<g id="edge77" class="edge"><title>N15&#45;&gt;N9</title>
<g id="a_edge77"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.systemstack (1.11s)">
<path fill="none" stroke="black" d="M1703.74,-938.423C1629.76,-923.271 1512.87,-889.739 1559,-835 1608.28,-776.53 1839.54,-766.15 1950.41,-764.583"/>
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</a>
</g>
<g id="a_edge77&#45;label"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.systemstack (1.11s)">
<text text-anchor="middle" x="1576" y="-850.3" font-family="Times,serif" font-size="14.00"> 1.11s</text>
</a>
</g>
</g>
<!-- N44 -->
<g id="node45" class="node"><title>N44</title>
<g id="a_node45"><a xlink:title="runtime.(*mcache).nextFree (1.84s)">
<polygon fill="#f8f8f8" stroke="black" points="1958,-873 1842,-873 1842,-835 1958,-835 1958,-873"/>
<text text-anchor="middle" x="1900" y="-861.8" font-family="Times,serif" font-size="9.00">runtime.(*mcache).nextFree</text>
<text text-anchor="middle" x="1900" y="-851.8" font-family="Times,serif" font-size="9.00">0.06s(0.028%)</text>
<text text-anchor="middle" x="1900" y="-841.8" font-family="Times,serif" font-size="9.00">of 1.84s(0.85%)</text>
</a>
</g>
</g>
<!-- N15&#45;&gt;N44 -->
<g id="edge44" class="edge"><title>N15&#45;&gt;N44</title>
<g id="a_edge44"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.(*mcache).nextFree (1.84s)">
<path fill="none" stroke="black" d="M1795.68,-923.808C1816.67,-909.963 1842.9,-892.66 1863.81,-878.869"/>
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</a>
</g>
<g id="a_edge44&#45;label"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.(*mcache).nextFree (1.84s)">
<text text-anchor="middle" x="1859" y="-894.8" font-family="Times,serif" font-size="14.00"> 1.84s</text>
</a>
</g>
</g>
<!-- N46 -->
<g id="node47" class="node"><title>N46</title>
<g id="a_node47"><a xlink:title="runtime.gcAssistAlloc (1.75s)">
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<text text-anchor="middle" x="1466" y="-861.8" font-family="Times,serif" font-size="9.00">runtime.gcAssistAlloc</text>
<text text-anchor="middle" x="1466" y="-851.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="1466" y="-841.8" font-family="Times,serif" font-size="9.00">of 1.75s(0.8%)</text>
</a>
</g>
</g>
<!-- N15&#45;&gt;N46 -->
<g id="edge45" class="edge"><title>N15&#45;&gt;N46</title>
<g id="a_edge45"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.gcAssistAlloc (1.75s)">
<path fill="none" stroke="black" d="M1703.94,-943.989C1638.73,-938.389 1534.82,-926.532 1502,-906 1492.7,-900.18 1485.12,-890.986 1479.36,-881.997"/>
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</a>
</g>
<g id="a_edge45&#45;label"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.gcAssistAlloc (1.75s)">
<text text-anchor="middle" x="1519" y="-894.8" font-family="Times,serif" font-size="14.00"> 1.75s</text>
</a>
</g>
</g>
<!-- N80 -->
<g id="node81" class="node"><title>N80</title>
<g id="a_node81"><a xlink:title="runtime.heapBitsSetType (1.12s)">
<polygon fill="#f8f8f8" stroke="black" points="1823.5,-872 1694.5,-872 1694.5,-836 1823.5,-836 1823.5,-872"/>
<text text-anchor="middle" x="1759" y="-857.2" font-family="Times,serif" font-size="11.00">runtime.heapBitsSetType</text>
<text text-anchor="middle" x="1759" y="-845.2" font-family="Times,serif" font-size="11.00">1.12s(0.52%)</text>
</a>
</g>
</g>
<!-- N15&#45;&gt;N80 -->
<g id="edge76" class="edge"><title>N15&#45;&gt;N80</title>
<g id="a_edge76"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.heapBitsSetType (1.12s)">
<path fill="none" stroke="black" d="M1759,-923.565C1759,-910.952 1759,-895.519 1759,-882.491"/>
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</a>
</g>
<g id="a_edge76&#45;label"><a xlink:title="runtime.mallocgc &#45;&gt; runtime.heapBitsSetType (1.12s)">
<text text-anchor="middle" x="1776" y="-894.8" font-family="Times,serif" font-size="14.00"> 1.12s</text>
</a>
</g>
</g>
<!-- N16&#45;&gt;N26 -->
<g id="edge75" class="edge"><title>N16&#45;&gt;N26</title>
<g id="a_edge75"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.newobject (1.15s)">
<path fill="none" stroke="black" d="M1670.51,-1426.69C1672.64,-1420.99 1674.94,-1414.76 1677,-1409 1718.9,-1291.92 1766.07,-1151.39 1785.68,-1092.55"/>
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</a>
</g>
<g id="a_edge75&#45;label"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.newobject (1.15s)">
<text text-anchor="middle" x="1745" y="-1260.8" font-family="Times,serif" font-size="14.00"> 1.15s</text>
</a>
</g>
</g>
<!-- N29 -->
<g id="node30" class="node"><title>N29</title>
<g id="a_node30"><a xlink:title="runtime.makeslice (4.52s)">
<polygon fill="#f8f8f8" stroke="black" points="1337.5,-1084 1246.5,-1084 1246.5,-1043 1337.5,-1043 1337.5,-1084"/>
<text text-anchor="middle" x="1292" y="-1072" font-family="Times,serif" font-size="10.00">runtime.makeslice</text>
<text text-anchor="middle" x="1292" y="-1061" font-family="Times,serif" font-size="10.00">0.32s(0.15%)</text>
<text text-anchor="middle" x="1292" y="-1050" font-family="Times,serif" font-size="10.00">of 4.52s(2.08%)</text>
</a>
</g>
</g>
<!-- N16&#45;&gt;N29 -->
<g id="edge42" class="edge"><title>N16&#45;&gt;N29</title>
<g id="a_edge42"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.makeslice (1.87s)">
<path fill="none" stroke="black" d="M1667.6,-1426.92C1679.76,-1369.61 1706.06,-1201.17 1617,-1120 1594.78,-1099.75 1375.42,-1111.81 1347,-1102 1338.76,-1099.15 1330.59,-1094.73 1323.18,-1089.9"/>
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</g>
<g id="a_edge42&#45;label"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.makeslice (1.87s)">
<text text-anchor="middle" x="1697" y="-1260.8" font-family="Times,serif" font-size="14.00"> 1.87s</text>
</a>
</g>
</g>
<!-- N30 -->
<g id="node31" class="node"><title>N30</title>
<g id="a_node31"><a xlink:title="io.ReadFull (4.38s)">
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<text text-anchor="middle" x="1557" y="-1340.8" font-family="Times,serif" font-size="9.00">io.ReadFull</text>
<text text-anchor="middle" x="1557" y="-1330.8" font-family="Times,serif" font-size="9.00">0.16s(0.074%)</text>
<text text-anchor="middle" x="1557" y="-1320.8" font-family="Times,serif" font-size="9.00">of 4.38s(2.01%)</text>
</a>
</g>
</g>
<!-- N16&#45;&gt;N30 -->
<g id="edge31" class="edge"><title>N16&#45;&gt;N30</title>
<g id="a_edge31"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; io.ReadFull (2.92s)">
<path fill="none" stroke="black" d="M1577.9,-1427.13C1570.18,-1422.35 1563.29,-1416.4 1558,-1409 1548.46,-1395.66 1548.07,-1377.29 1550.13,-1362.07"/>
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<g id="a_edge31&#45;label"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; io.ReadFull (2.92s)">
<text text-anchor="middle" x="1575" y="-1397.8" font-family="Times,serif" font-size="14.00"> 2.92s</text>
</a>
</g>
</g>
<!-- N16&#45;&gt;N38 -->
<g id="edge92" class="edge"><title>N16&#45;&gt;N38</title>
<g id="a_edge92"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.writebarrierptr (0.57s)">
<path fill="none" stroke="black" d="M1744.29,-1426.89C1774.02,-1416.16 1805.77,-1399.99 1828,-1376 1856.28,-1345.48 1841.11,-1324.07 1865,-1290 1883.52,-1263.58 1910.53,-1238.83 1931.66,-1221.52"/>
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<g id="a_edge92&#45;label"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.writebarrierptr (0.57s)">
<text text-anchor="middle" x="1882" y="-1329.3" font-family="Times,serif" font-size="14.00"> 0.57s</text>
</a>
</g>
</g>
<!-- N48 -->
<g id="node49" class="node"><title>N48</title>
<g id="a_node49"><a xlink:title="runtime.deferreturn (1.69s)">
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<text text-anchor="middle" x="1955" y="-1341.5" font-family="Times,serif" font-size="10.00">runtime.deferreturn</text>
<text text-anchor="middle" x="1955" y="-1330.5" font-family="Times,serif" font-size="10.00">0.30s(0.14%)</text>
<text text-anchor="middle" x="1955" y="-1319.5" font-family="Times,serif" font-size="10.00">of 1.69s(0.78%)</text>
</a>
</g>
</g>
<!-- N16&#45;&gt;N48 -->
<g id="edge53" class="edge"><title>N16&#45;&gt;N48</title>
<g id="a_edge53"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.deferreturn (1.47s)">
<path fill="none" stroke="black" d="M1748.16,-1428.84C1751.48,-1428.21 1754.77,-1427.59 1758,-1427 1807.16,-1417.97 1823.76,-1430.24 1869,-1409 1893.1,-1397.68 1915.6,-1377.57 1931.54,-1361.03"/>
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<g id="a_edge53&#45;label"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.deferreturn (1.47s)">
<text text-anchor="middle" x="1910" y="-1397.8" font-family="Times,serif" font-size="14.00"> 1.47s</text>
</a>
</g>
</g>
<!-- N78 -->
<g id="node79" class="node"><title>N78</title>
<g id="a_node79"><a xlink:title="runtime.deferproc (1.15s)">
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<text text-anchor="middle" x="1774" y="-1341.5" font-family="Times,serif" font-size="10.00">runtime.deferproc</text>
<text text-anchor="middle" x="1774" y="-1330.5" font-family="Times,serif" font-size="10.00">0.23s(0.11%)</text>
<text text-anchor="middle" x="1774" y="-1319.5" font-family="Times,serif" font-size="10.00">of 1.15s(0.53%)</text>
</a>
</g>
</g>
<!-- N16&#45;&gt;N78 -->
<g id="edge79" class="edge"><title>N16&#45;&gt;N78</title>
<g id="a_edge79"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.deferproc (1.02s)">
<path fill="none" stroke="black" d="M1693.28,-1426.83C1700.71,-1421.44 1708.41,-1415.32 1715,-1409 1729.79,-1394.81 1744.07,-1376.82 1754.87,-1362.02"/>
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<g id="a_edge79&#45;label"><a xlink:title="github.com/biogo/hts/bam.newBuffer &#45;&gt; runtime.deferproc (1.02s)">
<text text-anchor="middle" x="1744" y="-1397.8" font-family="Times,serif" font-size="14.00"> 1.02s</text>
</a>
</g>
</g>
<!-- N18 -->
<g id="node19" class="node"><title>N18</title>
<g id="a_node19"><a xlink:title="runtime.scanobject (8.47s)">
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<text text-anchor="middle" x="2070" y="-584.8" font-family="Times,serif" font-size="14.00">runtime.scanobject</text>
<text text-anchor="middle" x="2070" y="-569.8" font-family="Times,serif" font-size="14.00">7.02s(3.23%)</text>
<text text-anchor="middle" x="2070" y="-554.8" font-family="Times,serif" font-size="14.00">of 8.47s(3.89%)</text>
</a>
</g>
</g>
<!-- N17&#45;&gt;N18 -->
<g id="edge18" class="edge"><title>N17&#45;&gt;N18</title>
<g id="a_edge18"><a xlink:title="runtime.gcDrain &#45;&gt; runtime.scanobject (7.11s)">
<path fill="none" stroke="black" d="M2022.43,-650.609C2029.92,-638.625 2039.67,-623.032 2048.39,-609.083"/>
<polygon fill="black" stroke="black" points="2051.6,-610.544 2053.93,-600.208 2045.66,-606.833 2051.6,-610.544"/>
</a>
</g>
<g id="a_edge18&#45;label"><a xlink:title="runtime.gcDrain &#45;&gt; runtime.scanobject (7.11s)">
<text text-anchor="middle" x="2058" y="-621.8" font-family="Times,serif" font-size="14.00"> 7.11s</text>
</a>
</g>
</g>
<!-- N55 -->
<g id="node56" class="node"><title>N55</title>
<g id="a_node56"><a xlink:title="runtime.markroot (1.45s)">
<polygon fill="#f8f8f8" stroke="black" points="1992,-592.5 1914,-592.5 1914,-554.5 1992,-554.5 1992,-592.5"/>
<text text-anchor="middle" x="1953" y="-581.3" font-family="Times,serif" font-size="9.00">runtime.markroot</text>
<text text-anchor="middle" x="1953" y="-571.3" font-family="Times,serif" font-size="9.00">0.07s(0.032%)</text>
<text text-anchor="middle" x="1953" y="-561.3" font-family="Times,serif" font-size="9.00">of 1.45s(0.67%)</text>
</a>
</g>
</g>
<!-- N17&#45;&gt;N55 -->
<g id="edge70" class="edge"><title>N17&#45;&gt;N55</title>
<g id="a_edge70"><a xlink:title="runtime.gcDrain &#45;&gt; runtime.markroot (1.26s)">
<path fill="none" stroke="black" d="M1978.47,-650.675C1972.51,-645.591 1966.93,-639.652 1963,-633 1957.63,-623.913 1954.96,-612.733 1953.69,-602.589"/>
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</g>
<g id="a_edge70&#45;label"><a xlink:title="runtime.gcDrain &#45;&gt; runtime.markroot (1.26s)">
<text text-anchor="middle" x="1980" y="-621.8" font-family="Times,serif" font-size="14.00"> 1.26s</text>
</a>
</g>
</g>
<!-- N54 -->
<g id="node55" class="node"><title>N54</title>
<g id="a_node55"><a xlink:title="runtime.heapBitsForObject (1.48s)">
<polygon fill="#f8f8f8" stroke="black" points="2145.5,-397 2008.5,-397 2008.5,-361 2145.5,-361 2145.5,-397"/>
<text text-anchor="middle" x="2077" y="-382.2" font-family="Times,serif" font-size="11.00">runtime.heapBitsForObject</text>
<text text-anchor="middle" x="2077" y="-370.2" font-family="Times,serif" font-size="11.00">1.48s(0.68%)</text>
</a>
</g>
</g>
<!-- N18&#45;&gt;N54 -->
<g id="edge86" class="edge"><title>N18&#45;&gt;N54</title>
<g id="a_edge86"><a xlink:title="runtime.scanobject &#45;&gt; runtime.heapBitsForObject (0.71s)">
<path fill="none" stroke="black" d="M2070.93,-546.937C2072.25,-510.635 2074.66,-444.431 2076.01,-407.235"/>
<polygon fill="black" stroke="black" points="2079.51,-407.245 2076.38,-397.124 2072.52,-406.99 2079.51,-407.245"/>
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</g>
<g id="a_edge86&#45;label"><a xlink:title="runtime.scanobject &#45;&gt; runtime.heapBitsForObject (0.71s)">
<text text-anchor="middle" x="2091" y="-470.3" font-family="Times,serif" font-size="14.00"> 0.71s</text>
</a>
</g>
</g>
<!-- N79 -->
<g id="node80" class="node"><title>N79</title>
<g id="a_node80"><a xlink:title="runtime.greyobject (1.13s)">
<polygon fill="#f8f8f8" stroke="black" points="2270,-401 2170,-401 2170,-357 2270,-357 2270,-401"/>
<text text-anchor="middle" x="2220" y="-388.2" font-family="Times,serif" font-size="11.00">runtime.greyobject</text>
<text text-anchor="middle" x="2220" y="-376.2" font-family="Times,serif" font-size="11.00">1.08s(0.5%)</text>
<text text-anchor="middle" x="2220" y="-364.2" font-family="Times,serif" font-size="11.00">of 1.13s(0.52%)</text>
</a>
</g>
</g>
<!-- N18&#45;&gt;N79 -->
<g id="edge83" class="edge"><title>N18&#45;&gt;N79</title>
<g id="a_edge83"><a xlink:title="runtime.scanobject &#45;&gt; runtime.greyobject (0.74s)">
<path fill="none" stroke="black" d="M2084.21,-546.66C2092.35,-531.839 2102.76,-512.88 2112,-496 2130.71,-461.803 2126.91,-447.034 2154,-419 2158.31,-414.54 2163.24,-410.412 2168.41,-406.642"/>
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</g>
<g id="a_edge83&#45;label"><a xlink:title="runtime.scanobject &#45;&gt; runtime.greyobject (0.74s)">
<text text-anchor="middle" x="2148" y="-470.3" font-family="Times,serif" font-size="14.00"> 0.74s</text>
</a>
</g>
</g>
<!-- N20 -->
<g id="node21" class="node"><title>N20</title>
<g id="a_node21"><a xlink:title="hash/crc32.ieeeInit.func1 (7.03s)">
<polygon fill="#f8f8f8" stroke="black" points="1342.5,-1466.5 1237.5,-1466.5 1237.5,-1428.5 1342.5,-1428.5 1342.5,-1466.5"/>
<text text-anchor="middle" x="1290" y="-1455.3" font-family="Times,serif" font-size="9.00">hash/crc32.ieeeInit.func1</text>
<text text-anchor="middle" x="1290" y="-1445.3" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="1290" y="-1435.3" font-family="Times,serif" font-size="9.00">of 7.03s(3.23%)</text>
</a>
</g>
</g>
<!-- N19&#45;&gt;N20 -->
<g id="edge21" class="edge"><title>N19&#45;&gt;N20</title>
<g id="a_edge21"><a xlink:title="hash/crc32.Update &#45;&gt; hash/crc32.ieeeInit.func1 (7.01s)">
<path fill="none" stroke="black" d="M1174.7,-1518.96C1185.91,-1513.46 1198.06,-1507.21 1209,-1501 1224.57,-1492.16 1241.25,-1481.55 1255.4,-1472.2"/>
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</g>
<g id="a_edge21&#45;label"><a xlink:title="hash/crc32.Update &#45;&gt; hash/crc32.ieeeInit.func1 (7.01s)">
<text text-anchor="middle" x="1249" y="-1489.8" font-family="Times,serif" font-size="14.00"> 7.01s</text>
</a>
</g>
</g>
<!-- N21 -->
<g id="node22" class="node"><title>N21</title>
<g id="a_node22"><a xlink:title="hash/crc32.slicingUpdate (7.02s)">
<polygon fill="#f8f8f8" stroke="black" points="1401,-1359.5 1247,-1359.5 1247,-1306.5 1401,-1306.5 1401,-1359.5"/>
<text text-anchor="middle" x="1324" y="-1344.3" font-family="Times,serif" font-size="14.00">hash/crc32.slicingUpdate</text>
<text text-anchor="middle" x="1324" y="-1329.3" font-family="Times,serif" font-size="14.00">7.01s(3.22%)</text>
<text text-anchor="middle" x="1324" y="-1314.3" font-family="Times,serif" font-size="14.00">of 7.02s(3.23%)</text>
</a>
</g>
</g>
<!-- N20&#45;&gt;N21 -->
<g id="edge20" class="edge"><title>N20&#45;&gt;N21</title>
<g id="a_edge20"><a xlink:title="hash/crc32.ieeeInit.func1 &#45;&gt; hash/crc32.slicingUpdate (7.02s)">
<path fill="none" stroke="black" d="M1295.46,-1428.42C1300.26,-1412.56 1307.37,-1389.02 1313.3,-1369.41"/>
<polygon fill="black" stroke="black" points="1316.73,-1370.16 1316.27,-1359.58 1310.03,-1368.14 1316.73,-1370.16"/>
</a>
</g>
<g id="a_edge20&#45;label"><a xlink:title="hash/crc32.ieeeInit.func1 &#45;&gt; hash/crc32.slicingUpdate (7.02s)">
<text text-anchor="middle" x="1322" y="-1397.8" font-family="Times,serif" font-size="14.00"> 7.02s</text>
</a>
</g>
</g>
<!-- N22&#45;&gt;N7 -->
<g id="edge80" class="edge"><title>N22&#45;&gt;N7</title>
<g id="a_edge80"><a xlink:title="compress/flate.(*decompressor).readHuffman &#45;&gt; compress/flate.(*decompressor).huffSym (0.97s)">
<path fill="none" stroke="black" d="M1026.9,-1312.39C998.913,-1295.93 956.835,-1272.64 918,-1257 905.084,-1251.8 891.553,-1246.86 877.847,-1242.21"/>
<polygon fill="black" stroke="black" points="878.929,-1238.88 868.336,-1239.04 876.716,-1245.52 878.929,-1238.88"/>
</a>
</g>
<g id="a_edge80&#45;label"><a xlink:title="compress/flate.(*decompressor).readHuffman &#45;&gt; compress/flate.(*decompressor).huffSym (0.97s)">
<text text-anchor="middle" x="967" y="-1260.8" font-family="Times,serif" font-size="14.00"> 0.97s</text>
</a>
</g>
</g>
<!-- N25 -->
<g id="node26" class="node"><title>N25</title>
<g id="a_node26"><a xlink:title="compress/flate.(*huffmanDecoder).init (5.19s)">
<polygon fill="#f8f8f8" stroke="black" points="1421.5,-1219.5 1222.5,-1219.5 1222.5,-1172.5 1421.5,-1172.5 1421.5,-1219.5"/>
<text text-anchor="middle" x="1322" y="-1205.9" font-family="Times,serif" font-size="12.00">compress/flate.(*huffmanDecoder).init</text>
<text text-anchor="middle" x="1322" y="-1192.9" font-family="Times,serif" font-size="12.00">3.15s(1.45%)</text>
<text text-anchor="middle" x="1322" y="-1179.9" font-family="Times,serif" font-size="12.00">of 5.19s(2.39%)</text>
</a>
</g>
</g>
<!-- N22&#45;&gt;N25 -->
<g id="edge24" class="edge"><title>N22&#45;&gt;N25</title>
<g id="a_edge24"><a xlink:title="compress/flate.(*decompressor).readHuffman &#45;&gt; compress/flate.(*huffmanDecoder).init (5.19s)">
<path fill="none" stroke="black" d="M1108.87,-1312.47C1128.69,-1305.01 1151.78,-1296.7 1173,-1290 1202.81,-1280.59 1213.61,-1287.07 1241,-1272 1261.92,-1260.49 1281.67,-1242.42 1296.43,-1226.89"/>
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<g id="a_edge24&#45;label"><a xlink:title="compress/flate.(*decompressor).readHuffman &#45;&gt; compress/flate.(*huffmanDecoder).init (5.19s)">
<text text-anchor="middle" x="1279" y="-1260.8" font-family="Times,serif" font-size="14.00"> 5.19s</text>
</a>
</g>
</g>
<!-- N23 -->
<g id="node24" class="node"><title>N23</title>
<g id="a_node24"><a xlink:title="runtime.morestack (5.50s)">
<polygon fill="#f8f8f8" stroke="black" points="2628,-690.5 2546,-690.5 2546,-652.5 2628,-652.5 2628,-690.5"/>
<text text-anchor="middle" x="2587" y="-679.3" font-family="Times,serif" font-size="9.00">runtime.morestack</text>
<text text-anchor="middle" x="2587" y="-669.3" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="2587" y="-659.3" font-family="Times,serif" font-size="9.00">of 5.50s(2.53%)</text>
</a>
</g>
</g>
<!-- N24 -->
<g id="node25" class="node"><title>N24</title>
<g id="a_node25"><a xlink:title="runtime.newstack (5.49s)">
<polygon fill="#f8f8f8" stroke="black" points="2626.5,-592.5 2547.5,-592.5 2547.5,-554.5 2626.5,-554.5 2626.5,-592.5"/>
<text text-anchor="middle" x="2587" y="-581.3" font-family="Times,serif" font-size="9.00">runtime.newstack</text>
<text text-anchor="middle" x="2587" y="-571.3" font-family="Times,serif" font-size="9.00">0.03s(0.014%)</text>
<text text-anchor="middle" x="2587" y="-561.3" font-family="Times,serif" font-size="9.00">of 5.49s(2.52%)</text>
</a>
</g>
</g>
<!-- N23&#45;&gt;N24 -->
<g id="edge23" class="edge"><title>N23&#45;&gt;N24</title>
<g id="a_edge23"><a xlink:title="runtime.morestack &#45;&gt; runtime.newstack (5.49s)">
<path fill="none" stroke="black" d="M2587,-652.443C2587,-638.586 2587,-619.186 2587,-603.208"/>
<polygon fill="black" stroke="black" points="2590.5,-602.802 2587,-592.802 2583.5,-602.802 2590.5,-602.802"/>
</a>
</g>
<g id="a_edge23&#45;label"><a xlink:title="runtime.morestack &#45;&gt; runtime.newstack (5.49s)">
<text text-anchor="middle" x="2604" y="-621.8" font-family="Times,serif" font-size="14.00"> 5.49s</text>
</a>
</g>
</g>
<!-- N34 -->
<g id="node35" class="node"><title>N34</title>
<g id="a_node35"><a xlink:title="runtime.goschedImpl (3.13s)">
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<text text-anchor="middle" x="2620" y="-481.8" font-family="Times,serif" font-size="9.00">runtime.goschedImpl</text>
<text text-anchor="middle" x="2620" y="-471.8" font-family="Times,serif" font-size="9.00">0.04s(0.018%)</text>
<text text-anchor="middle" x="2620" y="-461.8" font-family="Times,serif" font-size="9.00">of 3.13s(1.44%)</text>
</a>
</g>
</g>
<!-- N24&#45;&gt;N34 -->
<g id="edge32" class="edge"><title>N24&#45;&gt;N34</title>
<g id="a_edge32"><a xlink:title="runtime.newstack ... runtime.goschedImpl (2.77s)">
<path fill="none" stroke="black" stroke-dasharray="1,5" d="M2593.21,-554.161C2598.09,-539.726 2604.98,-519.367 2610.55,-502.911"/>
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</a>
</g>
<g id="a_edge32&#45;label"><a xlink:title="runtime.newstack ... runtime.goschedImpl (2.77s)">
<text text-anchor="middle" x="2623" y="-517.8" font-family="Times,serif" font-size="14.00"> 2.77s</text>
</a>
</g>
</g>
<!-- N41 -->
<g id="node42" class="node"><title>N41</title>
<g id="a_node42"><a xlink:title="runtime.copystack (2.42s)">
<polygon fill="#f8f8f8" stroke="black" points="2555.5,-493 2474.5,-493 2474.5,-455 2555.5,-455 2555.5,-493"/>
<text text-anchor="middle" x="2515" y="-481.8" font-family="Times,serif" font-size="9.00">runtime.copystack</text>
<text text-anchor="middle" x="2515" y="-471.8" font-family="Times,serif" font-size="9.00">0.03s(0.014%)</text>
<text text-anchor="middle" x="2515" y="-461.8" font-family="Times,serif" font-size="9.00">of 2.42s(1.11%)</text>
</a>
</g>
</g>
<!-- N24&#45;&gt;N41 -->
<g id="edge41" class="edge"><title>N24&#45;&gt;N41</title>
<g id="a_edge41"><a xlink:title="runtime.newstack &#45;&gt; runtime.copystack (2s)">
<path fill="none" stroke="black" d="M2573.46,-554.161C2562.5,-539.317 2546.91,-518.21 2534.59,-501.523"/>
<polygon fill="black" stroke="black" points="2537.24,-499.222 2528.48,-493.257 2531.61,-503.38 2537.24,-499.222"/>
</a>
</g>
<g id="a_edge41&#45;label"><a xlink:title="runtime.newstack &#45;&gt; runtime.copystack (2s)">
<text text-anchor="middle" x="2561" y="-517.8" font-family="Times,serif" font-size="14.00"> 2s</text>
</a>
</g>
</g>
<!-- N63 -->
<g id="node64" class="node"><title>N63</title>
<g id="a_node64"><a xlink:title="runtime.scanstack (1.35s)">
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<text text-anchor="middle" x="2416" y="-481.8" font-family="Times,serif" font-size="9.00">runtime.scanstack</text>
<text text-anchor="middle" x="2416" y="-471.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="2416" y="-461.8" font-family="Times,serif" font-size="9.00">of 1.35s(0.62%)</text>
</a>
</g>
</g>
<!-- N24&#45;&gt;N63 -->
<g id="edge90" class="edge"><title>N24&#45;&gt;N63</title>
<g id="a_edge90"><a xlink:title="runtime.newstack &#45;&gt; runtime.scanstack (0.62s)">
<path fill="none" stroke="black" d="M2552.51,-554.444C2538.06,-546.756 2521.13,-537.594 2506,-529 2488.76,-519.203 2469.91,-507.976 2453.93,-498.305"/>
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<g id="a_edge90&#45;label"><a xlink:title="runtime.newstack &#45;&gt; runtime.scanstack (0.62s)">
<text text-anchor="middle" x="2523" y="-517.8" font-family="Times,serif" font-size="14.00"> 0.62s</text>
</a>
</g>
</g>
<!-- N25&#45;&gt;N29 -->
<g id="edge43" class="edge"><title>N25&#45;&gt;N29</title>
<g id="a_edge43"><a xlink:title="compress/flate.(*huffmanDecoder).init &#45;&gt; runtime.makeslice (1.85s)">
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<g id="a_edge43&#45;label"><a xlink:title="compress/flate.(*huffmanDecoder).init &#45;&gt; runtime.makeslice (1.85s)">
<text text-anchor="middle" x="1325" y="-1123.8" font-family="Times,serif" font-size="14.00"> 1.85s</text>
</a>
</g>
</g>
<!-- N26&#45;&gt;N15 -->
<g id="edge25" class="edge"><title>N26&#45;&gt;N15</title>
<g id="a_edge25"><a xlink:title="runtime.newobject &#45;&gt; runtime.mallocgc (5s)">
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<g id="a_edge25&#45;label"><a xlink:title="runtime.newobject &#45;&gt; runtime.mallocgc (5s)">
<text text-anchor="middle" x="1785" y="-995.8" font-family="Times,serif" font-size="14.00"> 5s</text>
</a>
</g>
</g>
<!-- N28 -->
<g id="node29" class="node"><title>N28</title>
<g id="a_node29"><a xlink:title="github.com/biogo/hts/bgzf.(*decompressor).nextBlockAt (4.60s)">
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<text text-anchor="middle" x="903" y="-1637.8" font-family="Times,serif" font-size="9.00">github.com/biogo/hts/bgzf.(*decompressor).nextBlockAt</text>
<text text-anchor="middle" x="903" y="-1627.8" font-family="Times,serif" font-size="9.00">0.04s(0.018%)</text>
<text text-anchor="middle" x="903" y="-1617.8" font-family="Times,serif" font-size="9.00">of 4.60s(2.12%)</text>
</a>
</g>
</g>
<!-- N27&#45;&gt;N28 -->
<g id="edge27" class="edge"><title>N27&#45;&gt;N28</title>
<g id="a_edge27"><a xlink:title="github.com/biogo/hts/bgzf.NewReader.func1 &#45;&gt; github.com/biogo/hts/bgzf.(*decompressor).nextBlockAt (4.60s)">
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<g id="a_edge27&#45;label"><a xlink:title="github.com/biogo/hts/bgzf.NewReader.func1 &#45;&gt; github.com/biogo/hts/bgzf.(*decompressor).nextBlockAt (4.60s)">
<text text-anchor="middle" x="920" y="-1673.8" font-family="Times,serif" font-size="14.00"> 4.60s</text>
</a>
</g>
</g>
<!-- N69 -->
<g id="node70" class="node"><title>N69</title>
<g id="a_node70"><a xlink:title="compress/gzip.(*Reader).Reset (1.28s)">
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<text text-anchor="middle" x="1388" y="-1545.8" font-family="Times,serif" font-size="9.00">compress/gzip.(*Reader).Reset</text>
<text text-anchor="middle" x="1388" y="-1535.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="1388" y="-1525.8" font-family="Times,serif" font-size="9.00">of 1.28s(0.59%)</text>
</a>
</g>
</g>
<!-- N28&#45;&gt;N69 -->
<g id="edge66" class="edge"><title>N28&#45;&gt;N69</title>
<g id="a_edge66"><a xlink:title="github.com/biogo/hts/bgzf.(*decompressor).nextBlockAt ... compress/gzip.(*Reader).Reset (1.28s)">
<path fill="none" stroke="black" stroke-dasharray="1,5" d="M1000.27,-1610.95C1093.01,-1593.74 1230.61,-1568.21 1314.51,-1552.64"/>
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</g>
<g id="a_edge66&#45;label"><a xlink:title="github.com/biogo/hts/bgzf.(*decompressor).nextBlockAt ... compress/gzip.(*Reader).Reset (1.28s)">
<text text-anchor="middle" x="1206" y="-1578.8" font-family="Times,serif" font-size="14.00"> 1.28s</text>
</a>
</g>
</g>
<!-- N29&#45;&gt;N15 -->
<g id="edge29" class="edge"><title>N29&#45;&gt;N15</title>
<g id="a_edge29"><a xlink:title="runtime.makeslice &#45;&gt; runtime.mallocgc (4.20s)">
<path fill="none" stroke="black" d="M1308.34,-1043C1323.51,-1026.38 1347.65,-1003.43 1374,-992 1402.55,-979.612 1591.17,-963.175 1693.4,-955.025"/>
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</a>
</g>
<g id="a_edge29&#45;label"><a xlink:title="runtime.makeslice &#45;&gt; runtime.mallocgc (4.20s)">
<text text-anchor="middle" x="1391" y="-995.8" font-family="Times,serif" font-size="14.00"> 4.20s</text>
</a>
</g>
</g>
<!-- N31 -->
<g id="node32" class="node"><title>N31</title>
<g id="a_node32"><a xlink:title="io.ReadAtLeast (4.22s)">
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<text text-anchor="middle" x="1557" y="-1204.5" font-family="Times,serif" font-size="10.00">io.ReadAtLeast</text>
<text text-anchor="middle" x="1557" y="-1193.5" font-family="Times,serif" font-size="10.00">0.28s(0.13%)</text>
<text text-anchor="middle" x="1557" y="-1182.5" font-family="Times,serif" font-size="10.00">of 4.22s(1.94%)</text>
</a>
</g>
</g>
<!-- N30&#45;&gt;N31 -->
<g id="edge28" class="edge"><title>N30&#45;&gt;N31</title>
<g id="a_edge28"><a xlink:title="io.ReadFull &#45;&gt; io.ReadAtLeast (4.22s)">
<path fill="none" stroke="black" d="M1557,-1313.79C1557,-1291.53 1557,-1253.53 1557,-1226.94"/>
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</g>
<g id="a_edge28&#45;label"><a xlink:title="io.ReadFull &#45;&gt; io.ReadAtLeast (4.22s)">
<text text-anchor="middle" x="1574" y="-1260.8" font-family="Times,serif" font-size="14.00"> 4.22s</text>
</a>
</g>
</g>
<!-- N40 -->
<g id="node41" class="node"><title>N40</title>
<g id="a_node41"><a xlink:title="github.com/biogo/hts/bgzf.(*Reader).Read (2.50s)">
<polygon fill="#f8f8f8" stroke="black" points="1735.5,-1084 1544.5,-1084 1544.5,-1043 1735.5,-1043 1735.5,-1084"/>
<text text-anchor="middle" x="1640" y="-1072" font-family="Times,serif" font-size="10.00">github.com/biogo/hts/bgzf.(*Reader).Read</text>
<text text-anchor="middle" x="1640" y="-1061" font-family="Times,serif" font-size="10.00">0.75s(0.34%)</text>
<text text-anchor="middle" x="1640" y="-1050" font-family="Times,serif" font-size="10.00">of 2.50s(1.15%)</text>
</a>
</g>
</g>
<!-- N31&#45;&gt;N40 -->
<g id="edge36" class="edge"><title>N31&#45;&gt;N40</title>
<g id="a_edge36"><a xlink:title="io.ReadAtLeast &#45;&gt; github.com/biogo/hts/bgzf.(*Reader).Read (2.50s)">
<path fill="none" stroke="black" d="M1559.76,-1175.31C1562.66,-1159.43 1568.35,-1137.03 1579,-1120 1585.76,-1109.19 1595.2,-1099.18 1604.64,-1090.73"/>
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<g id="a_edge36&#45;label"><a xlink:title="io.ReadAtLeast &#45;&gt; github.com/biogo/hts/bgzf.(*Reader).Read (2.50s)">
<text text-anchor="middle" x="1596" y="-1123.8" font-family="Times,serif" font-size="14.00"> 2.50s</text>
</a>
</g>
</g>
<!-- N59 -->
<g id="node60" class="node"><title>N59</title>
<g id="a_node60"><a xlink:title="github.com/biogo/hts/bgzf.(*countReader).Read (1.41s)">
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<text text-anchor="middle" x="1441" y="-1066.1" font-family="Times,serif" font-size="8.00">github.com/biogo/hts/bgzf.(*countReader).Read</text>
<text text-anchor="middle" x="1441" y="-1057.1" font-family="Times,serif" font-size="8.00">0 of 1.41s(0.65%)</text>
</a>
</g>
</g>
<!-- N31&#45;&gt;N59 -->
<g id="edge87" class="edge"><title>N31&#45;&gt;N59</title>
<g id="a_edge87"><a xlink:title="io.ReadAtLeast &#45;&gt; github.com/biogo/hts/bgzf.(*countReader).Read (0.70s)">
<path fill="none" stroke="black" d="M1542.98,-1175.25C1531.68,-1159.74 1515.08,-1137.86 1499,-1120 1489.27,-1109.19 1477.83,-1097.96 1467.69,-1088.46"/>
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<g id="a_edge87&#45;label"><a xlink:title="io.ReadAtLeast &#45;&gt; github.com/biogo/hts/bgzf.(*countReader).Read (0.70s)">
<text text-anchor="middle" x="1528" y="-1123.8" font-family="Times,serif" font-size="14.00"> 0.70s</text>
</a>
</g>
</g>
<!-- N32 -->
<g id="node33" class="node"><title>N32</title>
<g id="a_node33"><a xlink:title="runtime.schedule (4.21s)">
<polygon fill="#f8f8f8" stroke="black" points="2658.5,-398 2581.5,-398 2581.5,-360 2658.5,-360 2658.5,-398"/>
<text text-anchor="middle" x="2620" y="-386.8" font-family="Times,serif" font-size="9.00">runtime.schedule</text>
<text text-anchor="middle" x="2620" y="-376.8" font-family="Times,serif" font-size="9.00">0.10s(0.046%)</text>
<text text-anchor="middle" x="2620" y="-366.8" font-family="Times,serif" font-size="9.00">of 4.21s(1.94%)</text>
</a>
</g>
</g>
<!-- N52 -->
<g id="node53" class="node"><title>N52</title>
<g id="a_node53"><a xlink:title="runtime.gcstopm (1.61s)">
<polygon fill="#f8f8f8" stroke="black" points="2617,-304.5 2541,-304.5 2541,-266.5 2617,-266.5 2617,-304.5"/>
<text text-anchor="middle" x="2579" y="-293.3" font-family="Times,serif" font-size="9.00">runtime.gcstopm</text>
<text text-anchor="middle" x="2579" y="-283.3" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="2579" y="-273.3" font-family="Times,serif" font-size="9.00">of 1.61s(0.74%)</text>
</a>
</g>
</g>
<!-- N32&#45;&gt;N52 -->
<g id="edge51" class="edge"><title>N32&#45;&gt;N52</title>
<g id="a_edge51"><a xlink:title="runtime.schedule &#45;&gt; runtime.gcstopm (1.57s)">
<path fill="none" stroke="black" d="M2611.9,-359.923C2606,-346.764 2597.91,-328.713 2591.23,-313.802"/>
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</a>
</g>
<g id="a_edge51&#45;label"><a xlink:title="runtime.schedule &#45;&gt; runtime.gcstopm (1.57s)">
<text text-anchor="middle" x="2618" y="-327.8" font-family="Times,serif" font-size="14.00"> 1.57s</text>
</a>
</g>
</g>
<!-- N66 -->
<g id="node67" class="node"><title>N66</title>
<g id="a_node67"><a xlink:title="runtime.findrunnable (1.31s)">
<polygon fill="#f8f8f8" stroke="black" points="2738.5,-306 2635.5,-306 2635.5,-265 2738.5,-265 2738.5,-306"/>
<text text-anchor="middle" x="2687" y="-294" font-family="Times,serif" font-size="10.00">runtime.findrunnable</text>
<text text-anchor="middle" x="2687" y="-283" font-family="Times,serif" font-size="10.00">0.38s(0.17%)</text>
<text text-anchor="middle" x="2687" y="-272" font-family="Times,serif" font-size="10.00">of 1.31s(0.6%)</text>
</a>
</g>
</g>
<!-- N32&#45;&gt;N66 -->
<g id="edge63" class="edge"><title>N32&#45;&gt;N66</title>
<g id="a_edge63"><a xlink:title="runtime.schedule &#45;&gt; runtime.findrunnable (1.31s)">
<path fill="none" stroke="black" d="M2633.24,-359.923C2642.74,-346.948 2655.72,-329.218 2666.55,-314.432"/>
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</g>
<g id="a_edge63&#45;label"><a xlink:title="runtime.schedule &#45;&gt; runtime.findrunnable (1.31s)">
<text text-anchor="middle" x="2676" y="-327.8" font-family="Times,serif" font-size="14.00"> 1.31s</text>
</a>
</g>
</g>
<!-- N33 -->
<g id="node34" class="node"><title>N33</title>
<g id="a_node34"><a xlink:title="runtime.gentraceback (3.14s)">
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<text text-anchor="middle" x="2511" y="-387.5" font-family="Times,serif" font-size="10.00">runtime.gentraceback</text>
<text text-anchor="middle" x="2511" y="-376.5" font-family="Times,serif" font-size="10.00">0.39s(0.18%)</text>
<text text-anchor="middle" x="2511" y="-365.5" font-family="Times,serif" font-size="10.00">of 3.14s(1.44%)</text>
</a>
</g>
</g>
<!-- N34&#45;&gt;N32 -->
<g id="edge33" class="edge"><title>N34&#45;&gt;N32</title>
<g id="a_edge33"><a xlink:title="runtime.goschedImpl &#45;&gt; runtime.schedule (2.73s)">
<path fill="none" stroke="black" d="M2620,-454.626C2620,-441.421 2620,-423.369 2620,-408.327"/>
<polygon fill="black" stroke="black" points="2623.5,-408.019 2620,-398.019 2616.5,-408.019 2623.5,-408.019"/>
</a>
</g>
<g id="a_edge33&#45;label"><a xlink:title="runtime.goschedImpl &#45;&gt; runtime.schedule (2.73s)">
<text text-anchor="middle" x="2637" y="-422.8" font-family="Times,serif" font-size="14.00"> 2.73s</text>
</a>
</g>
</g>
<!-- N35&#45;&gt;N13 -->
<g id="edge61" class="edge"><title>N35&#45;&gt;N13</title>
<g id="a_edge61"><a xlink:title="compress/flate.(*dictDecoder).writeCopy &#45;&gt; runtime.memmove (1.34s)">
<path fill="none" stroke="black" d="M1053.52,-1173.74C1074.76,-1151.75 1108.04,-1117.28 1131.53,-1092.95"/>
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<g id="a_edge61&#45;label"><a xlink:title="compress/flate.(*dictDecoder).writeCopy &#45;&gt; runtime.memmove (1.34s)">
<text text-anchor="middle" x="1121" y="-1123.8" font-family="Times,serif" font-size="14.00"> 1.34s</text>
</a>
</g>
</g>
<!-- N36 -->
<g id="node37" class="node"><title>N36</title>
<g id="a_node37"><a xlink:title="runtime.writebarrierptr_prewrite1 (2.92s)">
<polygon fill="#f8f8f8" stroke="black" points="2040.5,-1084 1887.5,-1084 1887.5,-1043 2040.5,-1043 2040.5,-1084"/>
<text text-anchor="middle" x="1964" y="-1072" font-family="Times,serif" font-size="10.00">runtime.writebarrierptr_prewrite1</text>
<text text-anchor="middle" x="1964" y="-1061" font-family="Times,serif" font-size="10.00">0.44s(0.2%)</text>
<text text-anchor="middle" x="1964" y="-1050" font-family="Times,serif" font-size="10.00">of 2.92s(1.34%)</text>
</a>
</g>
</g>
<!-- N36&#45;&gt;N9 -->
<g id="edge37" class="edge"><title>N36&#45;&gt;N9</title>
<g id="a_edge37"><a xlink:title="runtime.writebarrierptr_prewrite1 &#45;&gt; runtime.systemstack (2.48s)">
<path fill="none" stroke="black" d="M1967.02,-1042.95C1974.88,-992.01 1996.03,-854.973 2005.41,-794.209"/>
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<g id="a_edge37&#45;label"><a xlink:title="runtime.writebarrierptr_prewrite1 &#45;&gt; runtime.systemstack (2.48s)">
<text text-anchor="middle" x="2007" y="-894.8" font-family="Times,serif" font-size="14.00"> 2.48s</text>
</a>
</g>
</g>
<!-- N37 -->
<g id="node38" class="node"><title>N37</title>
<g id="a_node38"><a xlink:title="runtime.futex (2.65s)">
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<text text-anchor="middle" x="2573" y="-21.4" font-family="Times,serif" font-size="12.00">runtime.futex</text>
<text text-anchor="middle" x="2573" y="-8.4" font-family="Times,serif" font-size="12.00">2.65s(1.22%)</text>
</a>
</g>
</g>
<!-- N38&#45;&gt;N36 -->
<g id="edge35" class="edge"><title>N38&#45;&gt;N36</title>
<g id="a_edge35"><a xlink:title="runtime.writebarrierptr &#45;&gt; runtime.writebarrierptr_prewrite1 (2.53s)">
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<polygon fill="black" stroke="black" points="1967.5,-1094.2 1964,-1084.2 1960.5,-1094.2 1967.5,-1094.2"/>
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</g>
<g id="a_edge35&#45;label"><a xlink:title="runtime.writebarrierptr &#45;&gt; runtime.writebarrierptr_prewrite1 (2.53s)">
<text text-anchor="middle" x="1981" y="-1123.8" font-family="Times,serif" font-size="14.00"> 2.53s</text>
</a>
</g>
</g>
<!-- N42 -->
<g id="node43" class="node"><title>N42</title>
<g id="a_node43"><a xlink:title="runtime.gcmarkwb_m (2.41s)">
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<text text-anchor="middle" x="2258" y="-582" font-family="Times,serif" font-size="10.00">runtime.gcmarkwb_m</text>
<text text-anchor="middle" x="2258" y="-571" font-family="Times,serif" font-size="10.00">0.71s(0.33%)</text>
<text text-anchor="middle" x="2258" y="-560" font-family="Times,serif" font-size="10.00">of 2.41s(1.11%)</text>
</a>
</g>
</g>
<!-- N39&#45;&gt;N42 -->
<g id="edge38" class="edge"><title>N39&#45;&gt;N42</title>
<g id="a_edge38"><a xlink:title="runtime.writebarrierptr_prewrite1.func1 &#45;&gt; runtime.gcmarkwb_m (2.41s)">
<path fill="none" stroke="black" d="M2258,-650.609C2258,-637.262 2258,-619.439 2258,-604.396"/>
<polygon fill="black" stroke="black" points="2261.5,-604.037 2258,-594.037 2254.5,-604.037 2261.5,-604.037"/>
</a>
</g>
<g id="a_edge38&#45;label"><a xlink:title="runtime.writebarrierptr_prewrite1.func1 &#45;&gt; runtime.gcmarkwb_m (2.41s)">
<text text-anchor="middle" x="2275" y="-621.8" font-family="Times,serif" font-size="14.00"> 2.41s</text>
</a>
</g>
</g>
<!-- N41&#45;&gt;N33 -->
<g id="edge39" class="edge"><title>N41&#45;&gt;N33</title>
<g id="a_edge39"><a xlink:title="runtime.copystack &#45;&gt; runtime.gentraceback (2.18s)">
<path fill="none" stroke="black" d="M2514.21,-454.626C2513.66,-441.847 2512.92,-424.529 2512.28,-409.792"/>
<polygon fill="black" stroke="black" points="2515.77,-409.46 2511.84,-399.62 2508.78,-409.761 2515.77,-409.46"/>
</a>
</g>
<g id="a_edge39&#45;label"><a xlink:title="runtime.copystack &#45;&gt; runtime.gentraceback (2.18s)">
<text text-anchor="middle" x="2530" y="-422.8" font-family="Times,serif" font-size="14.00"> 2.18s</text>
</a>
</g>
</g>
<!-- N47 -->
<g id="node48" class="node"><title>N47</title>
<g id="a_node48"><a xlink:title="runtime.shade (1.70s)">
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<text text-anchor="middle" x="2233" y="-482.5" font-family="Times,serif" font-size="10.00">runtime.shade</text>
<text text-anchor="middle" x="2233" y="-471.5" font-family="Times,serif" font-size="10.00">0.58s(0.27%)</text>
<text text-anchor="middle" x="2233" y="-460.5" font-family="Times,serif" font-size="10.00">of 1.70s(0.78%)</text>
</a>
</g>
</g>
<!-- N42&#45;&gt;N47 -->
<g id="edge48" class="edge"><title>N42&#45;&gt;N47</title>
<g id="a_edge48"><a xlink:title="runtime.gcmarkwb_m &#45;&gt; runtime.shade (1.70s)">
<path fill="none" stroke="black" d="M2252.94,-552.769C2249.38,-538.893 2244.56,-520.085 2240.55,-504.441"/>
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</a>
</g>
<g id="a_edge48&#45;label"><a xlink:title="runtime.gcmarkwb_m &#45;&gt; runtime.shade (1.70s)">
<text text-anchor="middle" x="2263" y="-517.8" font-family="Times,serif" font-size="14.00"> 1.70s</text>
</a>
</g>
</g>
<!-- N43 -->
<g id="node44" class="node"><title>N43</title>
<g id="a_node44"><a xlink:title="runtime.mcall (1.93s)">
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<text text-anchor="middle" x="1098" y="-1949.8" font-family="Times,serif" font-size="9.00">runtime.mcall</text>
<text text-anchor="middle" x="1098" y="-1939.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="1098" y="-1929.8" font-family="Times,serif" font-size="9.00">of 1.93s(0.89%)</text>
</a>
</g>
</g>
<!-- N44&#45;&gt;N9 -->
<g id="edge46" class="edge"><title>N44&#45;&gt;N9</title>
<g id="a_edge46"><a xlink:title="runtime.(*mcache).nextFree &#45;&gt; runtime.systemstack (1.72s)">
<path fill="none" stroke="black" d="M1910.61,-834.86C1917.44,-824.312 1927.07,-811.305 1938,-802 1943.46,-797.352 1949.59,-793.07 1955.92,-789.193"/>
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</a>
</g>
<g id="a_edge46&#45;label"><a xlink:title="runtime.(*mcache).nextFree &#45;&gt; runtime.systemstack (1.72s)">
<text text-anchor="middle" x="1955" y="-805.8" font-family="Times,serif" font-size="14.00"> 1.72s</text>
</a>
</g>
</g>
<!-- N45 -->
<g id="node46" class="node"><title>N45</title>
<g id="a_node46"><a xlink:title="runtime.futexwakeup (1.77s)">
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<text text-anchor="middle" x="2573" y="-113.8" font-family="Times,serif" font-size="9.00">runtime.futexwakeup</text>
<text text-anchor="middle" x="2573" y="-103.8" font-family="Times,serif" font-size="9.00">0.08s(0.037%)</text>
<text text-anchor="middle" x="2573" y="-93.8" font-family="Times,serif" font-size="9.00">of 1.77s(0.81%)</text>
</a>
</g>
</g>
<!-- N45&#45;&gt;N37 -->
<g id="edge49" class="edge"><title>N45&#45;&gt;N37</title>
<g id="a_edge49"><a xlink:title="runtime.futexwakeup &#45;&gt; runtime.futex (1.69s)">
<path fill="none" stroke="black" d="M2573,-86.7616C2573,-74.9344 2573,-59.3159 2573,-46.0547"/>
<polygon fill="black" stroke="black" points="2576.5,-46.0422 2573,-36.0422 2569.5,-46.0423 2576.5,-46.0422"/>
</a>
</g>
<g id="a_edge49&#45;label"><a xlink:title="runtime.futexwakeup &#45;&gt; runtime.futex (1.69s)">
<text text-anchor="middle" x="2590" y="-57.8" font-family="Times,serif" font-size="14.00"> 1.69s</text>
</a>
</g>
</g>
<!-- N46&#45;&gt;N9 -->
<g id="edge47" class="edge"><title>N46&#45;&gt;N9</title>
<g id="a_edge47"><a xlink:title="runtime.gcAssistAlloc &#45;&gt; runtime.systemstack (1.70s)">
<path fill="none" stroke="black" d="M1473.73,-834.925C1479.68,-823.404 1489.08,-809.312 1502,-802 1540.18,-780.397 1824.36,-769.754 1950.26,-766.059"/>
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</g>
<g id="a_edge47&#45;label"><a xlink:title="runtime.gcAssistAlloc &#45;&gt; runtime.systemstack (1.70s)">
<text text-anchor="middle" x="1519" y="-805.8" font-family="Times,serif" font-size="14.00"> 1.70s</text>
</a>
</g>
</g>
<!-- N47&#45;&gt;N54 -->
<g id="edge88" class="edge"><title>N47&#45;&gt;N54</title>
<g id="a_edge88"><a xlink:title="runtime.shade &#45;&gt; runtime.heapBitsForObject (0.68s)">
<path fill="none" stroke="black" d="M2199.92,-453.277C2174.87,-438.348 2140.46,-417.834 2114.42,-402.307"/>
<polygon fill="black" stroke="black" points="2115.97,-399.155 2105.58,-397.041 2112.38,-405.168 2115.97,-399.155"/>
</a>
</g>
<g id="a_edge88&#45;label"><a xlink:title="runtime.shade &#45;&gt; runtime.heapBitsForObject (0.68s)">
<text text-anchor="middle" x="2181" y="-422.8" font-family="Times,serif" font-size="14.00"> 0.68s</text>
</a>
</g>
</g>
<!-- N47&#45;&gt;N79 -->
<g id="edge96" class="edge"><title>N47&#45;&gt;N79</title>
<g id="a_edge96"><a xlink:title="runtime.shade &#45;&gt; runtime.greyobject (0.30s)">
<path fill="none" stroke="black" d="M2230.24,-453.277C2228.54,-441.125 2226.33,-425.273 2224.39,-411.422"/>
<polygon fill="black" stroke="black" points="2227.83,-410.733 2222.98,-401.314 2220.9,-411.702 2227.83,-410.733"/>
</a>
</g>
<g id="a_edge96&#45;label"><a xlink:title="runtime.shade &#45;&gt; runtime.greyobject (0.30s)">
<text text-anchor="middle" x="2244" y="-422.8" font-family="Times,serif" font-size="14.00"> 0.30s</text>
</a>
</g>
</g>
<!-- N48&#45;&gt;N38 -->
<g id="edge93" class="edge"><title>N48&#45;&gt;N38</title>
<g id="a_edge93"><a xlink:title="runtime.deferreturn &#45;&gt; runtime.writebarrierptr (0.37s)">
<path fill="none" stroke="black" d="M1956.31,-1312.37C1957.83,-1289.49 1960.37,-1251.49 1962.11,-1225.39"/>
<polygon fill="black" stroke="black" points="1965.6,-1225.56 1962.78,-1215.35 1958.62,-1225.1 1965.6,-1225.56"/>
</a>
</g>
<g id="a_edge93&#45;label"><a xlink:title="runtime.deferreturn &#45;&gt; runtime.writebarrierptr (0.37s)">
<text text-anchor="middle" x="1976" y="-1260.8" font-family="Times,serif" font-size="14.00"> 0.37s</text>
</a>
</g>
</g>
<!-- N49 -->
<g id="node50" class="node"><title>N49</title>
<g id="a_node50"><a xlink:title="runtime.pcvalue (1.67s)">
<polygon fill="#f8f8f8" stroke="black" points="1819.5,-1962.5 1736.5,-1962.5 1736.5,-1921.5 1819.5,-1921.5 1819.5,-1962.5"/>
<text text-anchor="middle" x="1778" y="-1950.5" font-family="Times,serif" font-size="10.00">runtime.pcvalue</text>
<text text-anchor="middle" x="1778" y="-1939.5" font-family="Times,serif" font-size="10.00">0.64s(0.29%)</text>
<text text-anchor="middle" x="1778" y="-1928.5" font-family="Times,serif" font-size="10.00">of 1.67s(0.77%)</text>
</a>
</g>
</g>
<!-- N50&#45;&gt;N18 -->
<g id="edge58" class="edge"><title>N50&#45;&gt;N18</title>
<g id="a_edge58"><a xlink:title="runtime.gcDrainN &#45;&gt; runtime.scanobject (1.36s)">
<path fill="none" stroke="black" d="M2102.48,-652.443C2097.43,-640.324 2090.61,-623.966 2084.53,-609.364"/>
<polygon fill="black" stroke="black" points="2087.74,-607.969 2080.66,-600.084 2081.28,-610.661 2087.74,-607.969"/>
</a>
</g>
<g id="a_edge58&#45;label"><a xlink:title="runtime.gcDrainN &#45;&gt; runtime.scanobject (1.36s)">
<text text-anchor="middle" x="2110" y="-621.8" font-family="Times,serif" font-size="14.00"> 1.36s</text>
</a>
</g>
</g>
<!-- N51 -->
<g id="node52" class="node"><title>N51</title>
<g id="a_node52"><a xlink:title="runtime.memclrNoHeapPointers (1.63s)">
<polygon fill="#f8f8f8" stroke="black" points="2258.5,-1743 2097.5,-1743 2097.5,-1707 2258.5,-1707 2258.5,-1743"/>
<text text-anchor="middle" x="2178" y="-1728.2" font-family="Times,serif" font-size="11.00">runtime.memclrNoHeapPointers</text>
<text text-anchor="middle" x="2178" y="-1716.2" font-family="Times,serif" font-size="11.00">1.63s(0.75%)</text>
</a>
</g>
</g>
<!-- N53 -->
<g id="node54" class="node"><title>N53</title>
<g id="a_node54"><a xlink:title="runtime.notewakeup (1.54s)">
<polygon fill="#f8f8f8" stroke="black" points="2617.5,-214 2528.5,-214 2528.5,-176 2617.5,-176 2617.5,-214"/>
<text text-anchor="middle" x="2573" y="-202.8" font-family="Times,serif" font-size="9.00">runtime.notewakeup</text>
<text text-anchor="middle" x="2573" y="-192.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="2573" y="-182.8" font-family="Times,serif" font-size="9.00">of 1.54s(0.71%)</text>
</a>
</g>
</g>
<!-- N52&#45;&gt;N53 -->
<g id="edge95" class="edge"><title>N52&#45;&gt;N53</title>
<g id="a_edge95"><a xlink:title="runtime.gcstopm &#45;&gt; runtime.notewakeup (0.30s)">
<path fill="none" stroke="black" d="M2576.14,-266.233C2575.3,-260.132 2574.48,-253.287 2574,-247 2573.45,-239.762 2573.15,-231.93 2572.99,-224.627"/>
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</a>
</g>
<g id="a_edge95&#45;label"><a xlink:title="runtime.gcstopm &#45;&gt; runtime.notewakeup (0.30s)">
<text text-anchor="middle" x="2591" y="-235.8" font-family="Times,serif" font-size="14.00"> 0.30s</text>
</a>
</g>
</g>
<!-- N57 -->
<g id="node58" class="node"><title>N57</title>
<g id="a_node58"><a xlink:title="runtime.stopm (1.44s)">
<polygon fill="#f8f8f8" stroke="black" points="2717,-213 2643,-213 2643,-177 2717,-177 2717,-213"/>
<text text-anchor="middle" x="2680" y="-197.6" font-family="Times,serif" font-size="8.00">runtime.stopm</text>
<text text-anchor="middle" x="2680" y="-188.6" font-family="Times,serif" font-size="8.00">0 of 1.44s(0.66%)</text>
</a>
</g>
</g>
<!-- N52&#45;&gt;N57 -->
<g id="edge78" class="edge"><title>N52&#45;&gt;N57</title>
<g id="a_edge78"><a xlink:title="runtime.gcstopm &#45;&gt; runtime.stopm (1.08s)">
<path fill="none" stroke="black" d="M2599.93,-266.163C2615.22,-252.762 2636.1,-234.465 2652.71,-219.916"/>
<polygon fill="black" stroke="black" points="2655.26,-222.336 2660.47,-213.113 2650.64,-217.071 2655.26,-222.336"/>
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</g>
<g id="a_edge78&#45;label"><a xlink:title="runtime.gcstopm &#45;&gt; runtime.stopm (1.08s)">
<text text-anchor="middle" x="2655" y="-235.8" font-family="Times,serif" font-size="14.00"> 1.08s</text>
</a>
</g>
</g>
<!-- N53&#45;&gt;N45 -->
<g id="edge52" class="edge"><title>N53&#45;&gt;N45</title>
<g id="a_edge52"><a xlink:title="runtime.notewakeup &#45;&gt; runtime.futexwakeup (1.52s)">
<path fill="none" stroke="black" d="M2573,-175.974C2573,-164.192 2573,-148.561 2573,-135.158"/>
<polygon fill="black" stroke="black" points="2576.5,-135.003 2573,-125.003 2569.5,-135.003 2576.5,-135.003"/>
</a>
</g>
<g id="a_edge52&#45;label"><a xlink:title="runtime.notewakeup &#45;&gt; runtime.futexwakeup (1.52s)">
<text text-anchor="middle" x="2590" y="-146.8" font-family="Times,serif" font-size="14.00"> 1.52s</text>
</a>
</g>
</g>
<!-- N56 -->
<g id="node57" class="node"><title>N56</title>
<g id="a_node57"><a xlink:title="runtime.(*mheap).alloc (1.44s)">
<polygon fill="#f8f8f8" stroke="black" points="2227,-1961 2129,-1961 2129,-1923 2227,-1923 2227,-1961"/>
<text text-anchor="middle" x="2178" y="-1949.8" font-family="Times,serif" font-size="9.00">runtime.(*mheap).alloc</text>
<text text-anchor="middle" x="2178" y="-1939.8" font-family="Times,serif" font-size="9.00">0.03s(0.014%)</text>
<text text-anchor="middle" x="2178" y="-1929.8" font-family="Times,serif" font-size="9.00">of 1.44s(0.66%)</text>
</a>
</g>
</g>
<!-- N56&#45;&gt;N51 -->
<g id="edge55" class="edge"><title>N56&#45;&gt;N51</title>
<g id="a_edge55"><a xlink:title="runtime.(*mheap).alloc &#45;&gt; runtime.memclrNoHeapPointers (1.41s)">
<path fill="none" stroke="black" d="M2178,-1922.67C2178,-1884.77 2178,-1797.62 2178,-1753.16"/>
<polygon fill="black" stroke="black" points="2181.5,-1753.08 2178,-1743.08 2174.5,-1753.08 2181.5,-1753.08"/>
</a>
</g>
<g id="a_edge55&#45;label"><a xlink:title="runtime.(*mheap).alloc &#45;&gt; runtime.memclrNoHeapPointers (1.41s)">
<text text-anchor="middle" x="2195" y="-1768.8" font-family="Times,serif" font-size="14.00"> 1.41s</text>
</a>
</g>
</g>
<!-- N58 -->
<g id="node59" class="node"><title>N58</title>
<g id="a_node59"><a xlink:title="bufio.(*Reader).Read (1.41s)">
<polygon fill="#f8f8f8" stroke="black" points="1439.5,-968 1346.5,-968 1346.5,-930 1439.5,-930 1439.5,-968"/>
<text text-anchor="middle" x="1393" y="-956.8" font-family="Times,serif" font-size="9.00">bufio.(*Reader).Read</text>
<text text-anchor="middle" x="1393" y="-946.8" font-family="Times,serif" font-size="9.00">0.05s(0.023%)</text>
<text text-anchor="middle" x="1393" y="-936.8" font-family="Times,serif" font-size="9.00">of 1.41s(0.65%)</text>
</a>
</g>
</g>
<!-- N68 -->
<g id="node69" class="node"><title>N68</title>
<g id="a_node69"><a xlink:title="os.(*File).Read (1.29s)">
<polygon fill="#f8f8f8" stroke="black" points="1399.5,-873 1324.5,-873 1324.5,-835 1399.5,-835 1399.5,-873"/>
<text text-anchor="middle" x="1362" y="-861.8" font-family="Times,serif" font-size="9.00">os.(*File).Read</text>
<text text-anchor="middle" x="1362" y="-851.8" font-family="Times,serif" font-size="9.00">0.02s(0.0092%)</text>
<text text-anchor="middle" x="1362" y="-841.8" font-family="Times,serif" font-size="9.00">of 1.29s(0.59%)</text>
</a>
</g>
</g>
<!-- N58&#45;&gt;N68 -->
<g id="edge65" class="edge"><title>N58&#45;&gt;N68</title>
<g id="a_edge65"><a xlink:title="bufio.(*Reader).Read &#45;&gt; os.(*File).Read (1.29s)">
<path fill="none" stroke="black" d="M1386.88,-929.626C1382.43,-916.293 1376.34,-898.018 1371.3,-882.89"/>
<polygon fill="black" stroke="black" points="1374.49,-881.399 1368.01,-873.019 1367.85,-883.613 1374.49,-881.399"/>
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</g>
<g id="a_edge65&#45;label"><a xlink:title="bufio.(*Reader).Read &#45;&gt; os.(*File).Read (1.29s)">
<text text-anchor="middle" x="1396" y="-894.8" font-family="Times,serif" font-size="14.00"> 1.29s</text>
</a>
</g>
</g>
<!-- N59&#45;&gt;N58 -->
<g id="edge54" class="edge"><title>N59&#45;&gt;N58</title>
<g id="a_edge54"><a xlink:title="github.com/biogo/hts/bgzf.(*countReader).Read &#45;&gt; bufio.(*Reader).Read (1.41s)">
<path fill="none" stroke="black" d="M1433.71,-1045.41C1426.06,-1027.48 1413.91,-998.996 1404.87,-977.814"/>
<polygon fill="black" stroke="black" points="1407.98,-976.195 1400.84,-968.371 1401.54,-978.942 1407.98,-976.195"/>
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</g>
<g id="a_edge54&#45;label"><a xlink:title="github.com/biogo/hts/bgzf.(*countReader).Read &#45;&gt; bufio.(*Reader).Read (1.41s)">
<text text-anchor="middle" x="1434" y="-995.8" font-family="Times,serif" font-size="14.00"> 1.41s</text>
</a>
</g>
</g>
<!-- N61 -->
<g id="node62" class="node"><title>N61</title>
<g id="a_node62"><a xlink:title="runtime.(*mcache).refill (1.36s)">
<polygon fill="#f8f8f8" stroke="black" points="1895.5,-592.5 1794.5,-592.5 1794.5,-554.5 1895.5,-554.5 1895.5,-592.5"/>
<text text-anchor="middle" x="1845" y="-581.3" font-family="Times,serif" font-size="9.00">runtime.(*mcache).refill</text>
<text text-anchor="middle" x="1845" y="-571.3" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="1845" y="-561.3" font-family="Times,serif" font-size="9.00">of 1.36s(0.63%)</text>
</a>
</g>
</g>
<!-- N60&#45;&gt;N61 -->
<g id="edge57" class="edge"><title>N60&#45;&gt;N61</title>
<g id="a_edge57"><a xlink:title="runtime.(*mcache).nextFree.func1 &#45;&gt; runtime.(*mcache).refill (1.36s)">
<path fill="none" stroke="black" d="M1851.5,-652.443C1850.34,-638.586 1848.72,-619.186 1847.39,-603.208"/>
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</a>
</g>
<g id="a_edge57&#45;label"><a xlink:title="runtime.(*mcache).nextFree.func1 &#45;&gt; runtime.(*mcache).refill (1.36s)">
<text text-anchor="middle" x="1866" y="-621.8" font-family="Times,serif" font-size="14.00"> 1.36s</text>
</a>
</g>
</g>
<!-- N62 -->
<g id="node63" class="node"><title>N62</title>
<g id="a_node63"><a xlink:title="runtime.(*mcentral).cacheSpan (1.35s)">
<polygon fill="#f8f8f8" stroke="black" points="1916.5,-494.5 1773.5,-494.5 1773.5,-453.5 1916.5,-453.5 1916.5,-494.5"/>
<text text-anchor="middle" x="1845" y="-482.5" font-family="Times,serif" font-size="10.00">runtime.(*mcentral).cacheSpan</text>
<text text-anchor="middle" x="1845" y="-471.5" font-family="Times,serif" font-size="10.00">0.26s(0.12%)</text>
<text text-anchor="middle" x="1845" y="-460.5" font-family="Times,serif" font-size="10.00">of 1.35s(0.62%)</text>
</a>
</g>
</g>
<!-- N61&#45;&gt;N62 -->
<g id="edge60" class="edge"><title>N61&#45;&gt;N62</title>
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<text text-anchor="middle" x="1862" y="-517.8" font-family="Times,serif" font-size="14.00"> 1.35s</text>
</a>
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<!-- N63&#45;&gt;N33 -->
<g id="edge81" class="edge"><title>N63&#45;&gt;N33</title>
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<text text-anchor="middle" x="2486" y="-422.8" font-family="Times,serif" font-size="14.00"> 0.84s</text>
</a>
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<!-- N77 -->
<g id="node78" class="node"><title>N77</title>
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<text text-anchor="middle" x="1813" y="-1445.3" font-family="Times,serif" font-size="9.00">0.09s(0.041%)</text>
<text text-anchor="middle" x="1813" y="-1435.3" font-family="Times,serif" font-size="9.00">of 1.21s(0.56%)</text>
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<text text-anchor="middle" x="1448" y="-1445.3" font-family="Times,serif" font-size="9.00">0.03s(0.014%)</text>
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<!-- N71 -->
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<!-- N70&#45;&gt;N71 -->
<g id="edge68" class="edge"><title>N70&#45;&gt;N71</title>
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<!-- N72 -->
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<text text-anchor="middle" x="1362" y="-571.3" font-family="Times,serif" font-size="9.00">0.01s(0.0046%)</text>
<text text-anchor="middle" x="1362" y="-561.3" font-family="Times,serif" font-size="9.00">of 1.27s(0.58%)</text>
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<!-- N71&#45;&gt;N72 -->
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<!-- N73 -->
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<text text-anchor="middle" x="1362" y="-471.2" font-family="Times,serif" font-size="11.00">1.20s(0.55%)</text>
<text text-anchor="middle" x="1362" y="-459.2" font-family="Times,serif" font-size="11.00">of 1.26s(0.58%)</text>
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<!-- N72&#45;&gt;N73 -->
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<text text-anchor="middle" x="1639" y="-847.6" font-family="Times,serif" font-size="8.00">0 of 1.25s(0.57%)</text>
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<!-- N75&#45;&gt;N9 -->
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<!-- N76&#45;&gt;N29 -->
<g id="edge98" class="edge"><title>N76&#45;&gt;N29</title>
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Raw
flagstat.go
// Copyright ©2017 The bíogo Authors. All rights reserved.
// Use of this source code is governed by a BSD-style
// license that can be found in the LICENSE file.
// This program tabulates statistics on a bam file from the sam flag.
// It replicates functionality in samtools flagstat.
package main
import (
"flag"
"fmt"
"io"
"log"
"os"
"runtime/pprof"
"github.com/biogo/hts/bam"
"github.com/biogo/hts/bgzf"
"github.com/biogo/hts/sam"
)
const (
pass = iota
fail
)
var cpuprofile = flag.String("cpuprofile", "", "write cpu profile to file")
func main() {
flag.Parse()
if len(flag.Args()) != 1 {
log.Fatal("Expecting a single bam argument")
}
if *cpuprofile != "" {
f, err := os.Create(*cpuprofile)
if err != nil {
log.Fatal(err)
}
defer f.Close()
pprof.StartCPUProfile(f)
defer pprof.StopCPUProfile()
}
f, err := os.Open(flag.Args()[0])
if err != nil {
log.Fatal(err)
}
defer f.Close()
ok, err := bgzf.HasEOF(f)
if err != nil {
log.Fatal(err)
}
if !ok {
log.Println("EOF block missing")
}
b, err := bam.NewReader(f, 0)
if err != nil {
log.Fatal(err)
}
defer b.Close()
b.Omit(bam.AllVariableLengthData)
// counts is indexed by [pass/fail][sam.Flag] where we have 12 possible sam Flags.
var counts [2][12]uint64
// track mates on different chromosomes.
var mates [2]struct{ allMapQ, highMapQ uint64 }
var good, singletons, paired [2]uint64
var qc int
for {
read, err := b.Read()
if err == io.EOF {
break
}
if err != nil {
log.Fatal(err)
}
if read.Flags&sam.QCFail == 0 {
qc = pass
} else {
qc = fail
}
for i := Paired; i <= Supplementary; i++ {
if read.Flags&(1<<i) != 0 {
counts[qc][i]++
}
}
const goodMask = sam.ProperPair | sam.Unmapped
if read.Flags&goodMask == sam.ProperPair {
good[qc]++
}
const mapMask = sam.MateUnmapped | sam.Unmapped
switch read.Flags & mapMask {
case sam.MateUnmapped:
singletons[qc]++
case 0:
paired[qc]++
if read.MateRef != read.Ref && read.MateRef != nil && read.Ref != nil {
if read.MapQ > 4 {
mates[qc].highMapQ++
}
mates[qc].allMapQ++
}
}
}
// extract counts to match output from samtools flagstat.
fmt.Printf("%d + %d in total (QC-passed reads + QC-failed reads)\n", counts[pass][Paired], counts[fail][Paired])
fmt.Printf("%d + %d in total secondary\n", counts[pass][Secondary], counts[fail][Secondary])
fmt.Printf("%d + %d in total supplementary\n", counts[pass][Supplementary], counts[fail][Supplementary])
fmt.Printf("%d + %d duplicates\n", counts[pass][Duplicate], counts[fail][Duplicate])
mappedPass := counts[pass][Paired] - counts[pass][Unmapped]
mappedFail := counts[fail][Paired] - counts[fail][Unmapped]
fmt.Printf("%d + %d mapped (%s : %s)\n", mappedPass, mappedFail, percent(mappedPass, counts[pass][Paired]), percent(mappedFail, counts[fail][Paired]))
fmt.Printf("%d + %d paired in sequencing\n", counts[pass][Paired], counts[fail][Paired])
fmt.Printf("%d + %d read1\n", counts[pass][Read1], counts[fail][Read1])
fmt.Printf("%d + %d read2\n", counts[pass][Read2], counts[fail][Read2])
fmt.Printf("%d + %d properly paired (%s : %s)\n", good[pass], good[fail], percent(good[pass], counts[pass][Paired]), percent(good[fail], counts[fail][Paired]))
fmt.Printf("%d + %d with itself and mate mapped\n", paired[pass], paired[fail])
fmt.Printf("%d + %d singletons (%s : %s)\n", singletons[pass], singletons[fail], percent(singletons[pass], counts[pass][Paired]), percent(singletons[fail], counts[fail][Paired]))
fmt.Printf("%d + %d with mate mapped to a different chr\n", mates[pass].allMapQ, mates[fail].allMapQ)
fmt.Printf("%d + %d with mate mapped to a different chr (mapQ>=5)\n", mates[pass].highMapQ, mates[fail].highMapQ)
}
func percent(n, total uint64) string {
if total == 0 {
return "N/A"
}
return fmt.Sprintf("%.2f%%", 100*float64(n)/float64(total))
}
// The flag indexes for SAM flags. Reflects sam.Flag order.
const (
Paired uint = iota // The read is paired in sequencing, no matter whether it is mapped in a pair.
ProperPair // The read is mapped in a proper pair.
Unmapped // The read itself is unmapped; conflictive with ProperPair.
MateUnmapped // The mate is unmapped.
Reverse // The read is mapped to the reverse strand.
MateReverse // The mate is mapped to the reverse strand.
Read1 // This is read1.
Read2 // This is read2.
Secondary // Not primary alignment.
QCFail // QC failure.
Duplicate // Optical or PCR duplicate.
Supplementary // Supplementary alignment, indicates alignment is part of a chimeric alignment.
)
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