NewTabMostVisitedRemoval.user.js

// ==UserScript==
// @name         NewTabMostVisitedRemoval
// @namespace    http://tampermonkey.net/
// @version      0.1
// @description  remove elements from newtab
// @author       Sean Vikoren
// @match           https://*/*
// @run-at          document-end
// @grant           GM_getValue
// @grant           GM_setValue
// @grant           GM_deleteValue
// ==/UserScript==
/* jshint -W097 */
'use strict';

// Remove Elements
const REGEXP = /^https?:\/\/www.google.[a-z.]+\/\_\/chrome\/newtab.*/;
var isDefaultNewTab = REGEXP.test(top.location.href);
//var isDefaultNewTab = false;

if (isDefaultNewTab) {  // If default new tab
    var killList = ['most-visited'];

    for (var i = 0; i < killList.length; i++) {
        var killMe = document.getElementById(killList[i]);
        if (killMe) {
            killMe.parentNode.removeChild(killMe);
        }
    }
}