There are a number of additional dependencies required for getting things installed on OS X. Starting with a blank slate OS X machine, this is the process it takes:
# Install Xcode Command Line Tools
# Install Homebrew
ruby -e "$(curl -fsSkL raw.github.com/mxcl/homebrew/go)"
# Some deps
brew install node spidermonkey closure-compiler yuicompressor
brew install llvm --with-clang
cd ~/Repos
git clone git://github.com/kripken/emscripten.git
@billmills I guess I'd better update the guide to use cURL, instead of wget. OS X comes pre-installed with the former instead of the latter.
Or, the alternative would be to ask people to install wget.