python.py

# my_module/
# 	__init__.py
# 	Helpers/
# 		__init__.py
# 		plist_helper.py
# 	Foo/
# 		__init__.py
# 		foo.py
# 		Bar/
# 			__init__.py
# 			bar.py
# 			Bazz/
# 				__init__.py
# 				bazz.py
#
# From 'bazz.py' I want to import 'plist_helper.py', how do i do this?

import my_module.Helpers.plist_helper

Unless you're not planning to put this in the import path, or you want to explicitly load that file and not something potentially distributed, in which case you're probably stuck with:

os.path.insert(0, __file__ + '../../../Helpers')
import plist_helper

I've attempted to do the first suggestion and I get back "ImportError: No module named my_module.Helpers.plist_helper", I would rather not do absolute path loading but everything else i've tried cannot find the top-level module.

from ....Helpers import plist_helper

(but already told you this on IRC :D)