Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Eden's Blessing | Unlocked a new item. | Defeat Hush as Eden | 188 |
3 | 20.5% | |
Eden's Soul | Unlocked a new item. | Defeat Delirium as Eden | 289 |
3 | 16.4% | |
Everything Jar | Complete the final chapter with Eden. | Defeat The Beast as Eden | 459 |
3 | 10.9% | |
Blank Card | Unlocked a new item. | Defeat Isaac as Eden | 121 |
2 | 30.1% | |
Undefined | Unlocked a new item. | Complete the Boss Rush as Eden | 125 |
2 | 25.8% | |
Mystery Sack | Unlocked a new item. | Defeat The Lamb as Eden | 124 |
2 | 23.3% | |
Book of Secrets | Unlocked a new item. | Defeat Satan as Eden | 122 |
1 | 28.6% | |
GB Bug | Unlocked a new item. | Defeat Ultra Greed as Eden | 201 |
1 | 23.7% | |
Metronome | Unlocked a new item. | Defeat Ultra Greedier as Eden | 303 |
1 | 14.3% | |
Mysterious Paper | Unlocked a new item. | Defeat ??? as Eden | 123 |
25.5% | ||
Yellow Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Eden | 214 |
18.9% | ||
'M | Complete the Corpse with Eden. | Defeat Mother as Eden | 458 |
9.6% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Book of Virtues | Complete the Cathedral with Bethany. | Defeat Isaac as Bethany | 417 |
3 | 15.2% | |
Urn of Souls | Complete Sheol with Bethany. | Defeat Satan as Bethany | 418 |
3 | 13.5% | |
Star of Bethlehem | Beat the Void with Bethany. | Defeat Delirium as Bethany | 425 |
3 | 10.8% | |
Alabaster Box | Complete the Dark Room with Bethany. | Defeat The Lamb as Bethany | 420 |
2 | 12% | |
Divine Intervention | Complete ??? with Bethany. | Defeat Hush as Bethany | 423 |
2 | 11.5% | |
Jar of Wisps | Complete the final chapter with Bethany. | Defeat The Beast as Bethany | 471 |
2 | 9.9% | |
Vade Retro | Beat Greedier mode with Bethany. | Defeat Ultra Greedier as Bethany | 424 |
2 | 9.8% | |
Soul Locket | Beat Greed mode with Bethany. | Defeat Ultra Greed as Bethany | 422 |
1 | 13.4% | |
Blessed Penny | Complete the Chest with Bethany. | Defeat ??? as Bethany | 419 |
13.1% | ||
Beth's Faith | Complete Boss Rush with Bethany. | Complete the Boss Rush as Bethany | 421 |
12.3% | ||
Glowing Baby | Defeat Mega Satan with Bethany. | Defeat Mega Satan as Bethany | 427 |
12% | ||
Baptism by Fire | Unlocked a new challenge. | Defeat Satan as Bethany, defeat Mom's Heart 11 times, and unlock Maggy's Faith | 509 |
11.6% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Purity | Unlocked a new item. | Defeat Hush as Magdalene | 180 |
3 | 19.5% | |
Eucharist | Unlocked a new item. | Defeat Delirium as Magdalene | 283 |
3 | 16.3% | |
Guardian Angel | Unlocked a new item. | Defeat Satan as Magdalene | 45 |
2 | 28.6% | |
Maggy's Bow | Unlocked a new item. | Complete the Boss Rush as Magdalene | 109 |
2 | 24.7% | |
Celtic Cross | Unlocked a new item. | Defeat ??? as Magdalene | 50 |
1 | 25% | |
Candy Heart | Complete the final chapter with Magdalene. | Defeat The Beast as Magdalene | 443 |
1 | 11.1% | |
Yuck Heart | Complete the Corpse with Magdalene. | Defeat Mother as Magdalene | 442 |
1 | 10% | |
Maggy's Faith | Unlocked a new item. | Defeat The Lamb as Magdalene | 71 |
23.5% | ||
Red Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Magdalene | 206 |
18.8% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Divorce Papers | Unlocked a new item. | Complete the Boss Rush as The Forgotten | 397 |
3 | 13.8% | |
Book of the Dead | Unlocked a new item. | Defeat Delirium as The Forgotten | 401 |
3 | 12.3% | |
Dad's Ring | Unlocked a new item. | Defeat Ultra Greedier as The Forgotten | 400 |
3 | 11.2% | |
Spirit Shackles | Complete the final chapter with the Forgotten. | Defeat The Beast as The Forgotten | 469 |
2 | 9.2% | |
Bone Spurs | Complete the Corpse with the Forgotten. | Defeat Mother as The Forgotten | 468 |
2 | 8.2% | |
Finger Bone | Unlocked a new item. | Defeat Ultra Greed as The Forgotten | 399 |
13.7% | ||
Bound Baby | Unlocked a new co-player baby. | Defeat Mega Satan as The Forgotten | 403 |
13% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Godhead | Unlocked a new item. | Earn all 5 / 9 (except Ultra Greed) / 10 / 12 Completion Marks on Hard mode as The Lost | 156 |
4 | 14% | |
The Body | Unlocked a new item. | Defeat ??? as The Lost | 131 |
3 | 18% | |
Sworn Protector | Unlocked a new item. | Defeat Hush as The Lost | 189 |
3 | 15.9% | |
Lost Soul | Complete the Corpse with the Lost. | Defeat Mother as The Lost | 460 |
2 | 9.2% | |
White Baby | Unlocked a new co-player baby. | Defeat Mega Satan as The Lost | 215 |
14.9% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Fate | Unlocked a new item. | Defeat ??? as ??? | 113 |
3 | 24.5% | |
Eternal D6 | Complete the Corpse with ???. | Defeat Mother as ??? | 448 |
3 | 8.3% | |
Fate's Reward | Unlocked a new item. | Defeat Hush as ??? | 183 |
2 | 18.8% | |
Montezuma's Revenge | Complete the final chapter with ???. | Defeat The Beast as ??? | 449 |
2 | 9.7% | |
???'s Only Friend | Unlocked a new item. | Complete the Boss Rush as ??? | 114 |
1 | 22.1% | |
King Baby | Unlocked a new co-player baby. | Defeat Delirium as ??? | 286 |
1 | 14.6% | |
???'s Soul | Unlocked a new item. | Defeat The Lamb as ??? | 73 |
20.7% | ||
Cracked Dice | Unlocked a new item. | Defeat Ultra Greed as ??? | 196 |
20.2% | ||
Blue Baby | Unlocked a new co-player baby. | Defeat Mega Satan as ??? | 209 |
17.1% | ||
Meconium | Unlocked a new item. | Defeat Ultra Greedier as ??? | 300 |
12.7% | ||
Hive Baby | Unlocked a new co-player baby. | Earn all Hard mode Completion Marks as ??? | 252 |
11.8% | ||
The Soiled | ??? | Use Red Key (etc.) to open the hidden closet in Home as ??? | 478 |
10.6% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Eve's Mascara | Unlocked a new item. | Complete the Boss Rush as Eve | 112 |
3 | 23.2% | |
Athame | Unlocked a new item. | Defeat Hush as Eve | 184 |
3 | 18.1% | |
Sacrificial Dagger | Unlocked a new item. | Defeat ??? as Eve | 53 |
2 | 23.3% | |
Dull Razor | Unlocked a new item. | Defeat Delirium as Eve | 288 |
1 | 14.2% | |
Cracked Orb | Complete the final chapter with Eve. | Defeat The Beast as Eve | 451 |
1 | 9.7% | |
Bird Cage | Complete the Corpse with Eve. | Defeat Mother as Eve | 450 |
1 | 8.3% | |
The Razor | Unlocked a new item. | Defeat Satan as Eve | 44 |
0 | 25.6% | |
Darkness Falls | Unlocked Challenge #4. | Defeat Mom's Heart 11 times and unlock Eve Defeat Mom's Heart 11 times and defeat ??? as Eve |
157 |
37.5% | ||
Eve's Bird Foot | Unlocked a new item. | Defeat Isaac as Eve | 76 |
26.3% | ||
Black Lipstick | Unlocked a new item. | Defeat The Lamb as Eve | 111 |
21.2% | ||
Lil' Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Eve | 210 |
16.3% | ||
Crow Heart | Unlocked a new item. | Defeat Ultra Greedier as Eve | 302 |
13.2% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Compound Fracture | Unlocked a new item. | Defeat Delirium as Lazarus | 291 |
3 | 14.7% | |
Pandora's Box | Unlocked a new item. | Defeat The Lamb as Lazarus | 119 |
2 | 21.4% | |
Empty Vessel | Unlocked a new item. | Defeat Hush as Lazarus | 187 |
2 | 18% | |
Astral Projection | Complete the final chapter with Lazarus. | Defeat The Beast as Lazarus | 457 |
2 | 9.7% | |
Lazarus' Rags | Unlocked a new item. | Defeat Isaac as Lazarus | 116 |
1 | 27.4% | |
Tinytoma | Complete the Corpse with Lazarus. | Defeat Mother as Lazarus | 456 |
1 | 8.4% | |
Missing No. | Unlocked a new item. | Complete the Boss Rush as Lazarus | 105 |
0 | 23.1% | |
Broken Ankh | Unlocked a new item. | Defeat Satan as Lazarus | 117 |
26.8% | ||
Store Credit | Unlocked a new item. | Defeat ??? as Lazarus | 118 |
23.4% | ||
Long Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Lazarus | 213 |
16.8% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Keeper's Sack | Complete the Corpse with Keeper. | Defeat Mother as Keeper | 464 |
3 | 7.5% | |
Deep Pockets | Unlocked a new item. | Defeat ??? as Keeper | 238 |
2 | 14.3% | |
Eye of Greed | Unlocked a new item. | Defeat Ultra Greedier as Keeper | 308 |
2 | 12.4% | |
Crooked Penny | Unlocked a new item. | Defeat Delirium as Keeper | 294 |
2 | 11.5% | |
Keeper's Box | Complete the final chapter with Keeper. | Defeat The Beast as Keeper | 465 |
2 | 8.6% | |
Super Greed Baby | Unlocked a new co-player baby. | Defeat Mom's Heart on Hard mode as Keeper | 241 |
15.1% | ||
Keeper holds Wooden Nickel | Unlocked a new starting item. | Defeat Isaac as Keeper | 236 |
14.9% | ||
Rib of Greed | Unlocked a new item. | Defeat Ultra Greed as Keeper | 204 |
14.2% | ||
Keeper holds Store Key | Unlocked a new starting item. | Defeat Satan as Keeper | 237 |
13.8% | ||
Sticky Nickels | Unlocked a new item. | Complete the Boss Rush as Keeper | 240 |
13.6% | ||
Keeper now holds... A Penny! | Unlocked a new item. | Defeat Hush as Keeper | 191 |
13.4% | ||
Noose Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Keeper | 217 |
13.4% | ||
Karma | Unlocked a new item. | Defeat The Lamb as Keeper | 239 |
13.4% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Void | Unlocked a new item. | Defeat Delirium as Apollyon | 295 |
4 | 14.3% | |
Worm Friend | Complete the final chapter with Apollyon. | Defeat The Beast as Apollyon | 467 |
3 | 9.2% | |
Smelter | Unlocked a new item. | Defeat Mom's Heart or It Lives! on Hard mode as Apollyon | 318 |
2 | 19.5% | |
Lil Portal | Complete the Corpse with Apollyon. | Defeat Mother as Apollyon | 466 |
1 | 7.7% | |
Brown Nugget | Unlocked a new item. | Defeat Ultra Greed as Apollyon | 316 |
0 | 16.3% | |
Hushy | Unlocked a new item. | Defeat Hush as Apollyon | 315 |
0 | 15% | |
Locust of Wrath | Unlocked a new item. | Defeat Isaac as Apollyon | 310 |
19.1% | ||
Locust of Famine | Unlocked a new item. | Defeat ??? as Apollyon | 312 |
17.6% | ||
Locust of Pestilence | Unlocked a new item. | Defeat Satan as Apollyon | 311 |
17.2% | ||
Locust of Death | Unlocked a new item. | Defeat The Lamb as Apollyon | 313 |
15.8% | ||
Locust of Conquest | Unlocked a new item. | Complete the Boss Rush as Apollyon | 314 |
15.6% | ||
Mort Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Apollyon | 317 |
14.9% | ||
Black Rune | Unlocked a new item. | Defeat Ultra Greedier as Apollyon | 309 |
12.6% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Judas' Shadow | Unlocked a new item. | Complete the Boss Rush as Judas | 108 |
3 | 27.6% | |
Guillotine | Unlocked a new item. | Defeat Isaac as Judas | 107 |
2 | 31% | |
Redemption | Complete the final chapter with Judas. | Defeat The Beast as Judas | 447 |
2 | 11.7% | |
Akeldama | Complete the Corpse with Judas. | Defeat Mother as Judas | 446 |
2 | 10% | |
Betrayal | Unlocked a new item. | Defeat Hush as Judas | 182 |
1 | 21.8% | |
Shade | Unlocked a new item. | Defeat Delirium as Judas | 285 |
0 | 17.1% | |
Curved Horn | Unlocked a new item. | Defeat The Lamb as Judas | 52 |
24.5% | ||
Brown Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Judas | 208 |
19.6% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Abaddon | Unlocked a new item. | Defeat ??? as Azazel | 128 |
3 | 29.8% | |
Maw of the Void | Unlocked a new item. | Defeat Hush as Azazel | 186 |
3 | 27% | |
Lil Abaddon | Complete the final chapter with Azazel. | Defeat The Beast as Azazel | 455 |
2 | 12.3% | |
Dark Prince's Crown | Unlocked a new item. | Defeat Delirium as Azazel | 290 |
1 | 19.5% | |
Devil's Crown | Complete the Corpse with Azazel. | Defeat Mother as Azazel | 454 |
13% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Rune Bag | Unlocked a new item. | Defeat Isaac as Lilith | 218 |
3 | 21.3% | |
Euthanasia | Unlocked a new item. | Defeat Delirium as Lilith | 292 |
3 | 13.8% | |
Cambion Conception | Unlocked a new item. | Defeat ??? as Lilith | 219 |
2 | 18.9% | |
Blood Puppy | Complete the Corpse with Lilith. | Defeat Mother as Lilith | 462 |
1 | 7.9% | |
Big Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Lilith | 216 |
16% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Spindown Dice | ??? | Defeat Delirium as Tainted Isaac | 584 |
4 | 8.3% | |
Glitched Crown | ??? | Defeat The Beast as Tainted Isaac | 491 |
4 | 8.1% | |
Soul of Isaac | ??? | Defeat Hush and Boss Rush as Tainted Isaac | 618 |
8.1% | ||
Mom's Lock | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Isaac | 548 |
7.7% | ||
The Stars | ??? | Defeat Ultra Greedier as Tainted Isaac | 541 |
7.6% | ||
Dice Bag | ??? | Defeat Mother as Tainted Isaac | 549 |
6.9% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Abyss | ??? | Defeat Delirium as Tainted Apollyon | 597 |
4 | 5.5% | |
Echo Chamber | ??? | Defeat The Beast as Tainted Apollyon | 504 |
3 | 5.4% | |
Rotten Beggar | ??? | Defeat Mega Satan as Tainted Apollyon | 614 |
5.8% | ||
Cricket Leg | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Apollyon | 574 |
5.4% | ||
Soul of Apollyon | ??? | Defeat Hush and Boss Rush as Tainted Apollyon | 631 |
5.4% | ||
The Tower | ??? | Defeat Ultra Greedier as Tainted Apollyon | 540 |
5.3% | ||
Apollyon's Best Friend | ??? | Defeat Mother as Tainted Apollyon | 575 |
5% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Flip | ??? | Defeat Delirium as Tainted Lazarus | 592 |
4 | 4.1% | |
Salvation | ??? | Defeat The Beast as Tainted Lazarus | 499 |
3 | 3.9% | |
Wooden Chest | ??? | Defeat Mega Satan as Tainted Lazarus | 609 |
4.3% | ||
Judgement | ??? | Defeat Ultra Greedier as Tainted Lazarus | 543 |
4.2% | ||
Torn Pocket | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Lazarus | 564 |
4% | ||
Torn Card | ??? | Defeat Mother as Tainted Lazarus | 565 |
3.9% | ||
Soul of Lazarus | ??? | Defeat Hush and Boss Rush as Tainted Lazarus | 626 |
3.9% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Sacred Orb | ??? | Defeat The Beast as Tainted Lost | 501 |
4 | 5.7% | |
Ghost Bombs | ??? | Defeat Delirium as Tainted Lost | 594 |
2 | 5.5% | |
Soul of the Lost | ??? | Defeat Hush and Boss Rush as Tainted Lost | 628 |
6% | ||
Haunted Chest | ??? | Defeat Mega Satan as Tainted Lost | 611 |
5.7% | ||
Kid's Drawing | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Lost | 568 |
5.5% | ||
The Fool | ??? | Defeat Ultra Greedier as Tainted Lost | 524 |
5.4% | ||
Crystal Key | ??? | Defeat Mother as Tainted Lost | 569 |
5.2% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Sumptorium | ??? | Defeat Delirium as Tainted Eve | 589 |
3 | 4.9% | |
Heartbreak | ??? | Defeat The Beast as Tainted Eve | 496 |
3 | 4.3% | |
Horse Pill | ??? | Defeat Mega Satan as Tainted Eve | 606 |
5.1% | ||
Soul of Eve | ??? | Defeat Hush and Boss Rush as Tainted Eve | 623 |
4.7% | ||
The Empress | ??? | Defeat Ultra Greedier as Tainted Eve | 527 |
4.6% | ||
Strange Key | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Eve | 558 |
4.6% | ||
Lil Clot | ??? | Defeat Mother as Tainted Eve | 559 |
4.3% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Bloody Lust | Unlocked a new item. | Defeat Isaac as Samson | 54 |
2 | 28.2% | |
Bloody Gust | Complete the Corpse with Samson. | Defeat Mother as Samson | 452 |
2 | 8.5% | |
Samson's Chains | Unlocked a new item. | Complete the Boss Rush as Samson | 115 |
1 | 25% | |
Empty Heart | Complete the final chapter with Samson. | Defeat The Beast as Samson | 453 |
1 | 10.1% | |
Blood Penny | Unlocked a new item. | Defeat ??? as Samson | 55 |
23.8% | ||
Rage Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Samson | 211 |
17.2% | ||
Bloody Crown | Unlocked a new item. | Defeat Delirium as Samson | 287 |
14.7% | ||
Stem Cell | Unlocked a new item. | Defeat Ultra Greedier as Samson | 301 |
13.7% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Cain's Other Eye | Unlocked a new item. | Complete the Boss Rush as Cain | 110 |
2 | 27.4% | |
Guppy's Eye | Complete the Corpse with Cain. | Defeat Mother as Cain | 444 |
2 | 11% | |
D12 | Unlocked a new item. | Defeat Hush as Cain | 181 |
1 | 21.4% | |
A Pound of Flesh | Complete the final chapter with Cain. | Defeat The Beast as Cain | 445 |
1 | 12.2% | |
Cain's Eye | Unlocked a new item. | Defeat ??? as Cain | 75 |
26.4% | ||
Green Baby | Unlocked a new co-player baby. | Defeat Mega Satan as Cain | 207 |
19.9% | ||
Silver Dollar | Unlocked a new item. | Defeat Delirium as Cain | 284 |
17.2% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Belly Jelly | ??? | Defeat The Beast as Tainted Magdalene | 492 |
3 | 5.1% | |
Hypercoagulation | ??? | Defeat Delirium as Tainted Magdalene | 585 |
2 | 5.6% | |
The Lovers | ??? | Defeat Ultra Greedier as Tainted Magdalene | 530 |
5.9% | ||
Queen of Hearts | ??? | Defeat Mega Satan as Tainted Magdalene | 602 |
5.9% | ||
Soul of Magdalene | ??? | Defeat Hush and Boss Rush as Tainted Magdalene | 619 |
5.8% | ||
Holy Crown | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Magdalene | 550 |
5.4% | ||
Mother's Kiss | ??? | Defeat Mother as Tainted Magdalene | 551 |
5% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Isaac's Tomb | ??? | Defeat The Beast as Tainted Forgotten | 505 |
3 | 5% | |
Decap Attack | ??? | Defeat Delirium as Tainted Forgotten | 598 |
2 | 5.2% | |
Golden Battery | ??? | Defeat Mega Satan as Tainted Forgotten | 615 |
5.7% | ||
Soul of the Forgotten | ??? | Defeat Hush and Boss Rush as Tainted Forgotten | 632 |
5.5% | ||
Polished Bone | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Forgotten | 576 |
5.1% | ||
Death | ??? | Defeat Ultra Greedier as Tainted Forgotten | 537 |
5% | ||
Hollow Heart | ??? | Defeat Mother as Tainted Forgotten | 577 |
4.9% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Anima Sola | ??? | Defeat Delirium as Tainted Jacob | 600 |
3 | 4.1% | |
Esau Jr. | ??? | Defeat The Beast as Tainted Jacob | 507 |
2 | 3.9% | |
The Sun and the Moon | ??? | Defeat Ultra Greedier as Tainted Jacob | 542 |
4.4% | ||
Golden Trinket | ??? | Defeat Mega Satan as Tainted Jacob | 617 |
4.2% | ||
Soul of Jacob and Esau | ??? | Defeat Hush and Boss Rush as Tainted Jacob | 634 |
4.1% | ||
RC Remote | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Jacob | 580 |
3.9% | ||
Found Soul | ??? | Defeat Mother as Tainted Jacob | 581 |
3.9% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Lemegeton | ??? | Defeat Delirium as Tainted Bethany | 599 |
3 | 6.1% | |
Vengeful Spirit | ??? | Defeat The Beast as Tainted Bethany | 506 |
1 | 5.4% | |
Confessional | ??? | Defeat Mega Satan as Tainted Bethany | 616 |
6.5% | ||
Soul of Bethany | ??? | Defeat Hush and Boss Rush as Tainted Bethany | 633 |
6% | ||
Expansion Pack | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Bethany | 578 |
5.7% | ||
The Hierophant | ??? | Defeat Ultra Greedier as Tainted Bethany | 529 |
5.6% | ||
Beth's Essence | ??? | Defeat Mother as Tainted Bethany | 579 |
5.2% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Keeper's Kin | ??? | Defeat Delirium as Tainted Keeper | 596 |
2 | 6.2% | |
Strawman | ??? | Defeat The Beast as Tainted Keeper | 503 |
2 | 5.6% | |
The Hanged Man | ??? | Defeat Ultra Greedier as Tainted Keeper | 536 |
6.6% | ||
Golden Penny | ??? | Defeat Mega Satan as Tainted Keeper | 613 |
6.6% | ||
Soul of the Keeper | ??? | Defeat Hush and Boss Rush as Tainted Keeper | 630 |
6.3% | ||
Keeper's Bargain | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Keeper | 572 |
6.2% | ||
Cursed Penny | ??? | Defeat Mother as Tainted Keeper | 573 |
5.3% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Berserk! | ??? | Defeat Delirium as Tainted Samson | 590 |
2 | 5.8% | |
Larynx | ??? | Defeat The Beast as Tainted Samson | 497 |
2 | 5% | |
Crane Game | ??? | Defeat Mega Satan as Tainted Samson | 607 |
6.5% | ||
Soul of Samson | ??? | Defeat Hush and Boss Rush as Tainted Samson | 624 |
5.8% | ||
Strength | ??? | Defeat Ultra Greedier as Tainted Samson | 535 |
5.6% | ||
Temporary Tattoo | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Samson | 560 |
5.5% | ||
Swallowed M80 | ??? | Defeat Mother as Tainted Samson | 561 |
5% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Gello | ??? | Defeat Delirium as Tainted Lilith | 595 |
3 | 7% | |
Fool's Gold | ??? | Defeat Mega Satan as Tainted Lilith | 612 |
7.4% | ||
Soul of Lilith | ??? | Defeat Hush and Boss Rush as Tainted Lilith | 629 |
7.4% | ||
The High Priestess | ??? | Defeat Ultra Greedier as Tainted Lilith | 526 |
6.8% | ||
The Twins | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Lilith | 570 |
6.7% | ||
Adoption Papers | ??? | Defeat Mother as Tainted Lilith | 571 |
6.2% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Bag of Crafting | ??? | Defeat Delirium as Tainted Cain | 586 |
3 | 5.7% | |
Gold Pill | ??? | Defeat Mega Satan as Tainted Cain | 603 |
6% | ||
Wheel of Fortune | ??? | Defeat Ultra Greedier as Tainted Cain | 534 |
5.9% | ||
Gilded Key | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Cain | 552 |
5.4% | ||
Blue Key | ??? | Defeat The Beast as Tainted Cain | 493 |
5% | ||
Soul of Cain | ??? | Defeat Hush and Boss Rush as Tainted Cain | 620 |
5% | ||
Lucky Sack | ??? | Defeat Mother as Tainted Cain | 553 |
4.9% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Dark Arts | ??? | Defeat Delirium as Tainted Judas | 587 |
2 | 6.9% | |
Sanguine Bond | ??? | Defeat The Beast as Tainted Judas | 494 |
1 | 6.1% | |
Black Sack | ??? | Defeat Mega Satan as Tainted Judas | 604 |
7.4% | ||
Soul of Judas | ??? | Defeat Hush and Boss Rush as Tainted Judas | 621 |
6.9% | ||
The Magician | ??? | Defeat Ultra Greedier as Tainted Judas | 525 |
6.6% | ||
Your Soul | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Judas | 554 |
6.6% | ||
Number Magnet | ??? | Defeat Mother as Tainted Judas | 555 |
6% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Azazel's Rage | ??? | Defeat The Beast as Tainted Azazel | 498 |
2 | 6.1% | |
Hemoptysis | ??? | Defeat Delirium as Tainted Azazel | 591 |
1 | 6.8% | |
Hell Game | ??? | Defeat Mega Satan as Tainted Azazel | 608 |
7.2% | ||
Soul of Azazel | ??? | Defeat Hush and Boss Rush as Tainted Azazel | 625 |
7.1% | ||
The Devil | ??? | Defeat Ultra Greedier as Tainted Azazel | 539 |
6.5% | ||
Wicked Crown | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Azazel | 562 |
6.5% | ||
Azazel's Stump | ??? | Defeat Mother as Tainted Azazel | 563 |
5.8% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
Options? | Complete the final chapter with Isaac. | Defeat The Beast as Isaac | 441 |
2 | 14.8% | |
Isaac's Head | Unlocked a new item. | Complete the Boss Rush as Isaac | 70 |
36.8% | ||
Buddy Baby | Unlocked a new co-player baby. | Earn all Hard mode Completion Marks as Isaac | 253 |
17% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
The Swarm | ??? | Defeat The Beast as Tainted ??? | 495 |
2 | 4.1% | |
IBS | ??? | Defeat Delirium as Tainted ??? | 588 |
0 | 4.3% | |
The Emperor | ??? | Defeat Ultra Greedier as Tainted ??? | 528 |
4.6% | ||
Charming Poop | ??? | Defeat Mega Satan as Tainted ??? | 605 |
4.5% | ||
Soul of ??? | ??? | Defeat Hush and Boss Rush as Tainted ??? | 622 |
4.3% | ||
Dingle Berry | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted ??? | 556 |
4.2% | ||
Ring Cap | ??? | Defeat Mother as Tainted ??? | 557 |
4.1% |
Name | Description | Unlock | ID | Item Quality | % | Unlocked |
---|---|---|---|---|---|---|
TMTRAINER | ??? | Defeat The Beast as Tainted Eden | 500 |
0 | 4.3% | |
Wild Card | ??? | Defeat Mega Satan as Tainted Eden | 610 |
5% | ||
The World | ??? | Defeat Ultra Greedier as Tainted Eden | 544 |
4.8% | ||
Soul of Eden | ??? | Defeat Hush and Boss Rush as Tainted Eden | 627 |
4.8% | ||
Corrupted Data | ??? | Defeat Delirium as Tainted Eden | 593 |
4.6% | ||
Nuh Uh! | ??? | Defeat Isaac, ???, Satan, and The Lamb as Tainted Eden | 566 |
4.5% | ||
Modeling Clay | ??? | Defeat Mother as Tainted Eden | 567 |
4.2% |