This week I've been hacking around with some ideas about a runtime debugger for node (and probably browser JS too). These build upon some of the ideas loupe.
Run-time debugger is probably the wrong phrase, but I can't yet think of a better one - essentially what I mean is that all the code for building instrumenting/visualisating/debugging would be written in "userland" JS, rather than embedded in the JS engine itself.
This would obviously not be as powerful as a native engine debugger, with full access to the internals of v8 (or whichever engine), but I think the potential for hackability, and building things on top of it, is kinda interesting.