GitHub-flavored Markdown does not use C-style escapes for escaping backticks inside spans. Instead, GFM uses double, significant whitespaced, backticks.
Two backticks, then a space, then a backtick, then a space, then two more backticks:
`` ` ``
produces:
`
To my future @dwiyatci self: if you only wanna escape backtick in regular text (not code), simply use
\
(backslash) to escape it. Source here.`Good night, Glenn.`